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Erschienen in: Journal of Nanoparticle Research 4/2019

01.04.2019 | Research Paper

Correlation between the rate of silver nanoparticle oxidation and their biological activity: the role of the capping agent

verfasst von: Yu.A. Krutyakov, A.A. Kudrinskiy, P.M. Zherebin, G.V. Lisichkin

Erschienen in: Journal of Nanoparticle Research | Ausgabe 4/2019

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Abstract

The correlation between the chemical nature of capping agents used to prepare colloidal silver dispersions and kinetic characteristics of the process of oxidation of the dispersed phase (spherical silver nanoparticles, 2–50 nm in diameter) by hydrogen peroxide was studied for the first time. The well-pronounced correlation between the oxidative dissolution rate and the biological activity of silver dispersions was revealed with respect to the inhibition of the growth of the Saccharomyces cerevisiae yeast. The biological activity of nanosilver dispersions was found to be primarily controlled by the rate of generation of silver ions while the chemical nature of the capping agent defined the rate of generation of silver ions, thus showing an effective way to control the biological action of medications based on silver nanoparticles by varying the nature of the capping agent.

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Metadaten
Titel
Correlation between the rate of silver nanoparticle oxidation and their biological activity: the role of the capping agent
verfasst von
Yu.A. Krutyakov
A.A. Kudrinskiy
P.M. Zherebin
G.V. Lisichkin
Publikationsdatum
01.04.2019
Verlag
Springer Netherlands
Erschienen in
Journal of Nanoparticle Research / Ausgabe 4/2019
Print ISSN: 1388-0764
Elektronische ISSN: 1572-896X
DOI
https://doi.org/10.1007/s11051-019-4495-4

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