Mathematical Modelling of the Immune Response: A Model of The Proliferation Control

The successful immune response to given antigen is manifested by elimination of antigen; generation of antibody forming cells and production of antibody (if humoral response) or cytotoxic cells (if cellular immunity); and generation of memory cells. Memory cells remain in the organism after primary response, and they prove that the secondary response is more efficient. Such a process is the result of an intricate interaction within the multicomponent immune system. Although at the present time all major components (cell populations) which take part in the immune response are probably known, the question how these components interact during the course of the immune response has not been solved satisfactorily yet. In our model we have tried to formulate the relations between cell populations taking part in the immune response, which seemed to be substantial for its proper function.