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Journal of Materials Engineering and Performance

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14.03.2022 | Technical Article

Microstructure, Mechanical Properties, and Cytotoxicity of β-Type Ti-Nb-Cr Alloys Designed by Electron Parameter

verfasst von: Qiang Li, Fei Li, Junjie Li, Zhi Gao, Ke Zhang, Mitsuo Niinomi, Takayoshi Nakano

Erschienen in: Journal of Materials Engineering and Performance | Ausgabe 6/2022

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Abstract

A series of β-type Ti-(24-2x)Nb-xCr (at%) (x=0, 1, 2, 3, 4, 5) alloys were designed by using Cr to replace Nb with a fixing average valence electron number (valence electron/atom ratio, e/a ratio) of 4.24. The alloys were prepared by arc melting and then subjected to homogenization, cold rolling and solution treatment. The phases and microstructures were analyzed by x-ray diffraction and optical microscopy. The mechanical properties were measured by tensile tests. The cytotoxicity was evaluated by detecting the proliferation of MC3T3-E1 cells after several days' culture. With the increase of Cr content, the β stability of the studied Ti-Nb-Cr alloys is gradually increased. Stress-induced martensite transformation is found in Ti-24Nb and Ti-22Nb-1Cr and suppressed by more Cr addition. Nonlinear deformation and twinning appear in all the alloys indicating that the β phases are all metastable. The 0.2 % proof stress increases with increase of Cr owing the enhanced β stability and solid solution strengthening effect due to Cr addition. Obvious dynamic reinforcement during deformation is found in Ti-22Nb-1Cr leading to higher tensile strength than those of Ti-24Nb and Ti-20Nb-2Cr. The tensile strength continuous increases with Cr content increasing from 2 to 5 %. Cytotoxicity is not found in Ti-24Nb and Ti-16Nb-4Cr by observing the growth of mice pre-osteoblast line MC3T3-E1. Ti-16Nb-4Cr shows good comprehensive mechanical properties and non-cytotoxicity, and is a potential candidate for biomaterials.

Vorheriger Artikel Comparative Capabilities of Conventional and Ultrasonic-Assisted-Electrical Discharge Machining of Nimonic Alloy 75

Nächster Artikel Forming Appearance Analysis of 2205 Duplex Stainless Steel Fabricated by Cold Metal Transfer (CMT) Based Wire and Arc Additive Manufacture (WAAM) Process

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M. Geetha, A.K. Singh, R. Asokamani and A.K. Gogia, Ti Based Biomaterials, the Ultimate Choice for Orthopaedic Implants -A Review, Prog. Mater. Sci., 2009, 54, p 397–425. https://doi.org/10.1016/j.pmatsci.2008.06.004CrossRef

Q.Z. Chen and G.A. Thouas, Metallic Implant Biomaterials, Mater. Sci. Eng. R, 2015, 87, p 1–57. https://doi.org/10.1016/j.mser.2014.10.001CrossRef

M. Balazic, J. Kopac, M.J. Jackson and W. Ahmed, Review: Titanium and Titanium Alloy Applications in Medicine, Int. J. Nano Biomater., 2007, 1, p 3–34. https://doi.org/10.1504/IJNBM.2007.016517CrossRef

A. Revathi, S. Magesh, V.K. Balla, M. Das and G. Manivasagam, Current Advances in Enhancement of Wear and Corrosion Resistance of Titanium Alloys - A Review, Mater. Technol., 2016, 31, p 696–704. https://doi.org/10.1080/10667857.2016.1212780CrossRef

H. Liu, J.J. Yang, X.Y. Zhao, Y.Y. Sheng, W. Li, C.L. Chang, Q. Zhang, Z.T. Yu and X.J. Wang, Microstructure, Mechanical Properties and Corrosion Behaviors of Biomedical Ti-Zr-Mo-xMn Alloys for Dental Application, Corros. Sci., 2019, 161, 108195. https://doi.org/10.1016/j.corsci.2019.108195CrossRef

Y. Qu, S. Zheng, R.P. Dong, M.Y. Kang, H.H. Zhou, D.Z. Zhao and J.W. Zhao, Ti-24Nb-4Zr-8Sn Alloy Pedicle Screw Improves Internal Vertebral Fixation by Reducing Stress-Shielding Effects in a Porcine Model, Biomed Res. Int., 2018, 2018, p 13. https://doi.org/10.1155/2018/8639648CrossRef

Y.J. Bai, Y. Deng, Y.F. Zheng, Y.L. Li, R.R. Zhang, Y.L. Lv, Q. Zhao and S.C. Wei, Characterization, Corrosion Behavior, Cellular Response and In vivo Bone Tissue Compatibility of Titanium - Niobium Alloy with Low Young’s Modulus, Mater. Sci. Eng. C, 2016, 59, p 565–576. https://doi.org/10.1016/j.msec.2015.10.062CrossRef

Y.D. Xu, J.H. Gao, Y.H. Huang and W.M. Rainforth, A Low-cost Metastable Beta Ti-Alloy with High Elastic Admissible Strain and Enhanced Ductility for Orthopaedic Application, J. Alloys Compd., 2020, 835, 155391. https://doi.org/10.1016/j.jallcom.2020.155391CrossRef

K. Klotz, W. Weistenhöfer, F. Neff, A. Hartwig, C.V. Thriel and H. Drexler, The Health Effects of Aluminum Exposure, Dtsch Arztebl Int, 2017, 114, p 653–659. https://doi.org/10.3238/arztebl.2017.0653CrossRef

10.

J. Markhoff, M. Krogull, C. Schulze, C. Rotsch, S. Hunger and R. Bader, Biocompatibility and Inflammatory Potential of Titanium Alloys Cultivated with Human Osteoblasts, Fibroblasts and Macrophages, Materials, 2017, 10, p 52. https://doi.org/10.3390/ma10010052CrossRef

11.

A. Biesiekierski, J.X. Lin, Y.C. Li, D. Ping, Y. Yamabe-Mitarai and C. Wen, Impact of Ruthenium on Mechanical Properties, Biological Response and Thermal Processing of β-type Ti-Nb-Ru Alloys, Acta Biomater., 2017, 48, p 461–467. https://doi.org/10.1016/j.actbio.2016.09.012CrossRef

12.

F.F. de Quadros, P.A.B. Kuroda, K.S.J. dos Sousa, T.A.G. Donato and C.R. Grandini, Preparation, Structural and Microstructural Characterization of Ti-25Ta-10Zr Alloy for Biomedical Applications, J. Mater. Res. Technol., 2019, 8, p 4108–4114. https://doi.org/10.1016/j.jmrt.2019.07.020CrossRef

13.

M.A. Hussein, C. Suryanarayana and N. Al-aqeeli, Fabrication of Nano-grained Ti-Nb-Zr Biomaterials Using Spark Plasma Sintering, Mater. Des., 2015, 87, p 693–700. https://doi.org/10.1016/j.matdes.2015.08.082CrossRef

14.

C. Oldani and A. Dominguez, Titanium as a biomaterial for implants, Intech Open Access Publisher, London, 2012.CrossRef

15.

A.H.G. Mohamed, I. Mervat and S. Kobayashi, Low Young’s Modulus β-Ti-Alloys for Biomedical Applications, Adv. Mater. Res., 2014, 124, p 308–311. https://doi.org/10.4028/www.scientific.net/AMR.1024.308CrossRef

16.

B.B. Zhang, B.L. Wang, Y.B. Wang, L. Li, Y.F. Zheng and Y. Liu, Development of Ti-Ag-Fe Ternary Titanium Alloy for Dental Application, J. Biomed. Mater. Res., Part B, 2012, 100B, p 185–196. https://doi.org/10.1002/jbm.b.31937CrossRef

17.

G. Senopati, C. Sutowo, P.A. Ing, E.P. Utomo and M.I. Amal, Microstructure and mechanical properties of as-cast Ti-Mo-xCr alloy for biomedical application, AIP Publishing LLC, Melville, 2016.CrossRef

18.

Z. Chen, Y. Liu, H. Jiang, M. Liu, C.H. Wang and G.H. Cao, Microstructures and Mechanical Properties of Mn Modified, Ti-Nb Based Alloys, J. Alloys Compd., 2017, 723, p 1091–1097. https://doi.org/10.1016/j.jallcom.2017.06.311CrossRef

19.

M.L. Loureno, G.C. Cardoso, K. Sousa, T. Donato and C.R. Grandini, Development of Novel Ti-Mo-Mn Alloys for Biomedical Applications, Sci. Rep., 2020, 10, p 1–8. https://doi.org/10.1038/s41598-020-62865-4CrossRef

20.

Y.T. Li, D.L. Ma, H.Y. Liu, P.P. Jing, Y.L. Gong, Z. Ayaz, F.J. Jing, X. Jiang and Y.X. Leng, Biocompatibility of Ti-Mn-N Films with Different Manganese Contents, Surf. Coat. Technol., 2020, 403, p 126354. https://doi.org/10.1016/j.surfcoat.2020.126354CrossRef

21.

M. Alqattan, L. Peters, Y. Alshammari, F. Yang and L. Bolzoni, Antibacterial Ti-Mn-Cu Alloys for Biomedical Applications, Regener. Biomater., 2020, 8, p 1–8. https://doi.org/10.1093/rb/rbaa050CrossRef

22.

B.S. Lou, Y.C. Yang, J.W. Lee and L.T. Chen, Biocompatibility and Mechanical Property Evaluation of Zr-Ti-Fe Based Ternary thin Film Metallic Glasses, Surf. Coat. Technol., 2017, 320, p 512–519. https://doi.org/10.1016/j.surfcoat.2016.11.039CrossRef

23.

J.Z. Niu, Y.H. Guo, K. Li, W.J. Liu, Z.H. Dan, Z.G. Sun, H. Chang and L. Zhou, Improved Mechanical, Bio-corrosion Properties and In vitro Cell Responses of Ti-Fe Alloys as Candidate Dental Implants, Mater. Sci. Eng. C, 2021, 122, p 111917. https://doi.org/10.1016/j.msec.2021.111917CrossRef

24.

X.F. Zhao, M. Niinomi, M. Nakai, J. Hieda, T. Ishimoto and T. Nakano, Optimization of Cr Content of Metastable β-type Ti-Cr Alloys with Changeable Young’s Modulus for Spinal Fixation Applications, Acta Biomater., 2012, 8, p 2392–2400. https://doi.org/10.1016/j.actbio.2012.02.010CrossRef

25.

Y. Alshammari, F. Yang and L. Bolzoni, Mechanical Properties and Microstructure of Ti-Mn Alloys Produced via Powder Metallurgy for Biomedical Applications, J. Mech. Behav. Biomed. Mater., 2019, 91, p 391–397. https://doi.org/10.1016/j.jmbbm.2018.12.005CrossRef

26.

M.K. Gouda, K. Nakamura and M.A.H. Gepreel, Effect of Mn-Content on the Deformation Behavior of Binary Ti-Mn Alloys, Key Eng. Mater., 2016, 705, p 214–218. https://doi.org/10.4028/www.scientific.net/KEM.705.214CrossRef

27.

M.K. Gouda, M.A.H. Gepreel, K. Yamanaka, H. Bian, K. Nakamura and A. Chiba, Cold-Workability and Microstructure Change with β-Phase Stability in High-Strength Ti-Mn Binary Alloys, JOM, 2019, 71, p 3590–3599. https://doi.org/10.1007/s11837-019-03690-7CrossRef

28.

Y. Bao, M. Zhang, Y. Liu, J.J. Yao, Z.M. Xiu, M. Xie and X.D. Sun, High Strength, Low Modulus and Biocompatible Porous Ti-Mo-Fe Alloys, J. Porous Mater., 2014, 21, p 913–919. https://doi.org/10.1007/s10934-014-9837-0CrossRef

29.

Q. Li, G.H. Ma, J.J. Li, M. Niinomi, M. Nakai, Y. Koizumi, D.X. Wei, T. Kakeshita, T. Nakano, A. Chiba, X.Y. Liu, K. Zhou and D. Pan, Development of Low-Young’s Modulus Ti-Nb-Based Alloys with Cr Addition, J. Mater. Sci., 2019, 54, p 8675–8683. https://doi.org/10.1007/s10853-019-03457-0CrossRef

30.

G.Y. Yoo, C.H. Park, J.-K. Hong, S.-E. Kim, N.H. Kang and J.-T. Yeom, Effect of Beta Stabilizer Content on Young’s Moduli of Titanium Alloys with Similar Electronic States, Korean J. Met. Mater., 2013, 51, p 307–315. https://doi.org/10.3365/KJMM.2013.51.4.307CrossRef

31.

Q. Li, M. Niinomi, M. Nakai, Z.D. Cui, S.L. Zhu and X.J. Yang, Effect of Zr on Super-Elasticity and Mechanical Properties of Ti-24 at% Nb- (0, 2,4) at% Zr Alloy Subjected to Aging Treatment, J. Mater. Sci. Eng. A, 2012, 536, p 197–206. https://doi.org/10.1016/j.msea.2011.12.103CrossRef

32.

R.P. Kolli, W.J. Joost and S. Ankem, Phase Stability and Stress-Induced Transformations in Beta Titanium Alloys, JOM, 2015, 67, p 1273–1280. https://doi.org/10.1007/s11837-015-1411-yCrossRef

33.

J.H. Gao, Y.H. Huang, D.K. Guan, A.J. Knowles, L. Ma, D. Dye and W.M. Rainforth, Deformation Mechanisms in a Metastable Beta Titanium Twinning Induced Plasticity Alloy with High Yield Strength and High Strain Hardening Rate, Acta Biomater., 2018, 152, p 301–314. https://doi.org/10.1016/j.actamat.2018.04.035CrossRef

34.

S.E. Haghighi, Y.J. Liu, G.H. Cao and L.C. Zhang, Phase Transition, Microstructural Evolution and Mechanical Properties of Ti-Nb-Fe Alloys Induced by Fe Addition, Mater. Des., 2016, 97, p 279–286. https://doi.org/10.1016/j.matdes.2016.02.094CrossRef

35.

Y.L. Hao, S.J. Li, S.Y. Sun and R. Yang, Effect of Zr and Sn on Young’s Modulus and Superelasticity of Ti-Nb-Based Alloys, Mater. Sci. Eng. A, 2006, 441, p 112–118. https://doi.org/10.1016/j.msea.2006.09.051CrossRef

36.

M. Abdel-Hady, K. Hinoshita and M. Morinaga, General Approach to Phase Stability and Elastic Properties of β-Type Ti-Alloys Using Electronic Parameter, Scr. Mater., 2006, 55, p 477–480. https://doi.org/10.1016/j.scriptamat.2006.04.022CrossRef

37.

M.J. Lai, C.C. Tasan and D. Raabe, On the Mechanism of 332 Twinning in Metastable β Titanium Alloys, Acta Mater., 2016, 111, p 173–186. https://doi.org/10.1016/j.actamat.2016.03.040CrossRef

38.

X.H. Min, X.J. Chen, S. Emura and K. Tsuchiya, Mechanism of Twinning-Induced Plasticity in β-type Ti-15Mo Alloy, Scr. Mater., 2013, 69, p 393–396. https://doi.org/10.1016/j.scriptamat.2013.05.027CrossRef

39.

Y. Mantani, Y. Takemoto, M. Hida and A. Sakakibara, Formation of a″ Martensite and {332}<113>β Twin During Tensile Deformation in Ti-40 Mass% Nb Alloy, J. Jpn. I. Met., 2002, 10, p 1022–1029. https://doi.org/10.1002/ajh.10189CrossRef

40.

D. Kuroda, M. Niinomi, M. Morinaga, Y. Kato and T. Yashiro, Design and Mechanical Properties of New β Type Titanium Alloys for Implant Materials, Mater. Sci. Eng. A, 1998, 243, p 244–249. https://doi.org/10.1016/S0921-5093(97)00808-3CrossRef

41.

M. Geetha, A.K. Singh, R. Asokamani and A.K. Gogia, Ti Based Biomaterials, the Ultimate Choice for Orthopaedic Implants-A Review, Prog. Mater Sci., 2009, 54, p 397–425. https://doi.org/10.1016/j.pmatsci.2008.06.004CrossRef

42.

S.F. Jawed, C.D. Rabadia, Y.J. Liu, L.Q. Wang, Y.H. Li, X.H. Zhang and L.C. Zhang, Beta-type Ti-Nb-Zr-Cr Alloys with Large Plasticity and Significant Strain Hardening, Mater. Des., 2019, 181, 108064. https://doi.org/10.1016/j.matdes.2019.108064CrossRef

Titel: Microstructure, Mechanical Properties, and Cytotoxicity of β-Type Ti-Nb-Cr Alloys Designed by Electron Parameter
verfasst von: Qiang Li
Fei Li
Junjie Li
Zhi Gao
Ke Zhang
Mitsuo Niinomi
Takayoshi Nakano
Publikationsdatum: 14.03.2022
Verlag: Springer US
Erschienen in: Journal of Materials Engineering and Performance / Ausgabe 6/2022
Print ISSN: 1059-9495
Elektronische ISSN: 1544-1024
DOI: https://doi.org/10.1007/s11665-022-06586-x

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