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01.08.2015 | Original Paper

Synthesis, characterization, and micellar behaviors of hydroxyethyl cellulose-graft-poly(lactide/ε-caprolactone/p-dioxanone)

verfasst von: Wenjiao Ge, Yanzhu Guo, Haoquan Zhong, Xiaohui Wang, Runcang Sun

Erschienen in: Cellulose | Ausgabe 4/2015

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Abstract

In response to the shortage of petroleum resources and the growing need for sustainable development, cellulose-based amphiphilic copolymers have emerged as a new generation of value-added functional nanostructures from biomass resources. In this article, 17 amphiphilic hydroxyethyl cellulose-based graft copolymers with different side chains, including poly(lactide), poly(ε-caprolactone) and poly(p-dioxanone), were synthesized via homogeneous ring opening polymerization in ionic liquid 1-butyl-3-methylimidazolium chloride and characterized by FT-IR, ¹H NMR, thermogravimetric analysis and gel permeation chromatography. The resultant copolymers can self-assemble into micelles with a low critical micelle concentration that varies in the range of 0.03–0.24 mg/ml. TEM observations revealed the obtained micelles had a spherical and well-distributed morphology, and DLS analysis showed the nanoscaled sizes were between 40 and 150 nm. These HEC-based micelles can be used as nano-sized vesicles and have great latent forces in drug delivery systems.

Vorheriger Artikel Insight into miscibility behaviour of cellulose ester blends with N-vinyl pyrrolidone copolymers in terms of viscometric interaction parameters

Nächster Artikel Conferring antioxidant capacity to cellulose based materials by using enzymatically-modified products

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Titel: Synthesis, characterization, and micellar behaviors of hydroxyethyl cellulose-graft-poly(lactide/ε-caprolactone/p-dioxanone)
verfasst von: Wenjiao Ge
Yanzhu Guo
Haoquan Zhong
Xiaohui Wang
Runcang Sun
Publikationsdatum: 01.08.2015
Verlag: Springer Netherlands
Erschienen in: Cellulose / Ausgabe 4/2015
Print ISSN: 0969-0239
Elektronische ISSN: 1572-882X
DOI: https://doi.org/10.1007/s10570-015-0663-6

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