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Erschienen in:
2014 | OriginalPaper | Buchkapitel
Mesoscopic Models for the Overstretching Transition of DNA
verfasst von : Ana Elisa Bergues Pupo, Alessandro Fiasconaro, Fernando Falo
Erschienen in: Extended Abstracts Spring 2013
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Abstract
One of the most intriguing and only partially clear phenomenon concerning the mechanical properties of DNA is the so-called overstretching transition [2, 7]. It consists in a sudden elongation of the DNA chain of about 70 % more than the native length (B-DNA), when a force around 70 pN is applied. Three main mechanisms have been proposed to explain this transition. Two of them involve breaking of the bonds that hold the two strands together: peeling from nicks or free ends of the chain; and inside-strand separation (M-DNA) [10–12].