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Erschienen in:
A Brief Introduction to Microfluidics Kapitel lesen Erstes Kapitel lesen

2016 | OriginalPaper | Buchkapitel

10. Drug Delivery Through Microneedles

verfasst von : R. Luttge

Erschienen in: Microsystems for Pharmatechnology

Verlag: Springer International Publishing

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Abstract

Drug delivery through microneedles is a new form of a pharmaceutical dosage system. While single microneedles have been clinically applied already, the out-of-plane integration of a multitude of microneedles in a pharmaceutical patch is a disruptive technology. To take advantage of micro- and nanofluidics, such active patches utilize microneedle array (MNA) technology. MNAs are microsystems that adopt their technical uniqueness by the choice of a fabrication technology. MNAs can be made of solid, hollow, porous, or dissolvable materials in a cost-effective manner by the so-called MEMS technology. However, key to their success will be a proof-of-concept in the clinic, which must demonstrate that the intradermal (nano)release of drugs and vaccines serve an unmet medical need. In this chapter, we discuss recently established MNA platform technologies and by means of a case study we assess novel opportunities for MNAs in drug and vaccine delivery arising from this novel skin interface.

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Vorheriges Kapitel Respiratory Drug Delivery
Nächstes Kapitel Organ on Chip
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Metadaten
Titel
Drug Delivery Through Microneedles
verfasst von
R. Luttge
Copyright-Jahr
2016
Buch
Microsystems for Pharmatechnology

Print ISBN: 978-3-319-26918-4

Electronic ISBN: 978-3-319-26920-7

Copyright-Jahr: 2016

DOI
https://doi.org/10.1007/978-3-319-26920-7_10

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