2011 | OriginalPaper | Buchkapitel
Sparse Multi-Shell Diffusion Imaging
verfasst von : Yogesh Rathi, O. Michailovich, K. Setsompop, S. Bouix, M. E. Shenton, C. -F. Westin
Erschienen in: Medical Image Computing and Computer-Assisted Intervention – MICCAI 2011
Verlag: Springer Berlin Heidelberg
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Diffusion magnetic resonance imaging (dMRI) is an important tool that allows non-invasive investigation of neural architecture of the brain. The data obtained from these
in-vivo
scans provides important information about the integrity and connectivity of neural fiber bundles in the brain. A multi-shell imaging (MSI) scan can be of great value in the study of several psychiatric and neurological disorders, yet its usability has been limited due to the long acquisition times required. A typical MSI scan involves acquiring a large number of gradient directions for the 2 (or more) spherical shells (several b-values), making the acquisition time significantly long for clinical application. In this work, we propose to use results from the theory of compressive sampling and determine the minimum number of gradient directions required to attain signal reconstruction similar to a traditional MSI scan. In particular, we propose a generalization of the single shell
spherical ridgelets
basis for sparse representation of multi shell signals. We demonstrate its efficacy on several synthetic and
in-vivo
data sets and perform quantitative comparisons with solid spherical harmonics based representation. Our preliminary results show that around 20-24 directions per shell are enough for robustly recovering the diffusion propagator.