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2013 | OriginalPaper | Buchkapitel

Hairy Root Culture: Bioreactor Design and Process Intensification

verfasst von : Amanda R. Stiles, Chun-Zhao Liu

Erschienen in: Biotechnology of Hairy Root Systems

Verlag: Springer Berlin Heidelberg

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Abstract

The cultivation of hairy roots for the production of secondary metabolites offers numerous advantages; hairy roots have a fast growth rate, are genetically stable, and are relatively simple to maintain in phytohormone free media. Hairy roots provide a continuous source of secondary metabolites, and are useful for the production of chemicals for pharmaceuticals, cosmetics, and food additives. In order for hairy roots to be utilized on a commercial scale, it is necessary to scale-up their production. Over the last several decades, significant research has been conducted on the cultivation of hairy roots in various types of bioreactor systems. In this review, we discuss the advantages and disadvantages of various bioreactor systems, the major factors related to large-scale bioreactor cultures, process intensification technologies and overview the mathematical models and computer-aided methods that have been utilized for bioreactor design and development.

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Vorheriges Kapitel Effective Elicitors and Process Strategies for Enhancement of Secondary Metabolite Production in Hairy Root Cultures

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Titel: Hairy Root Culture: Bioreactor Design and Process Intensification
verfasst von: Amanda R. Stiles
Chun-Zhao Liu
Verlag: Springer Berlin Heidelberg
Buch: Biotechnology of Hairy Root Systems
Print ISBN: 978-3-642-39018-0

Electronic ISBN: 978-3-642-39019-7

Copyright-Jahr: 2013
DOI: https://doi.org/10.1007/10_2013_181

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