Skip to main content
Erschienen in: Medical & Biological Engineering & Computing 5/2016

01.05.2016 | Original Article

Non-contact diagnostic system for sleep apnea–hypopnea syndrome based on amplitude and phase analysis of thoracic and abdominal Doppler radars

verfasst von: Masayuki Kagawa, Hirokazu Tojima, Takemi Matsui

Erschienen in: Medical & Biological Engineering & Computing | Ausgabe 5/2016

Einloggen

Aktivieren Sie unsere intelligente Suche, um passende Fachinhalte oder Patente zu finden.

search-config
loading …

Abstract

Full-night polysomnography (PSG) has been recognized as the gold standard test for sleep apnea–hypopnea syndrome (SAHS). However, PSG examinees are physically restrained for the full night by many contact sensors and obtrusive connecting cables, inducing mental stress. We developed a non-contact SAHS diagnostic system that can detect apneic events without inducing stress in monitored individuals. Two Doppler radars were installed beneath the mattress to measure the vibrations of the chest and abdomen, respectively. Our system determines apnea and hypopnea events when the radar output amplitude decreases by <20 and 70 %, respectively, of the amplitude of a normal breath (without SAHS events). Additionally, we proposed a technique that detects paradoxical movements by focusing on phase differences between thoracic and abdominal movements, and were able to identify three types of sleep apnea: obstructive, central, and mixed. Respiratory disturbance indexes obtained showed a higher correlation (r = 94 %) with PSG than with pulse oximetry (r = 89 %). When predicting the severity of SAHS with an apnea–hypopnea index (AHI) of >15/h or >30/h using PSG as a reference, the radar system achieved a sensitivity of 96 and 90 %, and a specificity of 100 and 79 % with an AHI of >15/h and >30/h, respectively. The proposed radar system can be used as an alternative to the current airflow sensor, and to chest and abdomen belts for apnea–hypopnea evaluation.

Sie haben noch keine Lizenz? Dann Informieren Sie sich jetzt über unsere Produkte:

Springer Professional "Wirtschaft+Technik"

Online-Abonnement

Mit Springer Professional "Wirtschaft+Technik" erhalten Sie Zugriff auf:

  • über 102.000 Bücher
  • über 537 Zeitschriften

aus folgenden Fachgebieten:

  • Automobil + Motoren
  • Bauwesen + Immobilien
  • Business IT + Informatik
  • Elektrotechnik + Elektronik
  • Energie + Nachhaltigkeit
  • Finance + Banking
  • Management + Führung
  • Marketing + Vertrieb
  • Maschinenbau + Werkstoffe
  • Versicherung + Risiko

Jetzt Wissensvorsprung sichern!

Springer Professional "Technik"

Online-Abonnement

Mit Springer Professional "Technik" erhalten Sie Zugriff auf:

  • über 67.000 Bücher
  • über 390 Zeitschriften

aus folgenden Fachgebieten:

  • Automobil + Motoren
  • Bauwesen + Immobilien
  • Business IT + Informatik
  • Elektrotechnik + Elektronik
  • Energie + Nachhaltigkeit
  • Maschinenbau + Werkstoffe




 

Jetzt Wissensvorsprung sichern!

Springer Professional "Wirtschaft"

Online-Abonnement

Mit Springer Professional "Wirtschaft" erhalten Sie Zugriff auf:

  • über 67.000 Bücher
  • über 340 Zeitschriften

aus folgenden Fachgebieten:

  • Bauwesen + Immobilien
  • Business IT + Informatik
  • Finance + Banking
  • Management + Führung
  • Marketing + Vertrieb
  • Versicherung + Risiko




Jetzt Wissensvorsprung sichern!

Literatur
1.
Zurück zum Zitat Andersson D, Gennser G, Johnson P (1983) Phase characteristics of breathing movements in healthy newborns. J Dev Physiol 5:289–298PubMed Andersson D, Gennser G, Johnson P (1983) Phase characteristics of breathing movements in healthy newborns. J Dev Physiol 5:289–298PubMed
2.
Zurück zum Zitat BaHammam AS, Sharif M, Gacuan DE, George S (2011) Evaluation of the accuracy of manual and automatic scoring of a single airflow channel in patients with a high probability of obstructive sleep apnea. Med Sci Monit 17:MT13–MT19CrossRefPubMedPubMedCentral BaHammam AS, Sharif M, Gacuan DE, George S (2011) Evaluation of the accuracy of manual and automatic scoring of a single airflow channel in patients with a high probability of obstructive sleep apnea. Med Sci Monit 17:MT13–MT19CrossRefPubMedPubMedCentral
3.
Zurück zum Zitat Berry RB, Budhiraja R, Gottlieb DJ, Gozal D, Iber C, Kapur VK, Marcus CL, Mehra R, Parthasarathy S, Quan SF, Redline S, Strohl KP, Davidson Ward SL, Tangredi MM (2012) Rules for scoring respiratory events in sleep: update of the 2007 AASM manual for the scoring of sleep and associated events. Deliberations of the sleep apnea definitions task force of the American Academy of Sleep Medicine. J Clin Sleep Med 8:597–619PubMedPubMedCentral Berry RB, Budhiraja R, Gottlieb DJ, Gozal D, Iber C, Kapur VK, Marcus CL, Mehra R, Parthasarathy S, Quan SF, Redline S, Strohl KP, Davidson Ward SL, Tangredi MM (2012) Rules for scoring respiratory events in sleep: update of the 2007 AASM manual for the scoring of sleep and associated events. Deliberations of the sleep apnea definitions task force of the American Academy of Sleep Medicine. J Clin Sleep Med 8:597–619PubMedPubMedCentral
4.
Zurück zum Zitat Chiner E, Signes-Costa J, Arrieiro JM, Marco J, Fuentes I, Sergado A (1999) Nocturnal oximetry for the diagnosis of the sleep apnea hypopnea syndrome. Thorax 54:968–971CrossRefPubMedPubMedCentral Chiner E, Signes-Costa J, Arrieiro JM, Marco J, Fuentes I, Sergado A (1999) Nocturnal oximetry for the diagnosis of the sleep apnea hypopnea syndrome. Thorax 54:968–971CrossRefPubMedPubMedCentral
5.
Zurück zum Zitat Choi S, Bennett LS, Mullins R, Davies RJ, Stradling JR (2000) Which derivative from overnight oximetry best predicts symptomatic response to nasal continuous positive airway pressure in patients with obstructive sleep apnoea? Respir Med 94:895–899CrossRefPubMed Choi S, Bennett LS, Mullins R, Davies RJ, Stradling JR (2000) Which derivative from overnight oximetry best predicts symptomatic response to nasal continuous positive airway pressure in patients with obstructive sleep apnoea? Respir Med 94:895–899CrossRefPubMed
6.
Zurück zum Zitat Collop NA, Tracy SL, Kapur V, Mehra R, Kuhlmann D, Fleishman SA, Ojile JM (2011) Obstructive sleep apnea devices for out-of-center (OOC) testing: technology evaluation. J Clin Sleep Med 7:531–548PubMedPubMedCentral Collop NA, Tracy SL, Kapur V, Mehra R, Kuhlmann D, Fleishman SA, Ojile JM (2011) Obstructive sleep apnea devices for out-of-center (OOC) testing: technology evaluation. J Clin Sleep Med 7:531–548PubMedPubMedCentral
7.
Zurück zum Zitat de Almeida FR, Ayas NT, Otsuka R, Ueda H, Hamilton P, Ryan FC, Lowe AA (2006) Nasal pressure recordings to detect obstructive sleep apnea. Sleep Breath 10:62–69CrossRefPubMed de Almeida FR, Ayas NT, Otsuka R, Ueda H, Hamilton P, Ryan FC, Lowe AA (2006) Nasal pressure recordings to detect obstructive sleep apnea. Sleep Breath 10:62–69CrossRefPubMed
8.
Zurück zum Zitat De Groote A, Groswasser J, Bersini H, Mathys P, Kahn A (2002) Detection of obstructive apnea events in sleeping infants from thoracoabdominal movements. J Sleep Res 11:161–168CrossRefPubMed De Groote A, Groswasser J, Bersini H, Mathys P, Kahn A (2002) Detection of obstructive apnea events in sleeping infants from thoracoabdominal movements. J Sleep Res 11:161–168CrossRefPubMed
9.
Zurück zum Zitat Dei D, Grazzini G, Luzi G, Pieraccini M, Atzeni C, Boncinelli S, Camiciottoli G, Castellani W, Marsili M, Dico JL (2009) Non-contact detection of breathing using a microwave sensor. Sensors 9:2574–2585CrossRefPubMedPubMedCentral Dei D, Grazzini G, Luzi G, Pieraccini M, Atzeni C, Boncinelli S, Camiciottoli G, Castellani W, Marsili M, Dico JL (2009) Non-contact detection of breathing using a microwave sensor. Sensors 9:2574–2585CrossRefPubMedPubMedCentral
10.
Zurück zum Zitat Droitcour AD, Boric-Lubecke O, Lubecke VM, Lin J, Kovacs GTA (2004) Range correlation and I/Q performance benefits in single-chip silicon Doppler radars for noncontact cardiopulmonary monitoring. IEEE Trans Microw Theory Tech 52:838–848CrossRef Droitcour AD, Boric-Lubecke O, Lubecke VM, Lin J, Kovacs GTA (2004) Range correlation and I/Q performance benefits in single-chip silicon Doppler radars for noncontact cardiopulmonary monitoring. IEEE Trans Microw Theory Tech 52:838–848CrossRef
11.
Zurück zum Zitat Epstein LJ, Kristo D, Strollo PJ Jr, Friedman N, Malhotra A, Patil SP, Ramar K, Rogers R, Schwab RJ, Weaver EM, Weinstein MD (2009) Clinical guideline for the evaluation, management and long-term care of obstructive sleep apnea in adults. J Clin Sleep Med 5:263–276PubMed Epstein LJ, Kristo D, Strollo PJ Jr, Friedman N, Malhotra A, Patil SP, Ramar K, Rogers R, Schwab RJ, Weaver EM, Weinstein MD (2009) Clinical guideline for the evaluation, management and long-term care of obstructive sleep apnea in adults. J Clin Sleep Med 5:263–276PubMed
12.
Zurück zum Zitat Flemons WW, Littner MR, Rowley JA, Gay P, Anderson WM, Hudgel DW, McEvoy RD, Loube DI (2003) Home diagnosis of sleep apnea: a systematic review of the literature. Chest 124:1543–1579CrossRefPubMed Flemons WW, Littner MR, Rowley JA, Gay P, Anderson WM, Hudgel DW, McEvoy RD, Loube DI (2003) Home diagnosis of sleep apnea: a systematic review of the literature. Chest 124:1543–1579CrossRefPubMed
13.
Zurück zum Zitat Gutiérrez-Tobal GC, Hornero R, Alvarez D, Marcos JV, del Campo F (2012) Linear and nonlinear analysis of airflow recordings to help in sleep apnoea-hypopnoea syndrome diagnosis. Physiol Meas 33:1261–1275CrossRefPubMed Gutiérrez-Tobal GC, Hornero R, Alvarez D, Marcos JV, del Campo F (2012) Linear and nonlinear analysis of airflow recordings to help in sleep apnoea-hypopnoea syndrome diagnosis. Physiol Meas 33:1261–1275CrossRefPubMed
14.
Zurück zum Zitat Gutiérrez-Tobal GC, Álvarez D, Marcos JV, del Campo F, Hornero R (2013) Pattern recognition in airflow recordings to assist in the sleep apnoea-hypopnoea syndrome diagnosis. Med Biol Eng Comput 51:1367–1380CrossRefPubMed Gutiérrez-Tobal GC, Álvarez D, Marcos JV, del Campo F, Hornero R (2013) Pattern recognition in airflow recordings to assist in the sleep apnoea-hypopnoea syndrome diagnosis. Med Biol Eng Comput 51:1367–1380CrossRefPubMed
15.
Zurück zum Zitat Hammer J, Newth CJ (2009) Assessment of thoraco-abdominal asynchrony. Paediatr Respir Rev 10:75–80CrossRefPubMed Hammer J, Newth CJ (2009) Assessment of thoraco-abdominal asynchrony. Paediatr Respir Rev 10:75–80CrossRefPubMed
16.
Zurück zum Zitat Hornero R, Alvarez D, Abásolo D, del Campo F, Zamarrón C (2007) Utility of approximate entropy from overnight pulse oximetry data in the diagnosis of the obstructive sleep apnea syndrome. IEEE Trans Biomed Eng 54:107–113CrossRefPubMed Hornero R, Alvarez D, Abásolo D, del Campo F, Zamarrón C (2007) Utility of approximate entropy from overnight pulse oximetry data in the diagnosis of the obstructive sleep apnea syndrome. IEEE Trans Biomed Eng 54:107–113CrossRefPubMed
17.
Zurück zum Zitat Kagawa M, Yoshida Y, Kubota M, Kurita A, Matsui T (2012) Non-contact heart rate monitoring method for elderly people in bed with random body motions using 24 GHz dual radars located beneath the mattress in clinical settings. J Med Eng Technol 36:344–350CrossRefPubMed Kagawa M, Yoshida Y, Kubota M, Kurita A, Matsui T (2012) Non-contact heart rate monitoring method for elderly people in bed with random body motions using 24 GHz dual radars located beneath the mattress in clinical settings. J Med Eng Technol 36:344–350CrossRefPubMed
18.
Zurück zum Zitat Lévy P, Pépin JL, Deschaux-Blanc C, Paramelle B, Brambilla C (1996) Accuracy of oximetry for detection of respiratory disturbances in sleep apnea syndrome. Chest 109:395–399CrossRefPubMed Lévy P, Pépin JL, Deschaux-Blanc C, Paramelle B, Brambilla C (1996) Accuracy of oximetry for detection of respiratory disturbances in sleep apnea syndrome. Chest 109:395–399CrossRefPubMed
19.
Zurück zum Zitat Lin CL, Yeh C, Yen CW, Hsu WH, Hang LW (2009) Comparison of the indices of oxyhemoglobin saturation by pulse oximetry in obstructive sleep apnea hypopnea syndrome. Chest 135:86–93CrossRefPubMed Lin CL, Yeh C, Yen CW, Hsu WH, Hang LW (2009) Comparison of the indices of oxyhemoglobin saturation by pulse oximetry in obstructive sleep apnea hypopnea syndrome. Chest 135:86–93CrossRefPubMed
20.
Zurück zum Zitat Massagram W, Hafner N, Lubecke V, Boric-Lubecke O (2013) Tidal volume measurement through non-contact Doppler radar with DC reconstruction. Sens J IEEE 13:3397–3404CrossRef Massagram W, Hafner N, Lubecke V, Boric-Lubecke O (2013) Tidal volume measurement through non-contact Doppler radar with DC reconstruction. Sens J IEEE 13:3397–3404CrossRef
21.
Zurück zum Zitat Motto AL, Galiana HL, Brown KA, Kearney RE (2005) Automated estimation of the phase between thoracic and abdominal movement signals. IEEE Trans Biomed Eng 52:614–621CrossRefPubMed Motto AL, Galiana HL, Brown KA, Kearney RE (2005) Automated estimation of the phase between thoracic and abdominal movement signals. IEEE Trans Biomed Eng 52:614–621CrossRefPubMed
22.
Zurück zum Zitat Nakano H, Ikeda T, Hayashi M, Ohshima E, Itoh M, Nishikata N, Shinohara T (2004) Effect of body mass index on overnight oximetry for the diagnosis of sleep apnea. Respir Med 98:421–427CrossRefPubMed Nakano H, Ikeda T, Hayashi M, Ohshima E, Itoh M, Nishikata N, Shinohara T (2004) Effect of body mass index on overnight oximetry for the diagnosis of sleep apnea. Respir Med 98:421–427CrossRefPubMed
23.
Zurück zum Zitat Nakano H, Tanigawa T, Furukawa T, Nishima S (2007) Automatic detection of sleep-disordered breathing from a single-channel airflow record. Eur Respir J 29:728–736CrossRefPubMed Nakano H, Tanigawa T, Furukawa T, Nishima S (2007) Automatic detection of sleep-disordered breathing from a single-channel airflow record. Eur Respir J 29:728–736CrossRefPubMed
24.
Zurück zum Zitat Prisk GK, Hammer J, Newth CJ (2002) Techniques for measurement of thoracoabdominal asynchrony. Pediatr Pulmonol 34:462–472CrossRefPubMed Prisk GK, Hammer J, Newth CJ (2002) Techniques for measurement of thoracoabdominal asynchrony. Pediatr Pulmonol 34:462–472CrossRefPubMed
25.
Zurück zum Zitat Sivan Y, Ward SD, Deakers T, Keens TG, Newth CJ (1991) Rib cage to abdominal asynchrony in children undergoing polygraphic sleep studies. Pediatr Pulmonol 11:141–146CrossRefPubMed Sivan Y, Ward SD, Deakers T, Keens TG, Newth CJ (1991) Rib cage to abdominal asynchrony in children undergoing polygraphic sleep studies. Pediatr Pulmonol 11:141–146CrossRefPubMed
26.
Zurück zum Zitat Staats BA, Bonekat HW, Harris CD, Offord KP (1984) Chest wall motion in sleep apnea. Am Rev Respir Dis 130:59–63PubMed Staats BA, Bonekat HW, Harris CD, Offord KP (1984) Chest wall motion in sleep apnea. Am Rev Respir Dis 130:59–63PubMed
27.
Zurück zum Zitat Yadollahi A, Giannouli E, Moussavi Z (2010) Sleep apnea monitoring and diagnosis based on pulse oximetry and tracheal sound signals. Med Biol Eng Comput 48:1087–1097CrossRefPubMed Yadollahi A, Giannouli E, Moussavi Z (2010) Sleep apnea monitoring and diagnosis based on pulse oximetry and tracheal sound signals. Med Biol Eng Comput 48:1087–1097CrossRefPubMed
28.
Zurück zum Zitat Young T, Palta M, Dempsey J, Skatrud J, Weber S, Badr S (1993) The occurrence of sleep-disordered breathing among middle-aged adults. N Engl J Med 328:1230–1235CrossRefPubMed Young T, Palta M, Dempsey J, Skatrud J, Weber S, Badr S (1993) The occurrence of sleep-disordered breathing among middle-aged adults. N Engl J Med 328:1230–1235CrossRefPubMed
Metadaten
Titel
Non-contact diagnostic system for sleep apnea–hypopnea syndrome based on amplitude and phase analysis of thoracic and abdominal Doppler radars
verfasst von
Masayuki Kagawa
Hirokazu Tojima
Takemi Matsui
Publikationsdatum
01.05.2016
Verlag
Springer Berlin Heidelberg
Erschienen in
Medical & Biological Engineering & Computing / Ausgabe 5/2016
Print ISSN: 0140-0118
Elektronische ISSN: 1741-0444
DOI
https://doi.org/10.1007/s11517-015-1370-z

Weitere Artikel der Ausgabe 5/2016

Medical & Biological Engineering & Computing 5/2016 Zur Ausgabe