2014 | OriginalPaper | Buchkapitel
A Simulation for Proportional Biological Operational Mu-Circuit
verfasst von : Dechang Xu, Zhipeng Cai, Ke Liu, Xiangmiao Zeng, Yujing Ouyang, Cuihong Dai, Aiju Hou, Dayou Cheng, Jianzhong Li
Erschienen in: Bioinformatics Research and Applications
Verlag: Springer International Publishing
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To quantitatively control the expression of target gene is challenging but highly desired in practice. We design a device-Biological Proportional Operational Mu-circuit (P-BOM) incorporating AND/OR gate and operational amplifier into one circuit and explore its behaviors through simulation. The results imply that we can control input-output proportionly by manipulating the RBS of
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R and output gene.