Inhibition of Autoxidation by Vitamin E and Bilirubin

Antioxidants are known to have an anticarcinogenic effect1,2. Although they are capable of reducing the incidence of tumors induced by chemical carcinogens, their effect on radiation-induced tumors has not been clearly demonstrated3,4. The mechanism of the anticarcinogenic action of antioxidants is poorly understood, and despite numerous mechanistic studies of autoxidation processes and antioxidants in model systems, detailed reaction mechanisms under physiological conditions are still elusive. However, inhibition of free radical processes may be an important part of this activity.