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2016 | OriginalPaper | Buchkapitel

Inference of Gene Regulatory Network Based on Radial Basis Function Neural Network

verfasst von : Sanrong Liu, Bin Yang, Haifeng Wang

Erschienen in: Machine Learning, Optimization, and Big Data

Verlag: Springer International Publishing

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Abstract

Inference of gene regulatory network (GRN) from gene expression data is still a challenging work. The supervised approaches perform better than unsupervised approaches. In this paper, we develop a new supervised approach based on radial basis function (RBF) neural network for inference of gene regulatory network. A new hybrid evolutionary method based on dissipative particle swarm optimization (DPSO) and firefly algorithm (FA) is proposed to optimize the parameters of RBF. The data from E.coli network is used to test our method and results reveal that our method performs than classical approaches.

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Metadaten
Titel
Inference of Gene Regulatory Network Based on Radial Basis Function Neural Network
verfasst von
Sanrong Liu
Bin Yang
Haifeng Wang
Copyright-Jahr
2016
DOI
https://doi.org/10.1007/978-3-319-51469-7_39

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