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2009 | OriginalPaper | Buchkapitel

19. Digital Health and Bio-Medical Packaging

verfasst von : Lei Mercado, James K. Carney, Ph.D., Michael J. Ebert, Ph.D., Scott A. Hareland, Ph.D., Rashid Bashir, Ph.D.

Erschienen in: Materials for Advanced Packaging

Verlag: Springer US

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Abstract

This chapter reviews the healthcare trends and implications, as well as electronic packaging applications in implantable devices, pacing leads, bio-medical sensors, and point-of-care sensors. Each presents unique opportunities and challenges for electronic packaging and materials.

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Literatur
1.
Zurück zum Zitat Williams DF, The Williams Dictionary of Biomaterials (Liverpool, UK: Liverpool University Press, 1999), 40 Williams DF, The Williams Dictionary of Biomaterials (Liverpool, UK: Liverpool University Press, 1999), 40
2.
Zurück zum Zitat Bisping HJ and Rupp H. A new permanent transvenous electrode for fixation in the atrium. In Watanabe Y (ed), Proceedings of the Vth International Symposium on Cardiac Pacing. Amsterdam, Exerpta Medica, pp. 543–547, 1977 Bisping HJ and Rupp H. A new permanent transvenous electrode for fixation in the atrium. In Watanabe Y (ed), Proceedings of the Vth International Symposium on Cardiac Pacing. Amsterdam, Exerpta Medica, pp. 543–547, 1977
3.
Zurück zum Zitat Citron P and Dickhudt E. US Patent No. 3959502, Endocardial electrode. 1976 Citron P and Dickhudt E. US Patent No. 3959502, Endocardial electrode. 1976
4.
Zurück zum Zitat Anderson JA. Inflammatory response to implants. ASAIO II(2):101–107, 1988CrossRef Anderson JA. Inflammatory response to implants. ASAIO II(2):101–107, 1988CrossRef
5.
Zurück zum Zitat Chardack W, Gage A and Greatbatch W. Correction of complete heart block by a self contained and subcutaneously implanted pacemaker. J Thorac Cardiovasc Surg 42:814, 1961 Chardack W, Gage A and Greatbatch W. Correction of complete heart block by a self contained and subcutaneously implanted pacemaker. J Thorac Cardiovasc Surg 42:814, 1961
6.
Zurück zum Zitat Dolezel B, Adamirova L, Naprstek A and Vondracek P. In vivo degradation of polymers. I. Change of mechanical properties in polyethylene pacemaker lead insulations during long-term implantation in the human body. Biomaterials, 10(2):96–100, 1989CrossRef Dolezel B, Adamirova L, Naprstek A and Vondracek P. In vivo degradation of polymers. I. Change of mechanical properties in polyethylene pacemaker lead insulations during long-term implantation in the human body. Biomaterials, 10(2):96–100, 1989CrossRef
7.
Zurück zum Zitat Wasserbauer R, Beranova M, Vancurova D and Dolezel B. Biodegradation of polyethylene foils by bacterial and liver homogenates. Biomaterials, 11(l):36–40, 1990CrossRef Wasserbauer R, Beranova M, Vancurova D and Dolezel B. Biodegradation of polyethylene foils by bacterial and liver homogenates. Biomaterials, 11(l):36–40, 1990CrossRef
8.
Zurück zum Zitat Byrd CL, McArthur W, Stokes K, Sivina M, Yahr WZ and Greenberg J. Implant experience with unipolar polyurethane pacing leads. PACE, 6(5):868–882, 1983 Byrd CL, McArthur W, Stokes K, Sivina M, Yahr WZ and Greenberg J. Implant experience with unipolar polyurethane pacing leads. PACE, 6(5):868–882, 1983
9.
Zurück zum Zitat Zhao Q, Topham N, Anderson JM, Hiltner A, Loden G and Payet CR. Foreign-body giant cells and polyurethane biostability: In vivo correlation of cell adhesion and surface cracking. J Biomed Mater Res 25:177–183, 1991CrossRef Zhao Q, Topham N, Anderson JM, Hiltner A, Loden G and Payet CR. Foreign-body giant cells and polyurethane biostability: In vivo correlation of cell adhesion and surface cracking. J Biomed Mater Res 25:177–183, 1991CrossRef
10.
Zurück zum Zitat Zhao Q, McNally AK, Rubin KR, Reiner M, Wu Y, Rose-Caprara V, Anderson JM, Hiltner A, Urbanski P and Stokes K. Human plasma α2-macroglobulin promotes in vitro stress cracking of Pellethane 2363-80A: In vivo and in vitro correlations. J Biomed Mater Res In Press Zhao Q, McNally AK, Rubin KR, Reiner M, Wu Y, Rose-Caprara V, Anderson JM, Hiltner A, Urbanski P and Stokes K. Human plasma α2-macroglobulin promotes in vitro stress cracking of Pellethane 2363-80A: In vivo and in vitro correlations. J Biomed Mater Res In Press
11.
Zurück zum Zitat Beanlands DS, Akyurekli Y and Keon WJ. Prednisone in the management of exit block. In Meere C (ed), Proceedings of the VIth World Symposium on Cardiac Pacing, Montreal, PACESYMP, 1979, Chapter 80-3 Beanlands DS, Akyurekli Y and Keon WJ. Prednisone in the management of exit block. In Meere C (ed), Proceedings of the VIth World Symposium on Cardiac Pacing, Montreal, PACESYMP, 1979, Chapter 80-3
12.
Zurück zum Zitat Irnich W. Physikalische Uberlegungen zur elektrostimulation. Biomedizin Technik 3:97–104, 1973CrossRef Irnich W. Physikalische Uberlegungen zur elektrostimulation. Biomedizin Technik 3:97–104, 1973CrossRef
13.
Zurück zum Zitat Barold SS, Ong IS and Heile RA. Matching characteristics of pulse generator and electrodes. A clinicians concept of input and source impedance and their effect on demand function. In Meere C (ed), Proceedings of the VIth World Symposium on Cardiac Pacing, Montreal, PACESYMP, 1979, Chapter 34-3 Barold SS, Ong IS and Heile RA. Matching characteristics of pulse generator and electrodes. A clinicians concept of input and source impedance and their effect on demand function. In Meere C (ed), Proceedings of the VIth World Symposium on Cardiac Pacing, Montreal, PACESYMP, 1979, Chapter 34-3
14.
Zurück zum Zitat Amundson D, McArthur W, MacCarter D and Mosharrafa M. Porous electrode-tissue interface. In C Meere (ed), Proceedings of the VIth World Symposium on Cardiac Pacing Montreal, PACESYMP, Chapter 29-16 Amundson D, McArthur W, MacCarter D and Mosharrafa M. Porous electrode-tissue interface. In C Meere (ed), Proceedings of the VIth World Symposium on Cardiac Pacing Montreal, PACESYMP, Chapter 29-16
15.
Zurück zum Zitat Wilson GJ, MacGregor DC, Bobyn JD, Lixfeld W, Pillar RM, Miller SL and Silver MD. Tissue response to porous-surfaced electrodes: Basis for a new atrial lead design. In C Meere (ed), Proceedings of the VIth World Symposium on Cardiac Pacing, Montreal, PACESYMP, Chapter 29-12 Wilson GJ, MacGregor DC, Bobyn JD, Lixfeld W, Pillar RM, Miller SL and Silver MD. Tissue response to porous-surfaced electrodes: Basis for a new atrial lead design. In C Meere (ed), Proceedings of the VIth World Symposium on Cardiac Pacing, Montreal, PACESYMP, Chapter 29-12
16.
Zurück zum Zitat Beck-Jansen P, Schuller H and Winther-Rasmussen S. Vitreous carbon electrodes in endocardial pacing. In C Meere (ed), Proceedings of the VIth World Symposium on Cardiac Pacing, Montreal, PACESYMP, Chapter 29-9 Beck-Jansen P, Schuller H and Winther-Rasmussen S. Vitreous carbon electrodes in endocardial pacing. In C Meere (ed), Proceedings of the VIth World Symposium on Cardiac Pacing, Montreal, PACESYMP, Chapter 29-9
17.
Zurück zum Zitat Schaldach M, Bolz A, Breme J, Hubmann M and Hardt R. Acute and long-term sensing and pacing performance of pacemaker leads having titanium nitride electrode tips. In Antonioli E, Aubert AE and Ector H (eds), Pacemaker Leads 1991, Amsterdam, Elsevier, 1991, pp. 441–450 Schaldach M, Bolz A, Breme J, Hubmann M and Hardt R. Acute and long-term sensing and pacing performance of pacemaker leads having titanium nitride electrode tips. In Antonioli E, Aubert AE and Ector H (eds), Pacemaker Leads 1991, Amsterdam, Elsevier, 1991, pp. 441–450
18.
Zurück zum Zitat Del Bufalo AGA, Schlaepfer J, Fromer M and Kappenberger L. Acute and long-term ventricular stimulation with a new iridium oxide-coated electrode. PACE 16(6):1240–1244, 1993 Del Bufalo AGA, Schlaepfer J, Fromer M and Kappenberger L. Acute and long-term ventricular stimulation with a new iridium oxide-coated electrode. PACE 16(6):1240–1244, 1993
19.
Zurück zum Zitat Stokes KB, Graf JE and Wiebusch WA. Drug-eluting electrodes-improved pacemaker performance. In Potvin AR and Potvin JH (eds), Frontiers of Engineering in Health Care-1982. Proceedings, Fourth Annual Conference IEEE Engineering in Medicine and Biology Society, pp. 499–502, 1982 Stokes KB, Graf JE and Wiebusch WA. Drug-eluting electrodes-improved pacemaker performance. In Potvin AR and Potvin JH (eds), Frontiers of Engineering in Health Care-1982. Proceedings, Fourth Annual Conference IEEE Engineering in Medicine and Biology Society, pp. 499–502, 1982
20.
Zurück zum Zitat Stokes KB, Bornzin GA. and Wiebusch, WA. A steroid-eluting, low-threshold, low-polarizing electrode. In Steinbach K (ed) , Cardiac Pacing, Darmstadt, Steinkopff Verlag, pp. 369–376, 1983 Stokes KB, Bornzin GA. and Wiebusch, WA. A steroid-eluting, low-threshold, low-polarizing electrode. In Steinbach K (ed) , Cardiac Pacing, Darmstadt, Steinkopff Verlag, pp. 369–376, 1983
21.
Zurück zum Zitat Mond H and Stokes K. The Electrode-Tissue Interface: The Revolutionary Role of Steroid Elution. PACE 15(l):95–107, 1992 Mond H and Stokes K. The Electrode-Tissue Interface: The Revolutionary Role of Steroid Elution. PACE 15(l):95–107, 1992
22.
Zurück zum Zitat Stokes K and Anderson J. Low Threshold Leads: The Effect Of Steroid Elution. In Antonioli GE (ed), Pacemaker Leads, Amsterdam, Elsevier, 537–542, 1991 Stokes K and Anderson J. Low Threshold Leads: The Effect Of Steroid Elution. In Antonioli GE (ed), Pacemaker Leads, Amsterdam, Elsevier, 537–542, 1991
23.
Zurück zum Zitat Thevenet A, Hodges PC and Lillehei CW. Use of myocardial electrode inserted percutaneously for control of complete atrioventricular block by artificial pacemaker. Dis Chest 34:621–631, 1958 Thevenet A, Hodges PC and Lillehei CW. Use of myocardial electrode inserted percutaneously for control of complete atrioventricular block by artificial pacemaker. Dis Chest 34:621–631, 1958
24.
Zurück zum Zitat Dawson WW (ed). Electrode materials study, contract number NIH-71-2286, Tenth Quarterly Report, Nov. 1973–Jan. 1974 Dawson WW (ed). Electrode materials study, contract number NIH-71-2286, Tenth Quarterly Report, Nov. 1973–Jan. 1974
25.
Zurück zum Zitat Johnson PF, Bernstein JJ, Hunter G, Dawson WW and Hench LL. An in vitro and in vivo analysis of anodized tantalum capacitive electrodes: corrosion response, physiology and histology. J Biomed Mater Res 11:637–656, 1977CrossRef Johnson PF, Bernstein JJ, Hunter G, Dawson WW and Hench LL. An in vitro and in vivo analysis of anodized tantalum capacitive electrodes: corrosion response, physiology and histology. J Biomed Mater Res 11:637–656, 1977CrossRef
26.
Zurück zum Zitat Maiolino P, Del Bene P, Cecci A, Cappelletti F, Pauletti M, Al Bunni M and Audoglio R. Titanium oxide electrode: 60 Months clinical experience of low energy pacing. In Antonioli GE, Aubert AE and Ector H (eds), Pacemaker Leads 1991, Amsterdam, Elsevier, pp. 491–496, 1991 Maiolino P, Del Bene P, Cecci A, Cappelletti F, Pauletti M, Al Bunni M and Audoglio R. Titanium oxide electrode: 60 Months clinical experience of low energy pacing. In Antonioli GE, Aubert AE and Ector H (eds), Pacemaker Leads 1991, Amsterdam, Elsevier, pp. 491–496, 1991
27.
Zurück zum Zitat Audoglio R and Gatti AM. Non-stoichiometric titanium oxide: Why is it a so effective material for low energy pacing? In Antonioli GE, Aubert AE and Ector H (eds), Pacemaker Leads 1991, Amsterdam, Elsevier, pp. 491–496, 1991 Audoglio R and Gatti AM. Non-stoichiometric titanium oxide: Why is it a so effective material for low energy pacing? In Antonioli GE, Aubert AE and Ector H (eds), Pacemaker Leads 1991, Amsterdam, Elsevier, pp. 491–496, 1991
28.
Zurück zum Zitat Pandolfino JE, Richter JE, Ours T, Guardino JM, Chapman J, and Kahrilas PJ. Ambulatory esophageal pH monitoring using a wireless system. Am J Gastroenterol 98:740–749, 2003CrossRef Pandolfino JE, Richter JE, Ours T, Guardino JM, Chapman J, and Kahrilas PJ. Ambulatory esophageal pH monitoring using a wireless system. Am J Gastroenterol 98:740–749, 2003CrossRef
29.
Zurück zum Zitat Najafi N and Ludomirsky A. Initial Animal Studies of a Wireless, Batteryless, MEMS Implant for Cardiovascular Applications. Biomedical Microdevices 6:61–65, 2004CrossRef Najafi N and Ludomirsky A. Initial Animal Studies of a Wireless, Batteryless, MEMS Implant for Cardiovascular Applications. Biomedical Microdevices 6:61–65, 2004CrossRef
30.
Zurück zum Zitat Stangel K, Kolnsberg S, Hammerschmidt D, Hosticka BJ, Trieu HK, and Mokwa W. A programmable intraocular CMOS pressure sensor system implant. IEEE J Solid-State Circuits 36:1094–1100, 2001CrossRef Stangel K, Kolnsberg S, Hammerschmidt D, Hosticka BJ, Trieu HK, and Mokwa W. A programmable intraocular CMOS pressure sensor system implant. IEEE J Solid-State Circuits 36:1094–1100, 2001CrossRef
31.
Zurück zum Zitat Steinhaus D, Reynolds DW, Gadler F, Kay GN, Hess MF, and Bennett T. Implant experience with an implantable hemodynamic monitor for the management of symptomatic heart failure. Pacing Clin Electrophysiol 28:747–53, 2005CrossRef Steinhaus D, Reynolds DW, Gadler F, Kay GN, Hess MF, and Bennett T. Implant experience with an implantable hemodynamic monitor for the management of symptomatic heart failure. Pacing Clin Electrophysiol 28:747–53, 2005CrossRef
32.
Zurück zum Zitat Chow AY, Chow VY, Packo K, Pollack J, Peyman G, and Schuchard R, The artificial silicon retina microchip for the treatment of vision loss from retinitis pigmentosa. Arch Ophthalmol 122:460–469, 2004CrossRef Chow AY, Chow VY, Packo K, Pollack J, Peyman G, and Schuchard R, The artificial silicon retina microchip for the treatment of vision loss from retinitis pigmentosa. Arch Ophthalmol 122:460–469, 2004CrossRef
33.
Zurück zum Zitat Liu W, McGucken E, Cavin R, Clements M, Vichienchom K, Demarco C, Humayun M, de Juan E, Weiland J, and Greenberg R. A retinal prosthesis to benefit the visually impaired. In Teodorescu N (ed), Intelligent System and Techniques in Rehabilitation Engineering, CRC Press, 99, pp. 31–87, 2000 Liu W, McGucken E, Cavin R, Clements M, Vichienchom K, Demarco C, Humayun M, de Juan E, Weiland J, and Greenberg R. A retinal prosthesis to benefit the visually impaired. In Teodorescu N (ed), Intelligent System and Techniques in Rehabilitation Engineering, CRC Press, 99, pp. 31–87, 2000
34.
Zurück zum Zitat D’Lima DD, Townsend CP, Arms SW, Morris BA, and Colwell CW. An Implantable Telemetry Device to Measure Intra-Articular Tibial Forces. J Bio-Mechanics 38:299–304, 2005. D’Lima DD, Townsend CP, Arms SW, Morris BA, and Colwell CW. An Implantable Telemetry Device to Measure Intra-Articular Tibial Forces. J Bio-Mechanics 38:299–304, 2005.
35.
Zurück zum Zitat Kirking B, Krevolin J, Townsend C, Colwell CW Jr, and D'Lima DD. A multiaxial force-sensing implantable tibial prosthesis. J Biomechanics 39:1744–1751, 2006CrossRef Kirking B, Krevolin J, Townsend C, Colwell CW Jr, and D'Lima DD. A multiaxial force-sensing implantable tibial prosthesis. J Biomechanics 39:1744–1751, 2006CrossRef
36.
Zurück zum Zitat Klonoff DC. Continuous glucose monitoring: roadmap for 21st century diabetes therapy. Diabetes Care 28:1231–1239, 2005CrossRef Klonoff DC. Continuous glucose monitoring: roadmap for 21st century diabetes therapy. Diabetes Care 28:1231–1239, 2005CrossRef
37.
Zurück zum Zitat Gross TM, Bode BW, Einhorn D, Kayne DM, Reed JH, White NH, and Mastrototaro JJ. Performance evaluation of the MiniMed continuous glucose monitoring system during patient home use. Diabetes Technol Ther 2:49–56, 2000CrossRef Gross TM, Bode BW, Einhorn D, Kayne DM, Reed JH, White NH, and Mastrototaro JJ. Performance evaluation of the MiniMed continuous glucose monitoring system during patient home use. Diabetes Technol Ther 2:49–56, 2000CrossRef
38.
Zurück zum Zitat Garg SK, Schwartz S, and Edelman SV. Improved Glucose excursions using an implantable real-time continuous glucose sensor in adults with type 1 diabetes. Diabetes Care 27:734–738, 2004CrossRef Garg SK, Schwartz S, and Edelman SV. Improved Glucose excursions using an implantable real-time continuous glucose sensor in adults with type 1 diabetes. Diabetes Care 27:734–738, 2004CrossRef
39.
Zurück zum Zitat Bashir R. BioMEMS: State of the art in detection and future prospects, Adv Drug Delivery Rev 56:1565–1586, 2004CrossRef Bashir R. BioMEMS: State of the art in detection and future prospects, Adv Drug Delivery Rev 56:1565–1586, 2004CrossRef
40.
Zurück zum Zitat Toner M and Irimia D. Blood-on-a-Chip. Annu Rev Biomed Eng 7:77–103, 2005CrossRef Toner M and Irimia D. Blood-on-a-Chip. Annu Rev Biomed Eng 7:77–103, 2005CrossRef
41.
Zurück zum Zitat Lee K. The development of highly functional cartridge for rapid detection of microbial contaminants. MS Thesis, Purdue University, 2006 Lee K. The development of highly functional cartridge for rapid detection of microbial contaminants. MS Thesis, Purdue University, 2006
Metadaten
Titel
Digital Health and Bio-Medical Packaging
verfasst von
Lei Mercado
James K. Carney, Ph.D.
Michael J. Ebert, Ph.D.
Scott A. Hareland, Ph.D.
Rashid Bashir, Ph.D.
Copyright-Jahr
2009
Verlag
Springer US
DOI
https://doi.org/10.1007/978-0-387-78219-5_19