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Journal of Polymer Research

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01.02.2021 | ORIGINAL PAPER

Wound dressings based on chitosan and gelatin containing starch, sesame oil and banana peel powder for the treatment of skin burn wounds

verfasst von: Zhaleh Alborzi, Hossein Izadi-Vasafi, Faezeh Ghayoumi

Erschienen in: Journal of Polymer Research | Ausgabe 2/2021

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Abstract

A novel wound dressing based on chitosan (CS) and gelatin (GL) was prepared and the effect of potato-starch (ST), sesame oil (SO) and banana peel powder (BPP) on the physical and mechanical properties, cytocompatibility and wound healing capability of the films were evaluated. The mechanical results showed that the samples containing 5 wt% of potato-starch and 7 wt% of banana peel powder had the best mechanical properties (Elastic Modulus of 1930 MPa and Tensile Strength of 58.2 MPa). The scanning electron micrographs presented the uniform distribution of banana peel powder within the polymeric matrix up to 7 wt% of banana peel powder. By Adding banana peel powder to the film composition, the antibacterial activity of the films against E. coli and S. aureus bacteria increased. The MTT assay results revealed that the films containing banana peel powder had no toxicity and never caused cell death. In vivo experiments, using an animal model, demonstrated that the proliferation of blood vessels and angiogenesis along with connective tissues formations were accelerated considerably by the samples prepared in this study.

Vorheriger Artikel Pectin-based self-healing hydrogel with NaHCO3 degradability for drug loading and release

Nächster Artikel Dielectric and optical properties of alumina and silica nanoparticles dispersed poly(methyl methacrylate) matrix-based nanocomposites for advanced polymer technologies

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Titel: Wound dressings based on chitosan and gelatin containing starch, sesame oil and banana peel powder for the treatment of skin burn wounds
verfasst von: Zhaleh Alborzi
Hossein Izadi-Vasafi
Faezeh Ghayoumi
Publikationsdatum: 01.02.2021
Verlag: Springer Netherlands
Erschienen in: Journal of Polymer Research / Ausgabe 2/2021
Print ISSN: 1022-9760
Elektronische ISSN: 1572-8935
DOI: https://doi.org/10.1007/s10965-021-02427-y

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