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01.02.2010 | Brief Communication

Utility of the twelve-item World Health Organization Disability Assessment Schedule II (WHO-DAS II) for discriminating depression “caseness” and severity in Spanish primary care patients

verfasst von: Juan V. Luciano, José L. Ayuso-Mateos, Ana Fernandez, Jaume Aguado, Antoni Serrano-Blanco, Miquel Roca, Josep M. Haro

Erschienen in: Quality of Life Research | Ausgabe 1/2010

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Abstract

Purpose

The 12-item WHO-DAS II was developed to assess the activity limitations and participation restrictions experienced by individuals irrespective of medical diagnosis. In this paper we examine the known-groups’ validity of the instrument by evaluating its ability to discriminate between patients with/without major depression, patients with depression with/without medical comorbidity, and patients with depression with different depression severity.

Method

The participants were 3,615 PC patients from 17 regions of Spain, with a first-time diagnosis of major depressive episode according to the general practitioner. The 12-item WHO-DAS II, the PHQ-9, and a chronic medical conditions checklist were administered during the consultation.

Results

The statistical analyses indicated that the 12-item WHO-DAS II was able to discriminate between patients with/without depression and between those with different depression severity. The ROC analysis revealed that with a cutoff score ≥50, the instrument correctly classified 70.4% of the sample (area under the ROC curve = .76; sensitivity = 71.4%; specificity = 67.6%).

Conclusions

Overall, our results support the discriminant validity of the 12-item WHO-DAS II for major depression, being quite recommendable its use in epidemiological research.

Vorheriger Artikel The challenge of validating SF-12 for its use with community-dwelling elderly in Israel

Nächster Artikel The Functional Living Index-Cancer: estimating its reliability based on clinical trial data

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Titel: Utility of the twelve-item World Health Organization Disability Assessment Schedule II (WHO-DAS II) for discriminating depression “caseness” and severity in Spanish primary care patients
verfasst von: Juan V. Luciano
José L. Ayuso-Mateos
Ana Fernandez
Jaume Aguado
Antoni Serrano-Blanco
Miquel Roca
Josep M. Haro
Publikationsdatum: 01.02.2010
Verlag: Springer Netherlands
Erschienen in: Quality of Life Research / Ausgabe 1/2010
Print ISSN: 0962-9343
Elektronische ISSN: 1573-2649
DOI: https://doi.org/10.1007/s11136-009-9566-z

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Abstract

Purpose

Method

Results

Conclusions

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