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Erschienen in:
2016 | OriginalPaper | Buchkapitel
Conductance Dynamics to Monitor and Control Cell Electropermeabilization
verfasst von : J. Teissié
Erschienen in: 1st World Congress on Electroporation and Pulsed Electric Fields in Biology, Medicine and Food & Environmental Technologies
Verlag: Springer Singapore
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Membrane electropermeabilization is observed when electric pulses over a critical strength are delivered on a cell suspension. This is associated with a time dependent change in the suspension conductance. The magnitude and the kinetics of the conductivity changes can be used to get access to the molecular event supporting the membrane electropermeabilization. In Bioprocesses, where extraction results from electropermeabilization, the control of the conductivity change of the cell suspension allows the definition of optimized safe conditions.