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Quality of Life Research

Erschienen in:

01.05.2012

Measuring health-related quality-of-life for Alzheimer’s disease using the general public

verfasst von: Feng Xie, Mark Oremus, Kathryn Gaebel

Erschienen in: Quality of Life Research | Ausgabe 4/2012

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Abstract

Purpose

Little research exists to indicate whether the general public can provide proxy health-related quality-of-life (HRQoL) estimates for persons with Alzheimer’s disease (AD). We investigated (1) whether the general public can differentiate between mild, moderate, and severe AD and (2) whether the general public’s proxy HRQoL estimates are correlated with current health status.

Methods

We conducted computer-assisted personal interviews. The computer randomly assigned each participant to read a vignette describing mild, moderate, or severe AD. Participants answered the EQ-5D-5L and Quality-of-life-Alzheimer’s Disease (QoL-AD), while imagining living in the health state described in their assigned vignette. Participants also answered the EQ-5D-5L based on their health state at the time of the interview.

Results

We interviewed 100 participants. EQ-5D-5L utilities were 0.7413 (mild), 0.6159 (moderate), and 0.4456 (severe) (P < 0.001). Mean QoL-AD scores were 32.5 (mild), 24.0 (moderate), and 21.8 (severe) (P < 0.0001 for severe vs. mild, moderate vs. mild; P > 0.05 for severe vs. moderate). Participants’ EQ-5D-5L utility scores were weakly correlated (r ≤ 0.28) across both administrations of the instrument.

Conclusions

The general public can differentiate between the three stages of AD, and their HRQoL estimates for AD are weakly correlated with their current health status.

Vorheriger Artikel Influence of chronic diseases on long-term change in physical health: a consultation–survey linkage cohort study in general practice

Nächster Artikel Assessment of the psychological burden associated with pruritus in hemodialysis patients using the kidney disease quality of life short form

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Titel: Measuring health-related quality-of-life for Alzheimer’s disease using the general public
verfasst von: Feng Xie
Mark Oremus
Kathryn Gaebel
Publikationsdatum: 01.05.2012
Verlag: Springer Netherlands
Erschienen in: Quality of Life Research / Ausgabe 4/2012
Print ISSN: 0962-9343
Elektronische ISSN: 1573-2649
DOI: https://doi.org/10.1007/s11136-011-9966-8

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Abstract

Purpose

Methods

Results

Conclusions

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