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Journal of Nanoparticle Research
Erschienen in: Journal of Nanoparticle Research 7/2017

01.07.2017 | Review

Magnetic nanoparticles: reactive oxygen species generation and potential therapeutic applications

verfasst von: Trang Mai, J. Zach Hilt

Erschienen in: Journal of Nanoparticle Research | Ausgabe 7/2017

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Abstract

Magnetic nanoparticles have been demonstrated to produce reactive oxygen species (ROS), which play a major role in various cellular pathways, via Fenton and Haber-Weiss reaction. ROS act as a double-edged sword inside the body. At normal conditions, the generation of ROS is in balance with their elimination by scavenger systems, and they can promote cell proliferation as well as differentiation. However, at an increased level, they can cause damages to protein, lead to cellular apoptosis, and contribute to many diseases including cancer. Many recent studies proposed a variety of strategies to either suppress toxicity of ROS generation or exploit the elevated ROS levels for cancer therapy.
Vorheriger Artikel A framing theory-based content analysis of a Turkish newspaper’s coverage of nanotechnology
Nächster Artikel Structures and orientation-dependent interaction forces of titania nanowires using molecular dynamics simulations

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Metadaten
Titel
Magnetic nanoparticles: reactive oxygen species generation and potential therapeutic applications
verfasst von
Trang Mai
J. Zach Hilt
Publikationsdatum
01.07.2017
Verlag
Springer Netherlands
Erschienen in
Journal of Nanoparticle Research / Ausgabe 7/2017
Print ISSN: 1388-0764
Elektronische ISSN: 1572-896X
DOI
https://doi.org/10.1007/s11051-017-3943-2

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