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Erschienen in:
2008 | OriginalPaper | Buchkapitel
Multichromosomal Genome Median and Halving Problems
verfasst von : Eric Tannier, Chunfang Zheng, David Sankoff
Erschienen in: Algorithms in Bioinformatics
Verlag: Springer Berlin Heidelberg
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Genome median and halving problems aim at reconstructing ancestral genomes and the evolutionary events leading from the ancestor to extant species. The NP-hardness of the breakpoint distance and reversal distance median problems for unichromosomal genomes do not easily imply the same for the multichromosomal case. Here we find the complexity of several genome median and halving problems, including a surprising polynomial result for the breakpoint median and guided halving problems in genomes with circular and linear chromosomes; the multichromosomal problem is thus easier than the unichromosomal one.