nach oben

Erschienen in:

2017 | OriginalPaper | Buchkapitel

5. Hemoglobin-Based Molecular Assembly

verfasst von : Li Duan, Yi Jia, Junbai Li

Erschienen in: Supramolecular Chemistry of Biomimetic Systems

Verlag: Springer Singapore

Einloggen

Aktivieren Sie unsere intelligente Suche, um passende Fachinhalte oder Patente zu finden.

search-config

KI-gestützte Suche

Aus

Abstract

Development of protein-based molecular devices is an active area of research due to their broad applications in biotechnology, biorelated chemistry, bioelectronics, and biomedical engineering. Hemoglobin (Hb) is a physiologically important oxygen-transport metalloprotein present in the red blood cells. In this chapter, we present the recent development in fabrication and tailoring of a variety of hemoglobin protein shells via covalent layer-by-layer (LbL) assembly combined with template technique. Also, the developed strategy is effective and flexible, advantageous for avoiding denaturation of proteins. The as-fabricated Hb shells have better applications in drug delivery and controlled release, biosensors, biocatalysis, and bioreactors due to the enhancement of biological availability. In view of the carrying-oxygen function of Hb protein in blood, we particularly focus on the potential applications of hemoglobin-based nanoarchitectonic assemblies as artificial blood substitutes. These novel oxygen carriers exhibit advantages over traditional carriers and will greatly promote research on reliable and feasible artificial blood substitutes.

Sie haben noch keine Lizenz? Dann Informieren Sie sich jetzt über unsere Produkte:

Springer Professional "Wirtschaft+Technik"

Online-Abonnement

Mit Springer Professional "Wirtschaft+Technik" erhalten Sie Zugriff auf:

über 102.000 Bücher
über 537 Zeitschriften

aus folgenden Fachgebieten:

Automobil + Motoren
Bauwesen + Immobilien
Business IT + Informatik
Elektrotechnik + Elektronik
Energie + Nachhaltigkeit
Finance + Banking
Management + Führung
Marketing + Vertrieb
Maschinenbau + Werkstoffe
Versicherung + Risiko

Jetzt Wissensvorsprung sichern!

Jetzt informieren

Springer Professional "Technik"

Online-Abonnement

Mit Springer Professional "Technik" erhalten Sie Zugriff auf:

über 67.000 Bücher
über 390 Zeitschriften

aus folgenden Fachgebieten:

Automobil + Motoren
Bauwesen + Immobilien
Business IT + Informatik
Elektrotechnik + Elektronik
Energie + Nachhaltigkeit
Maschinenbau + Werkstoffe

Jetzt Wissensvorsprung sichern!

Jetzt informieren

Vorheriges Kapitel Polysaccharides-Based Microcapsules

Nächstes Kapitel Photosystem II Based Multilayers

He Q, Cui Y, Li JB (2009) Molecular assembly and application of biomimetic microcapsules. Chem Soc Rev 38:2292–2303CrossRef

Bao G, Suresh S (2003) Cell and molecular mechanics of biological materials. Nat Mater 2:715–721CrossRef

Wendell DW, Patti J, Montemagno CD (2006) Using biological inspiration to engineer functional nanostructured materials. Small 2:1324–1329CrossRef

Lowe CR (2000) Nanobiotechnology: the fabrication and applications of chemical and biological nanostructures. Curr Opin Struct Biol 10:428–432CrossRef

Biagioli M, Pinto M, Cesselli D et al (2009) Unexpected expression of α- and β-globin in mesencephalic dopaminergic neurons and glial cells. Proc Natl Acad Sci USA 106:15454–15459CrossRef

Linberg R, Conover CD, Shum KL et al (1998) Hemoglobin based oxygen carriers: how much methemoglobin is too much? Artif Cells Blood Substit Immobil Biotechnol 26:133–148CrossRef

Guyton AC (2005) Medical physiology, 11th edn, p 509

Shutava TG, Kommireddy DS, Lvov YM (2006) Polyelectrolyte/enzyme multilayer as functionalprotective nano/barrier in oxidizing media. J Am Chem Soc 128:9926–9934CrossRef

Uto K, Yamamoto K, Kishimoto N et al (2008) J Mater Chem 18:3876–3884CrossRef

10.

Hwang I, Baek K, Jung M et al (2007) Noncovalent immobilization of proteins on a solid surface by cucurbit[7]uril-ferrocenemethylammonium pair, a potential replacement of Biotin−Avidin Pair. J Am Chem Soc 129:4170–4171CrossRef

11.

Wang Q, Yang Z, Gao Y et al (2008) Enzymatic hydrogelation to immobilize an enzyme for high activity and stability. Soft Matter 4:550–553CrossRef

12.

Onda M, Lvov Y, Ariga K et al (1996) Sequential reactions by glucose oxidase/peroxidase molecular films assembled by layer-by-layer alternate adsorption. Biotechnol Bioeng 51:163–167CrossRef

13.

Decher G (1997) Fuzzy nanoassemblies: toward layered polymeric multicomposites. Science 277:1232–1237CrossRef

14.

Johnston APR, Cortez C, Angelatos AS et al (2006) Layer-by-layer engineered capsules and their applications. Curr Opin Colloid Interface Sci 11:203–209CrossRef

15.

Wang KW, He Q, Cui Y et al (2007) Photosensitive drugs encapsulizated by biodegradable microcapsules applied for photodynamic Therapy. J Mater Chem 17:4018–4021CrossRef

16.

Mercato LLD, Rivera-Gil P, Abbasi AZ et al (2010) LbL multilayer capsules: recent progress and future outlook for their use in life sciences. Nanoscale 2:458–467CrossRef

17.

Tang Z, Wang Y, Podsiadlo P et al (2007) Biomedical application of layer-by-layer assembly: from biomimetics to tissue engineering. Adv Mater 19:906–928CrossRef

18.

De Geest BG, Sanders NN, Sukhorukov GB et al (2007) Release mechanisms for polyelectrolyte capsules. Chem Soc Rev 36:636–649CrossRef

19.

Qi W, Wang AH, Yang Y et al (2010) The lectin binding and targetable cellular uptake of lipid-coated polysaccharide microcapsules. J Mater Chem 20:2121–2127CrossRef

20.

Caruso F, Trau D, Möhwald H et al (2000) Enzyme encapsulation in layer-by-layer engineered polymer multilayer capsules. Langmuir 16:1485–1488CrossRef

21.

Tong WJ, Gao CY, Möhwald H (2006) Single polyelectrolyte microcapsules fabricated by glutaraldehyde-mediated covalent Layer-by-Layer assembly. Macromol Rapid Commun 27:2078–2083CrossRef

22.

Skirtach AG, Déjugnat C, Braun D et al (2005) The role of metal nanoparticles in remote release of encapsulated materials. Nano Lett 5:1371–1377CrossRef

23.

Qi W, Duan L, Li JB (2011) Fabrication of glucose-sensitive protein microcapsules and their applications. Soft Matter 7:1571–1576CrossRef

24.

Duan L, He Q, Yan XH et al (2007) Hemoglobin protein hollow shells fabricated through covalent Layer-by-Layer assembly. Biochem Biophys Res Commun 354:357–362CrossRef

25.

Qi W, Duan L, Wang KW et al (2008) Motor protein CF₀F₁ reconstituted in lipid-Coated hemoglobin microcapsules for ATP synthesis. Adv Mater 20:601–605CrossRef

26.

Duan L, Qi W, Yan XH et al (2009) Proton gradients produced by glucose oxidase microcapsules containing motor F₀F₁-ATPase for continuous ATP biosynthesis. J Phys Chem B 113:395–399CrossRef

27.

He Q, Tian Y, Möhwald H et al (2009) Biointerfacing luminescent nanotubes. Soft Matter 5:300–303CrossRef

28.

Shan E, Han HX, Cosnier S (2007) Self-assembled films of hemoglobin/laponite/chitosan: application for the direct electrochemistry and catalysis to hydrogen peroxide. Biomacromol 8:3041–3046CrossRef

29.

Qi W, Duan L, Yan XH et al (2009) Glucose-sensitive microcapsules from glutaraldehyde cross-linked hemoglobin and glucose oxidase. Biomacromol 10:1212–1216CrossRef

30.

Qi W, Yan XH, Fei JB et al (2009) Triggered release of insulin from glucose-sensitive enzyme multilayer shells. Biomaterials 30:2799–2806CrossRef

31.

Choi HJ, Montemagno CD (2005) Artificial organelle: ATP synthesis from cellular mimetic polymersomes. Nano Lett 5:2538–2542CrossRef

32.

Capaldi RA, Aggeler R (2002) Mechanism of the F₀F₁-ATP synthase, a biological rotary motor. Trends Biochem Sci 27:154–160CrossRef

33.

Fischer S, Etzold C, Turina P et al (1994) ATP synthesis catalyzed by the ATP synthase of Escherichia coli reconstituted into liposomes. Eur J Biochem 225:167–172CrossRef

34.

Steinberg-Yfrach G, Rigaud JL, Durantini EN et al (1998) Light-driven production of ATP catalyzed by F₀F₁-ATP synthase in an artificial photosynthetic membrane. Nature 392:479–482CrossRef

35.

Luo TJM, Soong R, Lan E et al (2005) Photo-induced proton gradients and ATP biosynthesis produced by vesicles encapsulated in a silica matrix. Nat Mater 4:220–224CrossRef

36.

Duan L, He Q, Wang KW et al (2007) Adenosine triphosphate biosynthesis catalyzed by F_oF₁ ATP synthase assembled in polymer microcapsules. Angew Chem Int Ed 46:6996–7000CrossRef

37.

Richard P, Rigaud JL, Gräber P (1990) Reconstitution of CF₀F₁ into liposomes using a new reconstitution procedure. Eur J Biochem 193:921–925CrossRef

38.

Buehler PW, D’Agnillo F, Schaer DJ (2010) Hemoglobin-based oxygen carriers: from mechanisms of toxicity and clearance to rational drug design. Trends Mol Med 16:447–457CrossRef

39.

Liu LM, Zeng M, Stamler JS (1999) Hemoglobin induction in mouse macrophages. Proc Natl Acad Sci USA 96:6643–6647CrossRef

40.

Widmer CC, Pereira CP, Gehrig P et al (2010) Hemoglobin can attenuate hydrogen peroxide-induced oxidative stress by acting as an antioxidative peroxidase. Antioxid Redox Signal 12:185–198CrossRef

41.

Kameta N, Minamikawa H, Masuda M (2011) Supramolecular organic nanotubes: how to utilize the inner nanospace and the outer space. Soft Matter 7:4539–4561CrossRef

42.

Komatsu T, Qu X, Ihara H et al (2011) Virus trap in human serum albumin nanotube. J Am Chem Soc 133:3246–3248CrossRef

43.

Geng Y, Dalhaimer P, Cai S et al (2007) Shape effects of filaments versus spherical particles in flow and drug delivery. Nat Nanotechnol 2:249–255CrossRef

44.

Chen B, Jia Y, Zhao J et al (2013) Assembled hemoglobin and catalase nanotubes for the treatment of oxidative stress. J Phys Chem C 117:19751–19758

45.

Pape A (2007) Alternatives to allogeneic blood transfusions. Best Pract Res Clin Anaesthesiol 21:221–239CrossRef

46.

Ness PM, Cushing MM (2007) Oxygen therapeutics pursuit of an alternative to the donor red blood cell. Arch Pathol Lab Med 131:734–741

47.

Modery-Pawlowski CL, Tian LL, Pan V et al (2013) Synthetic approaches to RBC mimicry and oxygen carrier systems. Biomacromol 14:939–948CrossRef

48.

Chang TMS (2004) Hemoglobin-based red blood cell substitutes. Artif Organs 28:789–794CrossRef

49.

Alayash AI (2014) Blood substitutes why haven’t we been more successful. Trends Biotechnol 32:177–186CrossRef

50.

Jia Y, Duan L, Li JB (2016) Hemoglobin-based nanoarchitectonic assemblies as oxygen carriers. Adv Mater 28:1312–1318CrossRef

51.

Nadithe V, Bae YH (2010) Synthesis and characterization of hemoglobin conjugates with antioxidant enzymes via poly(ethylene glycol) cross-linker (Hb-SOD-CAT) for protection from free radical stress. Int J Biol Macromol 47:603–613CrossRef

52.

Hathazi D, Mott AC, Vaida A et al (2014) Oxidative protection of hemoglobin and hemerythrin by cross-linking with a nonheme iron peroxidase: potentially improved oxygen carriers for use in blood substitutes. Biomacromol 15:1920–1927CrossRef

53.

Simoni J, Simoni G, Wesson DE et al (2012) ATP-adenosine-glutathione cross-linked hemoglobin as clinically useful oxygen carrier. Curr Drug Discov Technol 9:173–187CrossRef

54.

Chang TMS (2010) Blood replacement with nanobiotechnologically engineered hemoglobin and hemoglobin nanocapsules. Wiley Interdiscip Rev Nanomed Nanobiotechnol 2:418–430CrossRef

55.

Rameez S, Alosta H, Palmer AF (2008) Biocompatible and biodegradable polymersome encapsulated hemoglobin: a potential oxygen carrier. Bioconjugate Chem 19:1025–1032CrossRef

56.

Ariga K, Yamauchi Y, Rydzek G et al (2014) Layer-by-layer nanoarchitectonics: invention innovation and evolution. Chem Lett 43:36–68CrossRef

57.

Duan L, Yan XH, Wang AH et al (2012) Highly loaded hemoglobin spheres as promising artificial oxygen carriers. ACS Nano 6:6897–6904CrossRef

58.

Jia Y, Cui Y, Fei JB et al (2012) Construction and evaluation of hemoglobin-based capsules as blood substitutes. Adv Funct Mater 22:1446–1453CrossRef

59.

Duan L, Du LL, Jia Y et al (2015) High impact of uranyl ions on carrying-releasing oxygen capability of hemoglobin-based blood substitutes. Chem Eur J 21:520–525CrossRef

60.

Jia Y, Li JB (2015) Molecular assembly of schiff base interactions: construction and application. Chem Rev 115:1597–1621CrossRef

61.

Squires JE (2002) Artificial blood. Science 295:1002–1005CrossRef

62.

Chang TMS, D’Agnillo F, Yu WP et al (2000) Two future generations of blood substitutes based on polyhemoglobin–SOD–catalase and nanoencapsulation. Adv Drug Deliv Rev 40:213–218CrossRef

63.

Dusseault J, Leblond FA, Robitaille R et al (2005) Microencapsulation of living cells in semi-permeable membranes with covalently cross-linked layers. Biomaterials 26:1515–1522CrossRef

64.

Zhao J, Liu CS, Yuan Y et al (2007) Preparation of hemoglobin-loaded nano-sized particles with porous structure as oxygen carriers. Biomaterials 28:1414–1422CrossRef

65.

Sun J, Huang YB, Shi Q et al (2009) Oxygen carrier based on hemoglobin/poly(L-lysine)-block-poly(L-phenylalanine) vesicles. Langmuir 25:13726–13729CrossRef

66.

Komatsu T, Matsukawa Y, Tsuchida E (2001) Reaction of nitric oxide with synthetic hemoprotein, human serum albumin incorporating tetraphenylporphinatoiron(II) derivatives. Bioconjugate Chem 12:71–75CrossRef

67.

Yang Y, Jia Y, Gao L et al (2011) Fabrication of autofluorescent protein coated mesoporous silica nanoparticles for biological application. Chem Commun 47:12167–12169CrossRef

68.

Monier M, Ayad DM, Wei Y et al (2010) Adsorption of Cu(II), Co(II), and Ni(II) ions by modified magnetic chitosan chelating resin. J Hazard Mater 77:962–970CrossRef

Titel: Hemoglobin-Based Molecular Assembly
verfasst von: Li Duan
Yi Jia
Junbai Li
Verlag: Springer Singapore
Buch: Supramolecular Chemistry of Biomimetic Systems
Print ISBN: 978-981-10-6058-8

Electronic ISBN: 978-981-10-6059-5

Copyright-Jahr: 2017
DOI: https://doi.org/10.1007/978-981-10-6059-5_5

Premium Partner

Marktübersichten

Die im Laufe eines Jahres in der „adhäsion“ veröffentlichten Marktübersichten helfen Anwendern verschiedenster Branchen, sich einen gezielten Überblick über Lieferantenangebote zu verschaffen.

Zur Marktübersicht