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2017 | OriginalPaper | Buchkapitel

Chemical Composition Effect of Sol-Gel Derived Bioactive Glass Over Bioactivity Behavior

verfasst von : L. A. Quintero, D. M. Escobar

Erschienen in: Proceedings of the 3rd Pan American Materials Congress

Verlag: Springer International Publishing

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Abstract

Bioactive glasses (BG) are a group of inorganic materials widely used in Bone Tissue Engineering (BTE). These biomaterials react with body fluids resulting in the formation of bone like apatite layer. In this study, sol-gel derived bioactive glass was synthesized in the SiO₂-CaO-P₂O₅ system according to augmented constrained mixture experimental design, with percentage restrictions for each oxide as follows: 58 ≤ SiO₂ ≤ 70; 6 ≤ P₂O₅ ≤ 9 and 24 ≤ CaO ≤ 34. BG were conformed into short-bulk cylinders and immersed in Simulated Body Fluid (SBF) solution for 7 and 14 days in order to carry out bioactivity tests. Apatite layer formation was confirmed by Scanning Electron Microscopy (SEM) and Energy Dispersive X-ray Analysis (EDX). The results showed apatite layer formation depended on BG chemical composition proved with p-values from ANOVA analysis below 0.05 indicating factors significance over the response. The formed apatite layer presented a Ca/P ratio similar to bone apatite, this result is appropriate for biomaterials used in BTE.

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Titel: Chemical Composition Effect of Sol-Gel Derived Bioactive Glass Over Bioactivity Behavior
verfasst von: L. A. Quintero
D. M. Escobar
Verlag: Springer International Publishing
Buch: Proceedings of the 3rd Pan American Materials Congress
Print ISBN: 978-3-319-52131-2

Electronic ISBN: 978-3-319-52132-9

Copyright-Jahr: 2017
DOI: https://doi.org/10.1007/978-3-319-52132-9_2

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