In Vitro Modeling for Bioelectrical Impedance Measurement in Compartmental Syndrome

Bioimpedance measurement was performed in vitro on a compartment model as part of the investigation for a non invasive procedure in diagnosing a compartmental syndrome (CS). A model was constructed to mimic the body compartment of a lower leg. The cellular fluid of potassium ion (K

+

) of different concentration was prepared in vitro. The model was filled with K

+

solution and protein substances. Prior to the impedance measurement; pressure was applied within the compartment. This setup was to demonstrate physiologic events during CS. The impedance of the compartment at various concentration of K

+

, protein and pressure were measured with a commercial tetra polar bioimpendance analyzer. The results obtained from this investigation had shown positive correlation as predicted.