Skip to main content

2024 | OriginalPaper | Buchkapitel

Explainable Artificial Intelligence for Deep Learning Models in Diagnosing Brain Tumor Disorder

verfasst von : Kamini Lamba, Shalli Rani

Erschienen in: Micro-Electronics and Telecommunication Engineering

Verlag: Springer Nature Singapore

Aktivieren Sie unsere intelligente Suche, um passende Fachinhalte oder Patente zu finden.

search-config
loading …

Abstract

Deep neural networks (DNNs) have shown great potential in diagnosing brain tumor disorder, but their decision-making processes can be difficult to interpret, leading to concerns about their reliability and safety. This paper presents overview of explainable artificial intelligence techniques which have been developed to improve the interpretability and transparency of DNNs and have been applied to diagnostic systems for such disorders. Based on the utilized framework of explainable artificial intelligence (XAI) in collaboration with deep learning models, authors diagnosed brain tumor with the help of convolutional neural network and interpreted its outcomes with the help of numerical gradient-weighted class activation mapping (numGrad-CAM-CNN), therefore achieved highest accuracy of 97.11%. Thus, XAI can help healthcare professionals in understanding how a DNN arrived at a diagnosis, providing insights into the reasoning and decision-making processes of the model. XAI techniques can also help to identify biases in the data used to train the model and address potential ethical concerns. However, challenges remain in implementing XAI techniques in diagnostic systems, including the need for large, diverse datasets, and the development of user-friendly interfaces. Despite these challenges, the potential benefits for improving patient outcomes and increasing trust in AI-based medical systems make it a promising area of research.

Sie haben noch keine Lizenz? Dann Informieren Sie sich jetzt über unsere Produkte:

Springer Professional "Wirtschaft+Technik"

Online-Abonnement

Mit Springer Professional "Wirtschaft+Technik" erhalten Sie Zugriff auf:

  • über 102.000 Bücher
  • über 537 Zeitschriften

aus folgenden Fachgebieten:

  • Automobil + Motoren
  • Bauwesen + Immobilien
  • Business IT + Informatik
  • Elektrotechnik + Elektronik
  • Energie + Nachhaltigkeit
  • Finance + Banking
  • Management + Führung
  • Marketing + Vertrieb
  • Maschinenbau + Werkstoffe
  • Versicherung + Risiko

Jetzt Wissensvorsprung sichern!

Springer Professional "Technik"

Online-Abonnement

Mit Springer Professional "Technik" erhalten Sie Zugriff auf:

  • über 67.000 Bücher
  • über 390 Zeitschriften

aus folgenden Fachgebieten:

  • Automobil + Motoren
  • Bauwesen + Immobilien
  • Business IT + Informatik
  • Elektrotechnik + Elektronik
  • Energie + Nachhaltigkeit
  • Maschinenbau + Werkstoffe




 

Jetzt Wissensvorsprung sichern!

Literatur
1.
Zurück zum Zitat Louis DN, Perry A, Reifenberger G, Von Deimling A, Figarella-Branger D, Cavenee WK, Ohgaki H, Wiestler OD, Kleihues P, Ellison DW (2016) The 2016 world health organization classification of tumors of the central nervous system: a summary. Acta Neuropathologica 131:803–820 Louis DN, Perry A, Reifenberger G, Von Deimling A, Figarella-Branger D, Cavenee WK, Ohgaki H, Wiestler OD, Kleihues P, Ellison DW (2016) The 2016 world health organization classification of tumors of the central nervous system: a summary. Acta Neuropathologica 131:803–820
2.
Zurück zum Zitat LeCun Y, Bengio Y, Hinton G (2015) Deep learning. Nature 521(7553):436–444 LeCun Y, Bengio Y, Hinton G (2015) Deep learning. Nature 521(7553):436–444
3.
Zurück zum Zitat Bengio Y, Courville A, Vincent P (2013) Representation learning: a review and new perspectives. IEEE Trans Pattern Anal Mach Intell 35(8):1798–1828CrossRef Bengio Y, Courville A, Vincent P (2013) Representation learning: a review and new perspectives. IEEE Trans Pattern Anal Mach Intell 35(8):1798–1828CrossRef
4.
Zurück zum Zitat Bengio Y et al. (2009) Learning deep architectures for AI, Foundations and trends® in Machine Learning 2(1):1–127 Bengio Y et al. (2009) Learning deep architectures for AI, Foundations and trends® in Machine Learning 2(1):1–127
5.
Zurück zum Zitat Rumelhart DE, Hinton GE, Williams RJ (1986) Learning representations by back-propagating errors. Nature 323(6088):533–536 Rumelhart DE, Hinton GE, Williams RJ (1986) Learning representations by back-propagating errors. Nature 323(6088):533–536
6.
Zurück zum Zitat Esteva A, Kuprel B, Novoa RA, Ko J, Swetter SM, Blau HM, Thrun S (2017) Dermatologist-level classification of skin cancer with deep neural networks. Nature 542(7639):115–118 Esteva A, Kuprel B, Novoa RA, Ko J, Swetter SM, Blau HM, Thrun S (2017) Dermatologist-level classification of skin cancer with deep neural networks. Nature 542(7639):115–118
7.
Zurück zum Zitat Miotto R, Wang F, Wang S, Jiang X, Dudley JT (2018) Deep learning for healthcare: review, opportunities and challenges. Brief Bioinform 19(6):1236–1246CrossRef Miotto R, Wang F, Wang S, Jiang X, Dudley JT (2018) Deep learning for healthcare: review, opportunities and challenges. Brief Bioinform 19(6):1236–1246CrossRef
8.
Zurück zum Zitat Ahmed S, Nobel SN, Ullah O (2023) An effective deep CNN model for multiclass brain tumor detection using mri images and shap explainability. In: 2023 International conference on electrical, computer and communication engineering (ECCE), IEEE, 2023, pp 1–6 Ahmed S, Nobel SN, Ullah O (2023) An effective deep CNN model for multiclass brain tumor detection using mri images and shap explainability. In: 2023 International conference on electrical, computer and communication engineering (ECCE), IEEE, 2023, pp 1–6
9.
Zurück zum Zitat Jin W, Li X, Fatehi M, Hamarneh G (2023) Generating post-hoc explanation from deep neural networks for multi-modal medical image analysis tasks. MethodsX 10:102009CrossRef Jin W, Li X, Fatehi M, Hamarneh G (2023) Generating post-hoc explanation from deep neural networks for multi-modal medical image analysis tasks. MethodsX 10:102009CrossRef
10.
Zurück zum Zitat Kamnitsas K, Ledig C, Newcombe VF, Simpson JP, Kane AD, Menon DK, Rueckert D, Glocker B (2017) Efficient multi-scale 3d CNN with fully connected CRF for accurate brain lesion segmentation. Med Image Anal 36:61–78CrossRef Kamnitsas K, Ledig C, Newcombe VF, Simpson JP, Kane AD, Menon DK, Rueckert D, Glocker B (2017) Efficient multi-scale 3d CNN with fully connected CRF for accurate brain lesion segmentation. Med Image Anal 36:61–78CrossRef
11.
Zurück zum Zitat Bechelli S (2022) Computer-aided cancer diagnosis via machine learning and deep learning: a comparative review, arXiv preprint arXiv:2210.11943 Bechelli S (2022) Computer-aided cancer diagnosis via machine learning and deep learning: a comparative review, arXiv preprint arXiv:​2210.​11943
12.
Zurück zum Zitat Sharma S, Gupta S, Gupta D, Juneja A, Khatter H, Malik S, Bitsue ZK (2022) Deep learning model for automatic classification and prediction of brain tumor. J Sens Sharma S, Gupta S, Gupta D, Juneja A, Khatter H, Malik S, Bitsue ZK (2022) Deep learning model for automatic classification and prediction of brain tumor. J Sens
13.
Zurück zum Zitat Kukreja V, Ahuja S et al. (2021) Recognition and classification of mathematical expressions using machine learning and deep learning methods. In: 2021 9th International conference on reliability, infocom technologies and optimization (Trends and Future Directions) (ICRITO), IEEE, 2021, pp 1–5 Kukreja V, Ahuja S et al. (2021) Recognition and classification of mathematical expressions using machine learning and deep learning methods. In: 2021 9th International conference on reliability, infocom technologies and optimization (Trends and Future Directions) (ICRITO), IEEE, 2021, pp 1–5
14.
Zurück zum Zitat Thapa K, Khan H, Singh TG, Kaur A (2021) Traumatic brain injury: mechanistic insight on pathophysiology and potential therapeutic targets. J Mol Neurosci 71(9):1725–1742CrossRef Thapa K, Khan H, Singh TG, Kaur A (2021) Traumatic brain injury: mechanistic insight on pathophysiology and potential therapeutic targets. J Mol Neurosci 71(9):1725–1742CrossRef
15.
Zurück zum Zitat Rehni AK, Singh TG, Jaggi AS, Singh N (2008) Pharmacological preconditioning of the brain: a possible interplay between opioid and calcitonin gene related peptide transduction systems. Pharmacol Reports 60(6):904 Rehni AK, Singh TG, Jaggi AS, Singh N (2008) Pharmacological preconditioning of the brain: a possible interplay between opioid and calcitonin gene related peptide transduction systems. Pharmacol Reports 60(6):904
16.
Zurück zum Zitat Kamini, Rani S (2023) Artificial intelligence and machine learning models for diagnosing neurodegenerative disorders. In: Data analysis for neurodegenerative disorders, Springer, pp 15–48 Kamini, Rani S (2023) Artificial intelligence and machine learning models for diagnosing neurodegenerative disorders. In: Data analysis for neurodegenerative disorders, Springer, pp 15–48
17.
Zurück zum Zitat Ribeiro MT, Singh S, Guestrin C (2016) why should i trust you?” explaining the predictions of any classifier. In: Proceedings of the 22nd ACM SIGKDD international conference on knowledge discovery and data mining, 2016, pp 1135–1144 Ribeiro MT, Singh S, Guestrin C (2016) why should i trust you?” explaining the predictions of any classifier. In: Proceedings of the 22nd ACM SIGKDD international conference on knowledge discovery and data mining, 2016, pp 1135–1144
18.
Zurück zum Zitat Lundberg SM, Lee S-I (2017) A unified approach to interpreting model predictions. In: Advances in neural information processing systems, pp 30 Lundberg SM, Lee S-I (2017) A unified approach to interpreting model predictions. In: Advances in neural information processing systems, pp 30
19.
Zurück zum Zitat Sundararajan M, Taly A, Yan Q (2017) Axiomatic attribution for deep networks. In: International conference on machine learning, PMLR, 2017, pp 3319–3328 Sundararajan M, Taly A, Yan Q (2017) Axiomatic attribution for deep networks. In: International conference on machine learning, PMLR, 2017, pp 3319–3328
20.
Zurück zum Zitat Selvaraju RR, Cogswell M, Das A, Vedantam R, Parikh D, Batra D (2017) Grad-cam: visual explanations from deep networks via gradient-based localization. In: Proceedings of the IEEE international conference on computer vision, pp 618–626 Selvaraju RR, Cogswell M, Das A, Vedantam R, Parikh D, Batra D (2017) Grad-cam: visual explanations from deep networks via gradient-based localization. In: Proceedings of the IEEE international conference on computer vision, pp 618–626
21.
Zurück zum Zitat Pertzborn D, Arolt C, Ernst G, Lechtenfeld OJ, Kaesler J, Pelzel D, Guntinas-Lichius O, von Eggeling F, Hoffmann F (2022) Multi-class cancer subtyping in salivary gland carcinomas with maldi imaging and deep learning. Cancers 14(17):4342 Pertzborn D, Arolt C, Ernst G, Lechtenfeld OJ, Kaesler J, Pelzel D, Guntinas-Lichius O, von Eggeling F, Hoffmann F (2022) Multi-class cancer subtyping in salivary gland carcinomas with maldi imaging and deep learning. Cancers 14(17):4342
22.
Zurück zum Zitat Gaur L, Bhandari M, Razdan T, Mallik S, Zhao Z (2022) Explanation-driven deep learning model for prediction of brain tumour status using MRI image data. Front Genet 448 Gaur L, Bhandari M, Razdan T, Mallik S, Zhao Z (2022) Explanation-driven deep learning model for prediction of brain tumour status using MRI image data. Front Genet 448
23.
Zurück zum Zitat Park KH, Batbaatar E, Piao Y, Theera-Umpon N, Ryu KH (2021) Deep learning feature extraction approach for hematopoietic cancer subtype classification. Int J Environ Res Public Health 18(4):2197CrossRef Park KH, Batbaatar E, Piao Y, Theera-Umpon N, Ryu KH (2021) Deep learning feature extraction approach for hematopoietic cancer subtype classification. Int J Environ Res Public Health 18(4):2197CrossRef
24.
Zurück zum Zitat Marmolejo-Saucedo JA, Kose U (2022) Numerical grad-cam based explainable convolutional neural network for brain tumor diagnosis. Mobile Netw Appl 1–10 Marmolejo-Saucedo JA, Kose U (2022) Numerical grad-cam based explainable convolutional neural network for brain tumor diagnosis. Mobile Netw Appl 1–10
25.
Zurück zum Zitat Montavon G, Samek W, Mu¨ller K-R (2018) Methods for interpreting and understanding deep neural networks. Digital Signal Process 73:1–15 Montavon G, Samek W, Mu¨ller K-R (2018) Methods for interpreting and understanding deep neural networks. Digital Signal Process 73:1–15
26.
Metadaten
Titel
Explainable Artificial Intelligence for Deep Learning Models in Diagnosing Brain Tumor Disorder
verfasst von
Kamini Lamba
Shalli Rani
Copyright-Jahr
2024
Verlag
Springer Nature Singapore
DOI
https://doi.org/10.1007/978-981-99-9562-2_13

Neuer Inhalt