Functional biodynamics of human-body system: A mathematical axiomatics with functional learning and aging in life cycle

“Systems neuroergonomics” (Mau, J. In: R. Wang and X. Pan, editors, Advances in Cognitive Neurodynamics (V), chapter 59, pages 431–437, Springer Science+Business Media, Singapore, 2016) showed a separation of human-body system’s functional organization from its cellular material in order to open a holistic perspective that can comprise all body functions. This was achieved with a strictly hierarchical structure in drill-down from system’s functional whole to base functional elements. Implied multi-scale functional dynamics with coherent up-scaling were mathematically described in an axiomatic way, but the daily wake/sleep dynamics cover mainly anticipated functional challenges. Here, the theory is expanded to permit “functional learning” in the sense of adjustment of functional capacities to meet higher demand. “Functional aging” as a whole-body frailty is derived from biodynamic entropy that eventually drives the living to meet its inevitable destiny, death. The ages at which frailty begins to dominate can currently be obtained only from official life tables as population averages and are different for men and women, accordingly. The objective is to develop a mathematical theory in medicine from an axiomatic approach to phenomenological biodynamics, in which cognition is viewed as an embodied activity.