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2015 | OriginalPaper | Buchkapitel

Enabling Technologies to Advance Microbial Isoprenoid Production

verfasst von : Yun Chen, Yongjin J. Zhou, Verena Siewers, Jens Nielsen

Erschienen in: Biotechnology of Isoprenoids

Verlag: Springer International Publishing

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Abstract

Microbial production of isoprenoids provides an attractive alternative to biomass extraction and chemical synthesis. Although widespread research aims for isoprenoid biosynthesis, it is still in its infancy in terms of delivering commercial products. Large barriers remain in realizing a cost-competitive process, for example, developing an optimal microbial cell factory. Here, we summarize the many tools and methods that have been developed in the metabolic engineering of isoprenoid production, with the advent of systems biology and synthetic biology, and discuss how these technologies advance to accelerate the design–build–test engineering cycle to obtain optimum microbial systems. It is anticipated that innovative combinations of new and existing technologies will continue to emerge, which will enable further development of microbial cell factories for commercial isoprenoid production.

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Vorheriges Kapitel Cytochromes P450 for Terpene Functionalisation and Metabolic Engineering

Nächstes Kapitel Metabolic Engineering of Higher Plants and Algae for Isoprenoid Production

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Titel: Enabling Technologies to Advance Microbial Isoprenoid Production
verfasst von: Yun Chen
Yongjin J. Zhou
Verena Siewers
Jens Nielsen
Verlag: Springer International Publishing
Buch: Biotechnology of Isoprenoids
Print ISBN: 978-3-319-20106-1

Electronic ISBN: 978-3-319-20107-8

Copyright-Jahr: 2015
DOI: https://doi.org/10.1007/10_2014_284

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