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Erschienen in: Quality of Life Research 6/2010

01.08.2010

Health-related quality of life in inflammatory bowel disease measured with the generic 15D instrument

verfasst von: Johanna Haapamäki, Risto P. Roine, Harri Sintonen, Ulla Turunen, Martti A. Färkkilä, Perttu E. T. Arkkila

Erschienen in: Quality of Life Research | Ausgabe 6/2010

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Abstract

Objectives

In many surveys, inflammatory bowel disease (IBD) has been shown to have a negative impact on health-related quality of life (HRQoL), especially when the disease is active. The purpose of this study was to compare a disease-specific HRQoL tool (Inflammatory Bowel Disease Questionnaire, IBDQ) and a generic HRQoL tool (15D) in a large cohort of IBD patients, to assess the ability of the 15D to detect differences in HRQoL between disease states and to compare the HRQoL of IBD patients with that of the general population.

Methods

The study population comprised 2,931 IBD patients over 18 picked from a national Social Insurance Institute register and from a patient organization register. The 15D data for the general population came from the National Health 2000 Health Examination Survey.

Results

For patients with IBD, the 15D tool was feasible and had good discriminatory power. The total 15D score was significantly higher among patients with less active disease estimated by frequency of IBD symptoms and was strongly correlated with total IBDQ score. The general population scored significantly higher than did the study subjects on most of the 15D dimensions.

Conclusions

The 15D was a fast and easy-to-apply method for the examination of HRQoL in IBD patients. In addition to HRQoL studies it could be used in everyday practice as well. Patients with IBD have worse HRQoL than do gender- and age-standardized controls.

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Literatur
1.
Zurück zum Zitat Fitzpatrick, R., Fletcher, A., Gore, S., et al. (1992). Quality of life measures in health care. I. Applications and issues in assessment. BMJ, 305, 1074–1077.CrossRefPubMed Fitzpatrick, R., Fletcher, A., Gore, S., et al. (1992). Quality of life measures in health care. I. Applications and issues in assessment. BMJ, 305, 1074–1077.CrossRefPubMed
2.
Zurück zum Zitat Irvine, E. J. (2008). Quality of life in patients with ulcerative colitis: Past, present, and future. Inflammatory Bowel Diseases, 14, 554–565.CrossRefPubMed Irvine, E. J. (2008). Quality of life in patients with ulcerative colitis: Past, present, and future. Inflammatory Bowel Diseases, 14, 554–565.CrossRefPubMed
3.
Zurück zum Zitat Holtmann, M. H., & Galle, P. R. (2004). Current concept of pathophysiological understanding and natural course of ulcerative colitis. Langenbeck’s Archives of Surgery, 389, 341–349.CrossRefPubMed Holtmann, M. H., & Galle, P. R. (2004). Current concept of pathophysiological understanding and natural course of ulcerative colitis. Langenbeck’s Archives of Surgery, 389, 341–349.CrossRefPubMed
4.
Zurück zum Zitat Stange, E. F., Travis, S. P., Vermeire, S., et al. (2006). European evidence based consensus on the diagnosis and management of Crohn’s disease: Definitions and diagnosis. Gut, 55, i1–i15.CrossRefPubMed Stange, E. F., Travis, S. P., Vermeire, S., et al. (2006). European evidence based consensus on the diagnosis and management of Crohn’s disease: Definitions and diagnosis. Gut, 55, i1–i15.CrossRefPubMed
5.
Zurück zum Zitat Guyatt, G., Mitchell, A., Irvine, E. J., et al. (1989). A new measure of health status for clinical trials in inflammatory bowel disease. Gastroenterology, 96, 804–810.PubMed Guyatt, G., Mitchell, A., Irvine, E. J., et al. (1989). A new measure of health status for clinical trials in inflammatory bowel disease. Gastroenterology, 96, 804–810.PubMed
6.
Zurück zum Zitat Bernklev, T., Jahnsen, J., Lygren, I., et al. (2005). Health-related quality of life in patients with inflammatory bowel disease measured with the Short Form-36: Psychometric assessments and a comparison with general population norms. Inflammatory Bowel Diseases, 11, 909–918.CrossRefPubMed Bernklev, T., Jahnsen, J., Lygren, I., et al. (2005). Health-related quality of life in patients with inflammatory bowel disease measured with the Short Form-36: Psychometric assessments and a comparison with general population norms. Inflammatory Bowel Diseases, 11, 909–918.CrossRefPubMed
7.
Zurück zum Zitat Casellas, F., Arenas, J. I., Baudet, J. S., et al. (2005). Impairment of health-related quality of life in patients with inflammatory bowel disease: A Spanish multicenter study. Inflammatory Bowel Diseases, 11, 488–496.CrossRefPubMed Casellas, F., Arenas, J. I., Baudet, J. S., et al. (2005). Impairment of health-related quality of life in patients with inflammatory bowel disease: A Spanish multicenter study. Inflammatory Bowel Diseases, 11, 488–496.CrossRefPubMed
8.
Zurück zum Zitat Irvine, E. J., Feagan, B., Rochon, J., et al. (1994). Quality of life: A valid and reliable measure of therapeutic efficacy in the treatment of inflammatory bowel disease. Gastroenterology, 106, 287–296.PubMed Irvine, E. J., Feagan, B., Rochon, J., et al. (1994). Quality of life: A valid and reliable measure of therapeutic efficacy in the treatment of inflammatory bowel disease. Gastroenterology, 106, 287–296.PubMed
9.
Zurück zum Zitat Drossman, D. A., Patrick, D. L., Mitchell, C. M., et al. (1989). Health-related quality of life in inflammatory bowel disease. Functional status and patient worries and concerns. Digestive Diseases and Sciences, 34, 1379–1386.CrossRefPubMed Drossman, D. A., Patrick, D. L., Mitchell, C. M., et al. (1989). Health-related quality of life in inflammatory bowel disease. Functional status and patient worries and concerns. Digestive Diseases and Sciences, 34, 1379–1386.CrossRefPubMed
10.
Zurück zum Zitat Graff, L. A., Walker, J. R., Lix, L., et al. (2006). The relationship of inflammatory bowel disease type and activity to psychological functioning and quality of life. Clinical Gastroenterology and Hepatology, 4, 1491–1501.CrossRefPubMed Graff, L. A., Walker, J. R., Lix, L., et al. (2006). The relationship of inflammatory bowel disease type and activity to psychological functioning and quality of life. Clinical Gastroenterology and Hepatology, 4, 1491–1501.CrossRefPubMed
11.
Zurück zum Zitat Irvine, E. J. (1996). Quality of life in inflammatory bowel disease and other chronic diseases. Scandinavian Journal of Gastroenterology, 31(Suppl), 26–28.CrossRef Irvine, E. J. (1996). Quality of life in inflammatory bowel disease and other chronic diseases. Scandinavian Journal of Gastroenterology, 31(Suppl), 26–28.CrossRef
12.
Zurück zum Zitat Guyatt, G. H., Feeny, D. H., & Patrick, D. L. (1993). Measuring health-related quality of life. Annals of Internal Medicine, 118, 622–629.PubMed Guyatt, G. H., Feeny, D. H., & Patrick, D. L. (1993). Measuring health-related quality of life. Annals of Internal Medicine, 118, 622–629.PubMed
13.
Zurück zum Zitat Aromaa, A., & Koskinen, S. (2004). Health and functional capacity in Finland. Baseline results of the Health 2000 health examination survey. Publications of National Public Health Institute, Series B 12/2004:171. Aromaa, A., & Koskinen, S. (2004). Health and functional capacity in Finland. Baseline results of the Health 2000 health examination survey. Publications of National Public Health Institute, Series B 12/2004:171.
15.
Zurück zum Zitat Sintonen, H. (2001). The 15D instrument of health-related quality of life: Properties and applications. Annals of Medicine, 33, 328–336.CrossRefPubMed Sintonen, H. (2001). The 15D instrument of health-related quality of life: Properties and applications. Annals of Medicine, 33, 328–336.CrossRefPubMed
16.
Zurück zum Zitat Hawthorne, G., Richardson, J., & Day, N. A. (2001). A comparison of the Assessment of Quality of Life (AQoL) with four other generic utility instruments. Annals of Medicine, 33, 358–370.CrossRefPubMed Hawthorne, G., Richardson, J., & Day, N. A. (2001). A comparison of the Assessment of Quality of Life (AQoL) with four other generic utility instruments. Annals of Medicine, 33, 358–370.CrossRefPubMed
17.
Zurück zum Zitat Saarni, S. I., Härkänen, T., Sintonen, H., et al. (2006). The impact of 29 chronic conditions on health-related quality of life: A general population survey in Finland using 15D and EQ-5D. Quality of Life Research, 15, 1403–1414.CrossRefPubMed Saarni, S. I., Härkänen, T., Sintonen, H., et al. (2006). The impact of 29 chronic conditions on health-related quality of life: A general population survey in Finland using 15D and EQ-5D. Quality of Life Research, 15, 1403–1414.CrossRefPubMed
18.
Zurück zum Zitat Pallis, A. G., Mouzas, I. A., & Vlachonikolis, I. G. (2004). The inflammatory bowel disease questionnaire: A review of its national validation studies. Inflammatory Bowel Disease, 10, 261–269.CrossRef Pallis, A. G., Mouzas, I. A., & Vlachonikolis, I. G. (2004). The inflammatory bowel disease questionnaire: A review of its national validation studies. Inflammatory Bowel Disease, 10, 261–269.CrossRef
19.
Zurück zum Zitat Stjernman, H., Granno, C., Bodemar, G., et al. (2006). Evaluation of the inflammatory bowel disease questionnaire in Swedish patients with Crohn’s disease. Scandinavian Journal of Gastroenterology, 41, 934–943.CrossRefPubMed Stjernman, H., Granno, C., Bodemar, G., et al. (2006). Evaluation of the inflammatory bowel disease questionnaire in Swedish patients with Crohn’s disease. Scandinavian Journal of Gastroenterology, 41, 934–943.CrossRefPubMed
20.
Zurück zum Zitat Ren, W. H., Lai, M., & Chen, Y. (2007). Validation of the mainland Chinese version of the Inflammatory Bowel Disease Questionnaire (IBDQ) for ulcerative colitis and Crohn’s disease. Inflammatory Bowel Disease, 13, 903–910.CrossRef Ren, W. H., Lai, M., & Chen, Y. (2007). Validation of the mainland Chinese version of the Inflammatory Bowel Disease Questionnaire (IBDQ) for ulcerative colitis and Crohn’s disease. Inflammatory Bowel Disease, 13, 903–910.CrossRef
21.
Zurück zum Zitat Borgaonkar, M. R., & Irvine, E. J. (2000). Quality of life measurement in gastrointestinal and liver diseases. Gut, 47, 444–454.CrossRefPubMed Borgaonkar, M. R., & Irvine, E. J. (2000). Quality of life measurement in gastrointestinal and liver diseases. Gut, 47, 444–454.CrossRefPubMed
22.
Zurück zum Zitat Ghosh, S., & Mitchell, R. (2007). Impact of inflammatory bowel disease on quality of life: results of the European Federation of Crohn’s and Ulcerative Colitis Associations (EFCCA) patient survey. Journal of Crohn’s and Colitis, 1, 10–20.CrossRef Ghosh, S., & Mitchell, R. (2007). Impact of inflammatory bowel disease on quality of life: results of the European Federation of Crohn’s and Ulcerative Colitis Associations (EFCCA) patient survey. Journal of Crohn’s and Colitis, 1, 10–20.CrossRef
23.
Zurück zum Zitat Haapamäki, J., Turunen, U., Roine, R. P., et al. (2008). Finnish patients with inflammatory bowel disease have fewer symptoms and are more satisfied with their treatment than patients in the previous European survey. Scandinavian Journal of Gastroenterology, 43, 821–830.CrossRefPubMed Haapamäki, J., Turunen, U., Roine, R. P., et al. (2008). Finnish patients with inflammatory bowel disease have fewer symptoms and are more satisfied with their treatment than patients in the previous European survey. Scandinavian Journal of Gastroenterology, 43, 821–830.CrossRefPubMed
24.
Zurück zum Zitat Marquis, P., Marrel, A., & Jambon, B. (2003). Quality of life in patients with stomas: the Montreux Study. Ostomy/Wound Management, 49, 48–55.PubMed Marquis, P., Marrel, A., & Jambon, B. (2003). Quality of life in patients with stomas: the Montreux Study. Ostomy/Wound Management, 49, 48–55.PubMed
25.
Zurück zum Zitat Krouse, R., Grant, M., Ferrell, B., et al. (2007). Quality of life outcomes in 599 cancer and non-cancer patients with colostomies. The Journal of Surgical Research, 138(1), 79–87.CrossRefPubMed Krouse, R., Grant, M., Ferrell, B., et al. (2007). Quality of life outcomes in 599 cancer and non-cancer patients with colostomies. The Journal of Surgical Research, 138(1), 79–87.CrossRefPubMed
26.
Zurück zum Zitat Camilleri-Brennan, J., & Steele, R. J. C. (2001). Objective assessment of quality of life following panproctocolectomy and ileostomy for ulcerative colitis. Annals of the Royal College of Surgeons of England, 83, 321–324.PubMed Camilleri-Brennan, J., & Steele, R. J. C. (2001). Objective assessment of quality of life following panproctocolectomy and ileostomy for ulcerative colitis. Annals of the Royal College of Surgeons of England, 83, 321–324.PubMed
27.
Zurück zum Zitat Nordin, K., Påhlman, L., Larsson, K., et al. (2002). Health-related quality of life and psychological distress in a population-based sample of Swedish patients with inflammatory bowel disease. Scandinavian Journal of Gastroenterology, 37, 450–457.CrossRefPubMed Nordin, K., Påhlman, L., Larsson, K., et al. (2002). Health-related quality of life and psychological distress in a population-based sample of Swedish patients with inflammatory bowel disease. Scandinavian Journal of Gastroenterology, 37, 450–457.CrossRefPubMed
28.
Zurück zum Zitat Lix, L. M., Graff, L. A., Walker, J. R., et al. (2008). Longitudinal study of quality of life and psychological functioning for active, fluctuating, and inactive disease patterns in inflammatory bowel disease. Inflammatory Bowel Disease, 14, 1575–1584.CrossRef Lix, L. M., Graff, L. A., Walker, J. R., et al. (2008). Longitudinal study of quality of life and psychological functioning for active, fluctuating, and inactive disease patterns in inflammatory bowel disease. Inflammatory Bowel Disease, 14, 1575–1584.CrossRef
29.
Zurück zum Zitat Irvine, E. J. (2004). Review article: patients’ fears and unmet needs in inflammatory bowel disease. Alimentary Pharmacology & Therapeutics, 20(Suppl. 4), 54–59.CrossRef Irvine, E. J. (2004). Review article: patients’ fears and unmet needs in inflammatory bowel disease. Alimentary Pharmacology & Therapeutics, 20(Suppl. 4), 54–59.CrossRef
Metadaten
Titel
Health-related quality of life in inflammatory bowel disease measured with the generic 15D instrument
verfasst von
Johanna Haapamäki
Risto P. Roine
Harri Sintonen
Ulla Turunen
Martti A. Färkkilä
Perttu E. T. Arkkila
Publikationsdatum
01.08.2010
Verlag
Springer Netherlands
Erschienen in
Quality of Life Research / Ausgabe 6/2010
Print ISSN: 0962-9343
Elektronische ISSN: 1573-2649
DOI
https://doi.org/10.1007/s11136-010-9650-4

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