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Erschienen in:
The Cell–Surface Interaction Kapitel lesen Erstes Kapitel lesen

2012 | OriginalPaper | Buchkapitel

Interaction of Cartilage and Ceramic Matrix

verfasst von : K. Wiegandt, C. Goepfert, R. Pörtner, R. Janssen

Erschienen in: Tissue Engineering III: Cell - Surface Interactions for Tissue Culture

Verlag: Springer Berlin Heidelberg

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Abstract

As subchondral bone is often affected during cartilage injuries, the aim of research is to generate osteochondral implants in vitro using tissue engineering techniques. These constructs consist of a cartilage layer grown on top of a bone phase. In clinical applications, phosphate ceramics have gained acceptance as bone substitute materials because of their great affinity to natural bone. Furthermore, the interaction between cartilage and the underlying bone equivalent is essential for the development and success of osteochondral implants. Here, the influence of a carrier containing hydroxyapatite on the quality of cartilage constructs generated in vitro is investigated. Attempts are made to explain the effects described, by considering chemical and physical properties of the biomaterial.

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Vorheriges Kapitel Designing the Biocompatibility of Biohybrids
Nächstes Kapitel Bioresorption and Degradation of Biomaterials
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Metadaten
Titel
Interaction of Cartilage and Ceramic Matrix
verfasst von
K. Wiegandt
C. Goepfert
R. Pörtner
R. Janssen
Copyright-Jahr
2012
Verlag
Springer Berlin Heidelberg
Buch
Tissue Engineering III: Cell - Surface Interactions for Tissue Culture

Print ISBN: 978-3-642-28281-2

Electronic ISBN: 978-3-642-28282-9

Copyright-Jahr: 2012

DOI
https://doi.org/10.1007/10_2011_105

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