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2015 | OriginalPaper | Buchkapitel

14. Immuno-Epidemiological Modeling

verfasst von : Maia Martcheva

Erschienen in: An Introduction to Mathematical Epidemiology

Verlag: Springer US

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Abstract

This chapter introduces and studies multiscale nested immuno-epidemiological models. The chapter begins with brief introduction to within-host dynamics and within-host modeling. Then the chapter introduces nested immuno-epidemiological models. The first model studied is a nested SI model of HIV. Using data, the chapter argues that the transmission rate is not a linear function of the viral load. The epidemiological reproduction number and prevalence of HIV are derived and studied in terms of the within-host viral load. In addition, a nested immuno-epidemiological model with immune response in the within-host model is introduced and studied.

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Metadaten
Titel
Immuno-Epidemiological Modeling
verfasst von
Maia Martcheva
Copyright-Jahr
2015
Verlag
Springer US
DOI
https://doi.org/10.1007/978-1-4899-7612-3_14

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