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2019 | OriginalPaper | Buchkapitel

Auto-classification of Retinal Diseases in the Limit of Sparse Data Using a Two-Streams Machine Learning Model

verfasst von : C.-H. Huck Yang, Fangyu Liu, Jia-Hong Huang, Meng Tian, M. D. I-Hung Lin, Yi Chieh Liu, Hiromasa Morikawa, Hao-Hsiang Yang, Jesper Tegnèr

Erschienen in: Computer Vision – ACCV 2018 Workshops

Verlag: Springer International Publishing

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Abstract

Automatic clinical diagnosis of retinal diseases has emerged as a promising approach to facilitate discovery in areas with limited access to specialists. Based on the fact that fundus structure and vascular disorders are the main characteristics of retinal diseases, we propose a novel visual-assisted diagnosis hybrid model mixing the support vector machine (SVM) and deep neural networks (DNNs). Furthermore, we present a new clinical retina labels collection sorted by the professional ophthalmologist from the educational project Retina Image Bank, called EyeNet, for ophthalmology incorporating 52 retina diseases classes. Using EyeNet, our model achieves 90.40% diagnosis accuracy, and the model performance is comparable to the professional ophthalmologists (https://​github.​com/​huckiyang/​EyeNet2).

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Literatur
1.
Zurück zum Zitat Tan, O., et al.: Detection of macular ganglion cell loss in glaucoma by Fourier-domain optical coherence tomography. Ophthalmology 116, 2305–2314 (2009)CrossRef Tan, O., et al.: Detection of macular ganglion cell loss in glaucoma by Fourier-domain optical coherence tomography. Ophthalmology 116, 2305–2314 (2009)CrossRef
2.
Zurück zum Zitat Lalezary, M., et al.: Baseline optical coherence tomography predicts the development of glaucomatous change in glaucoma suspects. Am. J. Ophthalmol. 142, 576–582 (2006)CrossRef Lalezary, M., et al.: Baseline optical coherence tomography predicts the development of glaucomatous change in glaucoma suspects. Am. J. Ophthalmol. 142, 576–582 (2006)CrossRef
3.
Zurück zum Zitat Sharifi, M., Fathy, M., Mahmoudi, M.T.: A classified and comparative study of edge detection algorithms. In: International Conference on Information Technology: Coding and Computing, Proceedings, pp. 117–120. IEEE (2002) Sharifi, M., Fathy, M., Mahmoudi, M.T.: A classified and comparative study of edge detection algorithms. In: International Conference on Information Technology: Coding and Computing, Proceedings, pp. 117–120. IEEE (2002)
4.
Zurück zum Zitat Abràmoff, M.D., Garvin, M.K., Sonka, M.: Retinal imaging and image analysis. Rev. Biomed. Eng. 3, 169–208 (2010)CrossRef Abràmoff, M.D., Garvin, M.K., Sonka, M.: Retinal imaging and image analysis. Rev. Biomed. Eng. 3, 169–208 (2010)CrossRef
5.
Zurück zum Zitat Pizzarello, L., et al.: Vision 2020: the right to sight: a global initiative to eliminate avoidable blindness. Arch. Ophthalmol. 122, 615–620 (2004)CrossRef Pizzarello, L., et al.: Vision 2020: the right to sight: a global initiative to eliminate avoidable blindness. Arch. Ophthalmol. 122, 615–620 (2004)CrossRef
6.
Zurück zum Zitat Bhattacharya, S.: Watermarking digital images using fuzzy matrix compositions and (\(\alpha \), \(\beta \))-cut of fuzzy set. Int. J. Adv. Comput. 5, 135 (2014) Bhattacharya, S.: Watermarking digital images using fuzzy matrix compositions and (\(\alpha \), \(\beta \))-cut of fuzzy set. Int. J. Adv. Comput. 5, 135 (2014)
7.
Zurück zum Zitat Lin, C.Y., Wu, M., Bloom, J.A., Cox, I.J., Miller, M.L., Lui, Y.M.: Rotation-, scale-, and translation-resilient public watermarking for images. In: Security and Watermarking of Multimedia Contents II, vol. 3971, pp. 90–99. International Society for Optics and Photonics (2000) Lin, C.Y., Wu, M., Bloom, J.A., Cox, I.J., Miller, M.L., Lui, Y.M.: Rotation-, scale-, and translation-resilient public watermarking for images. In: Security and Watermarking of Multimedia Contents II, vol. 3971, pp. 90–99. International Society for Optics and Photonics (2000)
8.
Zurück zum Zitat Cochocki, A., Unbehauen, R.: Neural Networks for Optimization and Signal Processing. Wiley, New York (1993) Cochocki, A., Unbehauen, R.: Neural Networks for Optimization and Signal Processing. Wiley, New York (1993)
10.
Zurück zum Zitat Deng, J., Dong, W., Socher, R., Li, L.J., Li, K., Fei-Fei, L.: ImageNet: a large-scale hierarchical image database. In: IEEE Conference on Computer Vision and Pattern Recognition, CVPR 2009, pp. 248–255. IEEE (2009) Deng, J., Dong, W., Socher, R., Li, L.J., Li, K., Fei-Fei, L.: ImageNet: a large-scale hierarchical image database. In: IEEE Conference on Computer Vision and Pattern Recognition, CVPR 2009, pp. 248–255. IEEE (2009)
11.
Zurück zum Zitat Rajpurkar, P., Zhang, J., Lopyrev, K., Liang, P.: Squad: 100,000+ questions for machine comprehension of text. arXiv preprint arXiv:1606.05250 (2016) Rajpurkar, P., Zhang, J., Lopyrev, K., Liang, P.: Squad: 100,000+ questions for machine comprehension of text. arXiv preprint arXiv:​1606.​05250 (2016)
12.
Zurück zum Zitat Antol, S., et al.: VQA: Visual question answering. In: Proceedings of the ICCV, pp. 2425–2433 (2015) Antol, S., et al.: VQA: Visual question answering. In: Proceedings of the ICCV, pp. 2425–2433 (2015)
14.
Zurück zum Zitat Huang, J.H., Dao, C.D., Alfadly, M., Ghanem, B.: A novel framework for robustness analysis of visual qa models. arXiv:1711.06232 (2017) Huang, J.H., Dao, C.D., Alfadly, M., Ghanem, B.: A novel framework for robustness analysis of visual qa models. arXiv:​1711.​06232 (2017)
15.
16.
Zurück zum Zitat Esteva, A., et al.: Dermatologist-level classification of skin cancer with deep neural networks. Nature 542, 115 (2017)CrossRef Esteva, A., et al.: Dermatologist-level classification of skin cancer with deep neural networks. Nature 542, 115 (2017)CrossRef
17.
Zurück zum Zitat Gulshan, V., et al.: Development and validation of a deep learning algorithm for detection of diabetic retinopathy in retinal fundus photographs. JAMA 316, 2402–2410 (2016)CrossRef Gulshan, V., et al.: Development and validation of a deep learning algorithm for detection of diabetic retinopathy in retinal fundus photographs. JAMA 316, 2402–2410 (2016)CrossRef
18.
Zurück zum Zitat Rajpurkar, P., Hannun, A.Y., Haghpanahi, M., Bourn, C., Ng, A.Y.: Cardiologist-level arrhythmia detection with convolutional neural networks. arXiv preprint arXiv:1707.01836 (2017) Rajpurkar, P., Hannun, A.Y., Haghpanahi, M., Bourn, C., Ng, A.Y.: Cardiologist-level arrhythmia detection with convolutional neural networks. arXiv preprint arXiv:​1707.​01836 (2017)
19.
Zurück zum Zitat Rajpurkar, P., et al.: CheXNet: Radiologist-level pneumonia detection on chest X-rays with deep learning. arXiv preprint arXiv:1711.05225 (2017) Rajpurkar, P., et al.: CheXNet: Radiologist-level pneumonia detection on chest X-rays with deep learning. arXiv preprint arXiv:​1711.​05225 (2017)
20.
Zurück zum Zitat Grewal, M., Srivastava, M.M., Kumar, P., Varadarajan, S.: RADNET: radiologist level accuracy using deep learning for hemorrhage detection in ct scans. In: 2018 IEEE 15th International Symposium on Biomedical Imaging (ISBI 2018), pp. 281–284. IEEE (2018) Grewal, M., Srivastava, M.M., Kumar, P., Varadarajan, S.: RADNET: radiologist level accuracy using deep learning for hemorrhage detection in ct scans. In: 2018 IEEE 15th International Symposium on Biomedical Imaging (ISBI 2018), pp. 281–284. IEEE (2018)
21.
Zurück zum Zitat Bejnordi, B.E., et al.: Diagnostic assessment of deep learning algorithms for detection of lymph node metastases in women with breast cancer. JAMA 318, 2199–2210 (2017)CrossRef Bejnordi, B.E., et al.: Diagnostic assessment of deep learning algorithms for detection of lymph node metastases in women with breast cancer. JAMA 318, 2199–2210 (2017)CrossRef
22.
Zurück zum Zitat Gale, W., Oakden-Rayner, L., Carneiro, G., Bradley, A.P., Palmer, L.J.: Detecting hip fractures with radiologist-level performance using deep neural networks. arXiv preprint arXiv:1711.06504 (2017) Gale, W., Oakden-Rayner, L., Carneiro, G., Bradley, A.P., Palmer, L.J.: Detecting hip fractures with radiologist-level performance using deep neural networks. arXiv preprint arXiv:​1711.​06504 (2017)
23.
Zurück zum Zitat Wang, X., Peng, Y., Lu, L., Lu, Z., Bagheri, M., Summers, R.M.: ChestX-ray8: hospital-scale chest x-ray database and benchmarks on weakly-supervised classification and localization of common thorax diseases. In: 2017 IEEE Conference on Computer Vision and Pattern Recognition (CVPR), pp. 3462–3471. IEEE (2017) Wang, X., Peng, Y., Lu, L., Lu, Z., Bagheri, M., Summers, R.M.: ChestX-ray8: hospital-scale chest x-ray database and benchmarks on weakly-supervised classification and localization of common thorax diseases. In: 2017 IEEE Conference on Computer Vision and Pattern Recognition (CVPR), pp. 3462–3471. IEEE (2017)
24.
Zurück zum Zitat Staal, J., Abràmoff, M.D., Niemeijer, M., Viergever, M.A., Van Ginneken, B.: Ridge-based vessel segmentation in color images of the retina. TMI 23, 501–509 (2004) Staal, J., Abràmoff, M.D., Niemeijer, M., Viergever, M.A., Van Ginneken, B.: Ridge-based vessel segmentation in color images of the retina. TMI 23, 501–509 (2004)
25.
Zurück zum Zitat Gertych, A., Zhang, A., Sayre, J., Pospiech-Kurkowska, S., Huang, H.: Bone age assessment of children using a digital hand atlas. Comput. Med. Imaging Graph. 31, 322–331 (2007)CrossRef Gertych, A., Zhang, A., Sayre, J., Pospiech-Kurkowska, S., Huang, H.: Bone age assessment of children using a digital hand atlas. Comput. Med. Imaging Graph. 31, 322–331 (2007)CrossRef
26.
Zurück zum Zitat Rajpurkar, P., et al.: Mura dataset: towards radiologist-level abnormality detection in musculoskeletal radiographs. arXiv preprint arXiv:1712.06957 (2017) Rajpurkar, P., et al.: Mura dataset: towards radiologist-level abnormality detection in musculoskeletal radiographs. arXiv preprint arXiv:​1712.​06957 (2017)
27.
Zurück zum Zitat Heath, M., Bowyer, K., Kopans, D., Moore, R., Kegelmeyer, P.: The digital database for screening mammography. In: Digital Mammography, pp. 431–434 (2000) Heath, M., Bowyer, K., Kopans, D., Moore, R., Kegelmeyer, P.: The digital database for screening mammography. In: Digital Mammography, pp. 431–434 (2000)
28.
Zurück zum Zitat Costa, J.A., Hero, A.: Classification constrained dimensionality reduction. In: IEEE International Conference on Acoustics, Speech, and Signal Processing, 2005. Proceedings, (ICASSP’05), vol. 5, pp. 1077. IEEE (2005) Costa, J.A., Hero, A.: Classification constrained dimensionality reduction. In: IEEE International Conference on Acoustics, Speech, and Signal Processing, 2005. Proceedings, (ICASSP’05), vol. 5, pp. 1077. IEEE (2005)
29.
Zurück zum Zitat Fukunaga, K.: Introduction to Statistical Pattern Recognition. Academic Press, London (2013)MATH Fukunaga, K.: Introduction to Statistical Pattern Recognition. Academic Press, London (2013)MATH
30.
Zurück zum Zitat Jimenez, L.O., Landgrebe, D.A.: Supervised classification in high-dimensional space: geometrical, statistical, and asymptotical properties of multivariate data. IEEE Trans. Syst. Man Cybern. Part C (Appl. Rev.) 28, 39–54 (1998)CrossRef Jimenez, L.O., Landgrebe, D.A.: Supervised classification in high-dimensional space: geometrical, statistical, and asymptotical properties of multivariate data. IEEE Trans. Syst. Man Cybern. Part C (Appl. Rev.) 28, 39–54 (1998)CrossRef
31.
Zurück zum Zitat Yang, Z., He, X., Gao, J., Deng, L., Smola, A.: Stacked attention networks for image question answering. In: Proceedings of the IEEE Conference on Computer Vision and Pattern Recognition, pp. 21–29 (2016) Yang, Z., He, X., Gao, J., Deng, L., Smola, A.: Stacked attention networks for image question answering. In: Proceedings of the IEEE Conference on Computer Vision and Pattern Recognition, pp. 21–29 (2016)
32.
Zurück zum Zitat Trier, Ø.D., Jain, A.K., Taxt, T.: Feature extraction methods for character recognition-a survey. Pattern Recogn. 29, 641–662 (1996)CrossRef Trier, Ø.D., Jain, A.K., Taxt, T.: Feature extraction methods for character recognition-a survey. Pattern Recogn. 29, 641–662 (1996)CrossRef
33.
Zurück zum Zitat Srihari, R., Li, W.: Information extraction supported question answering. Technical report, Cymfony Net Inc., Williamsville NY (1999) Srihari, R., Li, W.: Information extraction supported question answering. Technical report, Cymfony Net Inc., Williamsville NY (1999)
34.
Zurück zum Zitat Somers, H.: Example-based machine translation. Mach. Transl. 14, 113–157 (1999)CrossRef Somers, H.: Example-based machine translation. Mach. Transl. 14, 113–157 (1999)CrossRef
35.
Zurück zum Zitat Bahdanau, D., Cho, K., Bengio, Y.: Neural machine translation by jointly learning to align and translate. arXiv preprint arXiv:1409.0473 (2014) Bahdanau, D., Cho, K., Bengio, Y.: Neural machine translation by jointly learning to align and translate. arXiv preprint arXiv:​1409.​0473 (2014)
36.
Zurück zum Zitat Ciresan, D., Giusti, A., Gambardella, L.M., Schmidhuber, J.: Deep neural networks segment neuronal membranes in electron microscopy images. In: Advances in neural information processing systems, pp. 2843–2851 (2012) Ciresan, D., Giusti, A., Gambardella, L.M., Schmidhuber, J.: Deep neural networks segment neuronal membranes in electron microscopy images. In: Advances in neural information processing systems, pp. 2843–2851 (2012)
37.
Zurück zum Zitat Hariharan, B., Arbeláez, P., Girshick, R., Malik, J.: Hypercolumns for object segmentation and fine-grained localization. In: Proceedings of the IEEE conference on computer vision and pattern recognition, pp. 447–456 (2015) Hariharan, B., Arbeláez, P., Girshick, R., Malik, J.: Hypercolumns for object segmentation and fine-grained localization. In: Proceedings of the IEEE conference on computer vision and pattern recognition, pp. 447–456 (2015)
38.
Zurück zum Zitat Seyedhosseini, M., Sajjadi, M., Tasdizen, T.: Image segmentation with cascaded hierarchical models and logistic disjunctive normal networks. In: 2013 IEEE International Conference on Computer Vision (ICCV), pp. 2168–2175. IEEE(2013) Seyedhosseini, M., Sajjadi, M., Tasdizen, T.: Image segmentation with cascaded hierarchical models and logistic disjunctive normal networks. In: 2013 IEEE International Conference on Computer Vision (ICCV), pp. 2168–2175. IEEE(2013)
40.
Zurück zum Zitat Long, J., Shelhamer, E., Darrell, T.: Fully convolutional networks for semantic segmentation. In: Proceedings of the IEEE conference on computer vision and pattern recognition, pp. 3431–3440 (2015) Long, J., Shelhamer, E., Darrell, T.: Fully convolutional networks for semantic segmentation. In: Proceedings of the IEEE conference on computer vision and pattern recognition, pp. 3431–3440 (2015)
41.
42.
Zurück zum Zitat Khurana, A.: Comprehensive Ophthalmology. New Age International Ltd. (2007) Khurana, A.: Comprehensive Ophthalmology. New Age International Ltd. (2007)
43.
Zurück zum Zitat Rezaee, K., Haddadnia, J., Tashk, A.: Optimized clinical segmentation of retinal blood vessels by using combination of adaptive filtering, fuzzy entropy and skeletonization. Appl. Soft Comput. 52, 937–951 (2017)CrossRef Rezaee, K., Haddadnia, J., Tashk, A.: Optimized clinical segmentation of retinal blood vessels by using combination of adaptive filtering, fuzzy entropy and skeletonization. Appl. Soft Comput. 52, 937–951 (2017)CrossRef
44.
Zurück zum Zitat Turk, M.A., Pentland, A.P.: Face recognition using eigenfaces. In: IEEE Computer Society Conference on Computer Vision and Pattern Recognition, Proceedings CVPR 1991, pp. 586–591. IEEE (1991) Turk, M.A., Pentland, A.P.: Face recognition using eigenfaces. In: IEEE Computer Society Conference on Computer Vision and Pattern Recognition, Proceedings CVPR 1991, pp. 586–591. IEEE (1991)
45.
Zurück zum Zitat Lyons, M.J., Budynek, J., Akamatsu, S.: Automatic classification of single facial images. IEEE Trans. Pattern Anal. Mach. Intell. 21, 1357–1362 (1999)CrossRef Lyons, M.J., Budynek, J., Akamatsu, S.: Automatic classification of single facial images. IEEE Trans. Pattern Anal. Mach. Intell. 21, 1357–1362 (1999)CrossRef
46.
Zurück zum Zitat Wu, J., Zhou, Z.H.: Face recognition with one training image per person. Pattern Recogn. Lett. 23, 1711–1719 (2002)CrossRef Wu, J., Zhou, Z.H.: Face recognition with one training image per person. Pattern Recogn. Lett. 23, 1711–1719 (2002)CrossRef
47.
Zurück zum Zitat Moghaddam, B., Wahid, W., Pentland, A.: Beyond eigenfaces: probabilistic matching for face recognition. In: Third IEEE International Conference on Automatic Face and Gesture Recognition, 1998. Proceedings, pp. 30–35. IEEE (1998) Moghaddam, B., Wahid, W., Pentland, A.: Beyond eigenfaces: probabilistic matching for face recognition. In: Third IEEE International Conference on Automatic Face and Gesture Recognition, 1998. Proceedings, pp. 30–35. IEEE (1998)
48.
Zurück zum Zitat Akram, M.U., Tariq, A., Khan, S.A.: Retinal recognition: Personal identification using blood vessels. In: 2011 International Conference for Internet Technology and Secured Transactions (ICITST), pp. 180–184. IEEE (2011) Akram, M.U., Tariq, A., Khan, S.A.: Retinal recognition: Personal identification using blood vessels. In: 2011 International Conference for Internet Technology and Secured Transactions (ICITST), pp. 180–184. IEEE (2011)
49.
Zurück zum Zitat Kuo, B.C., Ho, H.H., Li, C.H., Hung, C.C., Taur, J.S.: A kernel-based feature selection method for SVM with RBF kernel for hyperspectral image classification. IEEE J.Sel. Top. Appl. Earth Observ. Remote Sens. 7, 317–326 (2014)CrossRef Kuo, B.C., Ho, H.H., Li, C.H., Hung, C.C., Taur, J.S.: A kernel-based feature selection method for SVM with RBF kernel for hyperspectral image classification. IEEE J.Sel. Top. Appl. Earth Observ. Remote Sens. 7, 317–326 (2014)CrossRef
50.
Zurück zum Zitat Crick, R.P., Khaw, P.T.: A Textbook of Clinical Ophthalmology: A Practical Guide to Disorders of the Eyes and Their Management. World Scientific Crick, R.P., Khaw, P.T.: A Textbook of Clinical Ophthalmology: A Practical Guide to Disorders of the Eyes and Their Management. World Scientific
51.
Zurück zum Zitat Akram, I., Rubinstein, A.: Common retinal signs. an overview. Optometry Today (2005) Akram, I., Rubinstein, A.: Common retinal signs. an overview. Optometry Today (2005)
52.
Zurück zum Zitat Tang, S., Huang, L., Wang, Y., Wang, Y.: Contrast-enhanced ultrasonography diagnosis of fundal localized type of gallbladder adenomyomatosis. BMC Gastroenterol. 15, 99 (2015)CrossRef Tang, S., Huang, L., Wang, Y., Wang, Y.: Contrast-enhanced ultrasonography diagnosis of fundal localized type of gallbladder adenomyomatosis. BMC Gastroenterol. 15, 99 (2015)CrossRef
53.
Zurück zum Zitat Noyel, G., Thomas, R., Bhakta, G., Crowder, A., Owens, D., Boyle, P.: Superimposition of eye fundus images for longitudinal analysis from large public health databases. Biomed. Phys. Eng. Express 3, 045015 (2017)CrossRef Noyel, G., Thomas, R., Bhakta, G., Crowder, A., Owens, D., Boyle, P.: Superimposition of eye fundus images for longitudinal analysis from large public health databases. Biomed. Phys. Eng. Express 3, 045015 (2017)CrossRef
55.
Zurück zum Zitat Krizhevsky, A., Sutskever, I., Hinton, G.E.: ImageNet classification with deep convolutional neural networks. In: Advances in NIPS, pp. 1097–1105 (2012) Krizhevsky, A., Sutskever, I., Hinton, G.E.: ImageNet classification with deep convolutional neural networks. In: Advances in NIPS, pp. 1097–1105 (2012)
56.
Zurück zum Zitat Xie, S., Girshick, R., Dollár, P., Tu, Z., He, K.: Aggregated residual transformations for deep neural networks. In: CVPR, pp. 5987–5995. IEEE (2017) Xie, S., Girshick, R., Dollár, P., Tu, Z., He, K.: Aggregated residual transformations for deep neural networks. In: CVPR, pp. 5987–5995. IEEE (2017)
57.
Zurück zum Zitat Nair, V., Hinton, G.E.: Rectified linear units improve restricted boltzmann machines. In: Proceedings of the 27th International Conference on Machine Learning (ICML-2010), pp. 807–814 (2010) Nair, V., Hinton, G.E.: Rectified linear units improve restricted boltzmann machines. In: Proceedings of the 27th International Conference on Machine Learning (ICML-2010), pp. 807–814 (2010)
58.
Zurück zum Zitat He, K., Zhang, X., Ren, S., Sun, J.: Deep residual learning for image recognition He, K., Zhang, X., Ren, S., Sun, J.: Deep residual learning for image recognition
59.
Zurück zum Zitat Iandola, F.N., Han, S., Moskewicz, M.W., Ashraf, K., Dally, W.J., Keutzer, K.: SqueezeNet: AlexNet-level accuracy with 50x fewer parameters and \(<\)0.5 MB model size. arXiv:1602.07360 (2016) Iandola, F.N., Han, S., Moskewicz, M.W., Ashraf, K., Dally, W.J., Keutzer, K.: SqueezeNet: AlexNet-level accuracy with 50x fewer parameters and \(<\)0.5 MB model size. arXiv:​1602.​07360 (2016)
60.
Zurück zum Zitat Yosinski, J., Clune, J., Bengio, Y., Lipson, H.: How transferable are features in deep neural networks? In: NIPS, pp. 3320–3328 (2014) Yosinski, J., Clune, J., Bengio, Y., Lipson, H.: How transferable are features in deep neural networks? In: NIPS, pp. 3320–3328 (2014)
61.
Zurück zum Zitat Yang, C.H.H., et al.: A novel hybrid machine learning model for auto-classification of retinal diseases. arXiv preprint arXiv:1806.06423 (2018) Yang, C.H.H., et al.: A novel hybrid machine learning model for auto-classification of retinal diseases. arXiv preprint arXiv:​1806.​06423 (2018)
62.
Zurück zum Zitat Chang, C.C., Lin, C.J.: LIBSVM: a library for support vector machines. TIST 2, 27 (2011)CrossRef Chang, C.C., Lin, C.J.: LIBSVM: a library for support vector machines. TIST 2, 27 (2011)CrossRef
63.
Zurück zum Zitat Zhou, B., Khosla, A., Lapedriza, A., Oliva, A., Torralba, A.: Learning deep features for discriminative localization. In: CVPR (2016) Zhou, B., Khosla, A., Lapedriza, A., Oliva, A., Torralba, A.: Learning deep features for discriminative localization. In: CVPR (2016)
Metadaten
Titel
Auto-classification of Retinal Diseases in the Limit of Sparse Data Using a Two-Streams Machine Learning Model
verfasst von
C.-H. Huck Yang
Fangyu Liu
Jia-Hong Huang
Meng Tian
M. D. I-Hung Lin
Yi Chieh Liu
Hiromasa Morikawa
Hao-Hsiang Yang
Jesper Tegnèr
Copyright-Jahr
2019
DOI
https://doi.org/10.1007/978-3-030-21074-8_28

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