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Erschienen in:
2007 | OriginalPaper | Buchkapitel
Medical and Technical Protocol for Automatic Navigation of a Wireless Device in the Carotid Artery of a Living Swine Using a Standard Clinical MRI System
verfasst von : Sylvain Martel, Jean-Baptiste Mathieu, Ouajdi Felfoul, Arnaud Chanu, Eric Aboussouan, Samer Tamaz, Pierre Pouponneau, L’Hocine Yahia, Gilles Beaudoin, Gilles Soulez, Martin Mankiewicz
Erschienen in: Medical Image Computing and Computer-Assisted Intervention – MICCAI 2007
Verlag: Springer Berlin Heidelberg
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A 1.5 mm magnetic sphere was navigated automatically inside the carotid artery of a living swine. The propulsion force, tracking and real-time capabilities of a Magnetic Resonance Imaging (MRI) system were integrated into a closed loop control platform. The sphere was released using an endovascular catheter approach. Specially developed software is responsible for the tracking, propulsion, event timing and closed loop position control in order to follow a 10 roundtrips preplanned trajectory on a distance of 5 cm inside the right carotid artery of the animal. Experimental protocol linking the technical aspects of this
in vivo
assay is presented. In the context of this demonstration, many challenges which provide insights about concrete issues of future nanomedical interventions and interventional platforms have been identified and addressed.