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Erschienen in: Cluster Computing 3/2015

01.09.2015

A network approach for managing and processing big cancer data in clouds

verfasst von: Wei Xing, Wei Jie, Dimitrios Tsoumakos, Moustafa Ghanem

Erschienen in: Cluster Computing | Ausgabe 3/2015

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Abstract

Translational cancer research requires integrative analysis of multiple levels of big cancer data to identify and treat cancer. In order to address the issues that data is decentralised, growing and continually being updated, and the content living or archiving on different information sources partially overlaps creating redundancies as well as contradictions and inconsistencies, we develop a data network model and technology for constructing and managing big cancer data. To support our data network approach for data process and analysis, we employ a semantic content network approach and adopt the CELAR cloud platform. The prototype implementation shows that the CELAR cloud can satisfy the on-demanding needs of various data resources for management and process of big cancer data.

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Literatur
1.
Zurück zum Zitat Lawrence, M., Stojanov, P., Mermel, C., Robinson, J., Garraway, L., Golub, T., Meyerson, M., Gabriel, S., Lander, E., Getz, G.: Discovery and saturation analysis of cancer genes across 21 tumour types. Nature 505(5), 495–501 (2014)CrossRef Lawrence, M., Stojanov, P., Mermel, C., Robinson, J., Garraway, L., Golub, T., Meyerson, M., Gabriel, S., Lander, E., Getz, G.: Discovery and saturation analysis of cancer genes across 21 tumour types. Nature 505(5), 495–501 (2014)CrossRef
2.
Zurück zum Zitat Chen, R., Mias, G., Li-Pook-Than, J., Jiang, L., Lam, H., Chen, R., Miriami, E., Karczewski, K., Hariharan, M., Dewey, F., Cheng, Y., Clark, M., Im, H., Habegger, L., Balasubramanian, S., O’Huallachain, M., Dudley, J., Hillenmeyer, S., Haraksingh, R., Sharon, D., Euskirchen, G., Lacroute, P., Bettinger, K., Boyle, A., Kasowski, M., Grubert, F., Seki, S., Garcia, M., Whirl-Carrillo, M., Gallardo, M., Blasco, M., Greenberg, P., Snyder, P., Klein, T., Altman, R., Butte, A.J., Ashley, E., Gerstein, M., Nadeau, K., Tang, H., Snyder, M.: Personal omics profiling reveals dynamic molecular and medical phenotypes. Cell 148(6), 1293–1307 (2012)CrossRef Chen, R., Mias, G., Li-Pook-Than, J., Jiang, L., Lam, H., Chen, R., Miriami, E., Karczewski, K., Hariharan, M., Dewey, F., Cheng, Y., Clark, M., Im, H., Habegger, L., Balasubramanian, S., O’Huallachain, M., Dudley, J., Hillenmeyer, S., Haraksingh, R., Sharon, D., Euskirchen, G., Lacroute, P., Bettinger, K., Boyle, A., Kasowski, M., Grubert, F., Seki, S., Garcia, M., Whirl-Carrillo, M., Gallardo, M., Blasco, M., Greenberg, P., Snyder, P., Klein, T., Altman, R., Butte, A.J., Ashley, E., Gerstein, M., Nadeau, K., Tang, H., Snyder, M.: Personal omics profiling reveals dynamic molecular and medical phenotypes. Cell 148(6), 1293–1307 (2012)CrossRef
3.
Zurück zum Zitat Hanahan, D., Weinberg, R.: Hallmarks of cancer: the next generation. Cell 144(5), 646–674 (2011)CrossRef Hanahan, D., Weinberg, R.: Hallmarks of cancer: the next generation. Cell 144(5), 646–674 (2011)CrossRef
4.
Zurück zum Zitat Weinberg, R.A.: Coming full circlefrom endless complexity to simplicity and back again. Cell 157(1), 267–271 (2014)MathSciNetCrossRef Weinberg, R.A.: Coming full circlefrom endless complexity to simplicity and back again. Cell 157(1), 267–271 (2014)MathSciNetCrossRef
5.
Zurück zum Zitat Giannakopoulos, I., Papailiou, N., Mantas, C., Konstantinou, I., Tsoumakos, D., Koziris, N.: CELAR: Automated Application Elasticity Platform. IEEE International Conference on Big Data (2014) Giannakopoulos, I., Papailiou, N., Mantas, C., Konstantinou, I., Tsoumakos, D., Koziris, N.: CELAR: Automated Application Elasticity Platform. IEEE International Conference on Big Data (2014)
6.
Zurück zum Zitat Copil, G., Moldovan, D., Le, D.-H., Truong, H.-L., Dustdar, S., Sofokleous, C., Loulloudes, N., Trihinas, D., Pallis, G., Dikaiakos, M.D., Sheridan, C., Floros, E., Loverdos, C.K., Star, K., Xing, W.: On controlling elasticity of cloud applications in celar. In: Emerging Research in Cloud Distributed Computing Systems. Software Engineering, and High Performance Computing Book Series, Advances in Systems Analysis (2015) Copil, G., Moldovan, D., Le, D.-H., Truong, H.-L., Dustdar, S., Sofokleous, C., Loulloudes, N., Trihinas, D., Pallis, G., Dikaiakos, M.D., Sheridan, C., Floros, E., Loverdos, C.K., Star, K., Xing, W.: On controlling elasticity of cloud applications in celar. In: Emerging Research in Cloud Distributed Computing Systems. Software Engineering, and High Performance Computing Book Series, Advances in Systems Analysis (2015)
7.
Zurück zum Zitat Xing, W., Corcho, O., Goble, C., Dikaiakos, M.D.: An ActOn-based semantic information service for Grids. J. Future Gener. Comput. Syst. 26(3), March (2010) Xing, W., Corcho, O., Goble, C., Dikaiakos, M.D.: An ActOn-based semantic information service for Grids. J. Future Gener. Comput. Syst. 26(3), March (2010)
8.
Zurück zum Zitat Xing, W., Corcho, O., Goble, C., Dikaiakos, M.: Active ontology: an information integration approach for highly dynamic information sources. In: European Semantic Web Conference. Innsbruck, Austria (2007) Xing, W., Corcho, O., Goble, C., Dikaiakos, M.: Active ontology: an information integration approach for highly dynamic information sources. In: European Semantic Web Conference. Innsbruck, Austria (2007)
9.
Zurück zum Zitat Wang, L., Khan, S.U., Chen, D., Kolodziej, J., Ranjan, R., Xu, C., Zomaya, A.Y.: Energy-aware parallel task scheduling in a cluster. Future Gener. Comput. Syst. 29(7), 1661–1670 (2013)CrossRef Wang, L., Khan, S.U., Chen, D., Kolodziej, J., Ranjan, R., Xu, C., Zomaya, A.Y.: Energy-aware parallel task scheduling in a cluster. Future Gener. Comput. Syst. 29(7), 1661–1670 (2013)CrossRef
10.
Zurück zum Zitat Wang, L., Kunze, M., Tao, J., von Laszewski, G.: Towards building a cloud for scientific applications. Adv. Eng. Softw. 42(9), September (2011) Wang, L., Kunze, M., Tao, J., von Laszewski, G.: Towards building a cloud for scientific applications. Adv. Eng. Softw. 42(9), September (2011)
11.
Zurück zum Zitat Wang, L., Chen, D., Hu, Y., Ma, Y., Wang, J.: Towards enabling cyberinfrastructure as a service in clouds. Comput. Electr. Eng. 39(1), 3–14 (2013)CrossRef Wang, L., Chen, D., Hu, Y., Ma, Y., Wang, J.: Towards enabling cyberinfrastructure as a service in clouds. Comput. Electr. Eng. 39(1), 3–14 (2013)CrossRef
12.
Zurück zum Zitat Xing, W., Liabotis, I., Tsoumakos, D., Sofokleous, S., Floros, V., Loverdos, C.: Translational cancer detection pipeline design (v1.0). Tech. Rep, EU CELAR Project (March 2013) Xing, W., Liabotis, I., Tsoumakos, D., Sofokleous, S., Floros, V., Loverdos, C.: Translational cancer detection pipeline design (v1.0). Tech. Rep, EU CELAR Project (March 2013)
14.
Zurück zum Zitat Rebholz-Schuhmann, D., Kirsch, H., Gaudan, S., Arregui, M., Nenadic, G.: Annotation and disambiguation of semantic types in biomedical text: a cascaded approach to named entity recognition. In: Proceedings of the EACL Workshop on Multi-Dimensional Markup in NLP, Trente, Italy (2006) Rebholz-Schuhmann, D., Kirsch, H., Gaudan, S., Arregui, M., Nenadic, G.: Annotation and disambiguation of semantic types in biomedical text: a cascaded approach to named entity recognition. In: Proceedings of the EACL Workshop on Multi-Dimensional Markup in NLP, Trente, Italy (2006)
15.
Zurück zum Zitat del Castillo, J.C.: Bioalma’s text mining solutions for biomedical research. ALMA Bioinformatics, S.L. (2002) del Castillo, J.C.: Bioalma’s text mining solutions for biomedical research. ALMA Bioinformatics, S.L. (2002)
16.
Zurück zum Zitat Fernandez, J., Hoffmann, R., Valencia, A.: iHOP web services family. In: Freitas, A., Navarro, A. (eds.) Bioinformatics for Personalized Medicine, ser. Lecture Notes in Computer Science, vol. 6620, pp. 102–107 (2012) Fernandez, J., Hoffmann, R., Valencia, A.: iHOP web services family. In: Freitas, A., Navarro, A. (eds.) Bioinformatics for Personalized Medicine, ser. Lecture Notes in Computer Science, vol. 6620, pp. 102–107 (2012)
18.
Zurück zum Zitat Zdobnov, E.M., Lopez, R., Apweiler, R., Etzold, T.: The EBI SRS server recent developments. Bioinformatics 18(2), 368–373 (2002)CrossRef Zdobnov, E.M., Lopez, R., Apweiler, R., Etzold, T.: The EBI SRS server recent developments. Bioinformatics 18(2), 368–373 (2002)CrossRef
19.
Zurück zum Zitat Hekkelman, H.L., Vriend, G.: MRS: a fast and compact retrieval system for biological data. Nucl. Acids Res. 33(Web-Server-Issue), 766–769, 2005 Hekkelman, H.L., Vriend, G.: MRS: a fast and compact retrieval system for biological data. Nucl. Acids Res. 33(Web-Server-Issue), 766–769, 2005
20.
Zurück zum Zitat Xiong, P., Chi, Y., Zhu, S., Moon, H.J., Pu, C., Hacigumus, H.: Intelligent management of virtualized resources for database systems in cloud environment. In: IEEE 27th International Conference on Data Engineering, pp. 87–98, April (2011) Xiong, P., Chi, Y., Zhu, S., Moon, H.J., Pu, C., Hacigumus, H.: Intelligent management of virtualized resources for database systems in cloud environment. In: IEEE 27th International Conference on Data Engineering, pp. 87–98, April (2011)
21.
Zurück zum Zitat Wang, L., von Laszewski, G., Dayal, J., He, X., Younge, A.J., Furlani, T.R.: Towards thermal aware workload scheduling in a data center. In: Proceedings of the 10th International Symposium on Pervasive Systems, Algorithms, and Networks, pp. 116–122, December (2009) Wang, L., von Laszewski, G., Dayal, J., He, X., Younge, A.J., Furlani, T.R.: Towards thermal aware workload scheduling in a data center. In: Proceedings of the 10th International Symposium on Pervasive Systems, Algorithms, and Networks, pp. 116–122, December (2009)
22.
Zurück zum Zitat Wang, L., von Laszewski, G., Younge, A.J., He, X., Kunze, M., Tao, J., Fu, C.: Cloud computing: a perspective study. New Gener. Comput. 28(2), 137–146 (2010)CrossRefMATH Wang, L., von Laszewski, G., Younge, A.J., He, X., Kunze, M., Tao, J., Fu, C.: Cloud computing: a perspective study. New Gener. Comput. 28(2), 137–146 (2010)CrossRefMATH
23.
Zurück zum Zitat Rao, J., Bu, X., Xu, C.-Z., Wang, K.: A distributed self-learning approach for elastic provisioning of virtualized cloud resources. In: 2011 IEEE 19th International Symposium on Modeling, Analysis Simulation of Computer and Telecommunication Systems, pp. 45–54, July (2011) Rao, J., Bu, X., Xu, C.-Z., Wang, K.: A distributed self-learning approach for elastic provisioning of virtualized cloud resources. In: 2011 IEEE 19th International Symposium on Modeling, Analysis Simulation of Computer and Telecommunication Systems, pp. 45–54, July (2011)
24.
Zurück zum Zitat Sharma, U., Shenoy, P., Sahu, S., Shaikh, A.: A cost-aware elasticity provisioning system for the cloud. In: 31st International Conference on Distributed Computing Systems, pp. 559–570, June (2011) Sharma, U., Shenoy, P., Sahu, S., Shaikh, A.: A cost-aware elasticity provisioning system for the cloud. In: 31st International Conference on Distributed Computing Systems, pp. 559–570, June (2011)
25.
Zurück zum Zitat Giannakopoulos, I., Papailiou, N., Mantas, C., Konstantinou, I., Tsoumakos, D., Koziris, N.: CELAR: automated application elasticity platform. In: 2014 IEEE International Conference on Big Data, Big Data 2014, pp. 23–25 (2014) Giannakopoulos, I., Papailiou, N., Mantas, C., Konstantinou, I., Tsoumakos, D., Koziris, N.: CELAR: automated application elasticity platform. In: 2014 IEEE International Conference on Big Data, Big Data 2014, pp. 23–25 (2014)
Metadaten
Titel
A network approach for managing and processing big cancer data in clouds
verfasst von
Wei Xing
Wei Jie
Dimitrios Tsoumakos
Moustafa Ghanem
Publikationsdatum
01.09.2015
Verlag
Springer US
Erschienen in
Cluster Computing / Ausgabe 3/2015
Print ISSN: 1386-7857
Elektronische ISSN: 1573-7543
DOI
https://doi.org/10.1007/s10586-015-0456-6

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