Effect of Insertion Force for Successful Penetration of a Conical Shaped Microneedle into the Skin

Microneedles and microneedle-related technologies are the present trends in medical science which are voraciously being investigated by the research community towards various therapeutic and medical diagnostic applications, since they are treated and also to be considered as painless methodology of administering vaccines. Apart from that these microneedles clearly aids in mitigating the potential risk of infections and ailments related when needle transfusions when the medicine is transmitted into the body. Microneedles have gained much upfront and considered to be a novel way for administering drugs and vaccines through transdermal drug delivery. This particular area primarily mends upon the design and analysis of silicon and stainless steel based hollow conical microneedles for transdermal drug delivery (TDD). The effect of axial and transverse load on a microneedle has been investigated along with the mechanical properties. The analysis predicts that the resultant stresses due to applied bending and axial loads are in the safe & comfort desired range. The primary work was focused on the conical-shaped hollow needles of micron-sized dimensions. In this paper simulation studies are carried out on the stress analysis along with displacement parameters.