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2020 | OriginalPaper | Buchkapitel

Environmental Water Pollution, Endocrine Interference and Ecotoxicity of 4-tert-Octylphenol: A Review

verfasst von : Lamidi W. B. Olaniyan, Omobola O. Okoh, Noxolo T. Mkwetshana, Anthony I. Okoh

Erschienen in: Reviews of Environmental Contamination and Toxicology Volume 248

Verlag: Springer International Publishing

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Abstract

4-tert-Octylphenol is a degradation product of non-ionic surfactants alkylphenol polyethoxylates as well as raw material for a number of industrial applications. It is a multimedia compound having been detected in all environmental compartments such as indoor air and surface waters. The pollutant is biodegradable, but certain degradation products are more toxic than the parent compound. Newer removal techniques from environmental waters have been presented, but they still require development for large-scale applications. Wastewater treatment by plant enzymes such as peroxidases offers promise in total removal of 4-tert-octylphenol leaving less toxic degradation products. The pollutant’s endocrine interference has been well reported but more in oestrogens than in any other signalling pathways through which it is believed to exert toxicity on human and wildlife. In this paper we carried out a review of the activities of this pollutant in environmental waters, endocrine interference and relevance to its toxicities and concluded that inadequate knowledge of its endocrine activities impedes understanding of its toxicity which may frustrate current efforts at ridding the compound from the environment.

Graphical Abstract

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Zurück zum Zitat Hughes PJ, McLellan H, Lowes DA, Kahn SZ, Bilmen JG, Tovey SC, Godfrey RE, Michell RH, Kirk CJ, Michelangeli F (2000) Estrogenic alkylphenols induce cell death by inhibiting testis endoplasmic reticulum Ca2+ pumps. Biochem Biophys Res Commun 277(3):568–574 Hughes PJ, McLellan H, Lowes DA, Kahn SZ, Bilmen JG, Tovey SC, Godfrey RE, Michell RH, Kirk CJ, Michelangeli F (2000) Estrogenic alkylphenols induce cell death by inhibiting testis endoplasmic reticulum Ca2+ pumps. Biochem Biophys Res Commun 277(3):568–574
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Zurück zum Zitat Hwang KA, Kang NH, Yi BR, Lee HR, Park MA, Choi KC (2012) Genistein, a soy phytoestrogen, prevents the growth of BG-1 ovarian cancer cells induced by 17beta-estradiol or bisphenol A via the inhibition of cell cycle progression. Int J Oncol 42:733–740 Hwang KA, Kang NH, Yi BR, Lee HR, Park MA, Choi KC (2012) Genistein, a soy phytoestrogen, prevents the growth of BG-1 ovarian cancer cells induced by 17beta-estradiol or bisphenol A via the inhibition of cell cycle progression. Int J Oncol 42:733–740
Zurück zum Zitat Jambor T, Tvrdá E, Bistáková J, Forgács Z, Lukáč N (2016) The potential impact of 4-octylphenol on the basal and stimulated testosterone formation by isolated mice Leydig cells. J Cent Eur Agric 17(4):1274–1286 Jambor T, Tvrdá E, Bistáková J, Forgács Z, Lukáč N (2016) The potential impact of 4-octylphenol on the basal and stimulated testosterone formation by isolated mice Leydig cells. J Cent Eur Agric 17(4):1274–1286
Zurück zum Zitat Janicki T, Krupinski M, Długonsk J (2016) Degradation and toxicity reduction of the endocrine disruptors nonylphenol, 4-tert-octylphenol and 4-cumylphenol by the nonligninolytic fungus Umbelopsis isabellina. Bioresour Technol 200:223–229 Janicki T, Krupinski M, Długonsk J (2016) Degradation and toxicity reduction of the endocrine disruptors nonylphenol, 4-tert-octylphenol and 4-cumylphenol by the nonligninolytic fungus Umbelopsis isabellina. Bioresour Technol 200:223–229
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Zurück zum Zitat Kennedy RH, Pelletier JH, Tupper EJ, Hutchinson LM, Gosse JA (2012) Estrogen mimetic 4-tert-octylphenol enhances Ige-mediated degranulation of Rbl-2H3 mast cells. J Toxic Environ Health A 75(24):1451–1455 Kennedy RH, Pelletier JH, Tupper EJ, Hutchinson LM, Gosse JA (2012) Estrogen mimetic 4-tert-octylphenol enhances Ige-mediated degranulation of Rbl-2H3 mast cells. J Toxic Environ Health A 75(24):1451–1455
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Zurück zum Zitat Liu D, Wu S, Xu H, Zhang Q, Zhang S, Shi L, Yao C, Liu Y, Cheng J (2017) Distribution and bioaccumulation of endocrine disrupting chemicals in water, sediment and fishes in a shallow 36 Chinese freshwater lake: implications for ecological and human health risks. Ecotoxicol Environ Saf 140:222–229 Liu D, Wu S, Xu H, Zhang Q, Zhang S, Shi L, Yao C, Liu Y, Cheng J (2017) Distribution and bioaccumulation of endocrine disrupting chemicals in water, sediment and fishes in a shallow 36 Chinese freshwater lake: implications for ecological and human health risks. Ecotoxicol Environ Saf 140:222–229
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Zurück zum Zitat Park MA, Hwang KA, Lee HR, Yi BR, Choi KC (2011) Cell growth of BG-1 ovarian cancer cells was promoted by 4-tert-octylphenol and 4-nonylphenol via downregulation of TGF-β Receptor 2 and upregulation of c-myc. Toxicol Res 27(4):253–259 Park MA, Hwang KA, Lee HR, Yi BR, Choi KC (2011) Cell growth of BG-1 ovarian cancer cells was promoted by 4-tert-octylphenol and 4-nonylphenol via downregulation of TGF-β Receptor 2 and upregulation of c-myc. Toxicol Res 27(4):253–259
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Metadaten
Titel
Environmental Water Pollution, Endocrine Interference and Ecotoxicity of 4-tert-Octylphenol: A Review
verfasst von
Lamidi W. B. Olaniyan
Omobola O. Okoh
Noxolo T. Mkwetshana
Anthony I. Okoh
Copyright-Jahr
2020
DOI
https://doi.org/10.1007/398_2018_20