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Erschienen in:
Microscale Technologies for Engineering Complex Tissue Structures Kapitel lesen Erstes Kapitel lesen

2016 | OriginalPaper | Buchkapitel

13. Nano- and Microscale Delivery Systems for Cardiovascular Therapy

verfasst von : Renae Waters, Ryan Maloney, Sudhir H. Ranganath, Hsin-Yi Hsieh, Arghya Paul

Erschienen in: Microscale Technologies for Cell Engineering

Verlag: Springer International Publishing

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Abstract

Cardiovascular disease is still a major healthcare concern as it continues to be the leading cause of death in developed countries. Recent advancement in bioengineering technologies to generate micro- and nanoscale materials as biotransporters and therapeutics has led to a variety of new approaches to treat cardiovascular diseases. Although these strategies are still in their initial stage of research, developing effective alternate therapies to treat life-threatening diseases such as myocardial infarction and atherosclerosis can potentially improve patient outcomes and long-term economic costs imposed on the healthcare system. Over the last decade, a wide array of materials with tunable biophysical and chemical properties has been developed to successfully deliver therapeutic agents such as nucleic acids, proteins, and small molecules, and even stem cells in combination with nanomaterials for advanced cardiovascular treatments. This mainly includes polymeric nanoparticles and nanohybrid materials, microparticles, carbon nanotubes, graphene oxide, liposomes, microgels, nanofibers, and nanoscaffolds. In addition, these materials also find application as multifunctional theranostic nanoagents which combine in vivo diagnostic properties along with therapeutic capabilities. This chapter discusses the emerging therapeutic delivery systems for biomedical research and highlights the recent developments in this highly interdisciplinary field along with examples of strategies that hold promise for the future of cardiovascular medicine.

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Vorheriges Kapitel Engineering Mechanical, Biochemical, and Topographical Niche Cues by Photocrosslinkable, Microribbon-Like Hydrogels
Nächstes Kapitel Nanoparticulate Systems for Controlling Monocyte/Macrophage Behavior
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Metadaten
Titel
Nano- and Microscale Delivery Systems for Cardiovascular Therapy
verfasst von
Renae Waters
Ryan Maloney
Sudhir H. Ranganath
Hsin-Yi Hsieh
Arghya Paul
Copyright-Jahr
2016
Buch
Microscale Technologies for Cell Engineering

Print ISBN: 978-3-319-20725-4

Electronic ISBN: 978-3-319-20726-1

Copyright-Jahr: 2016

DOI
https://doi.org/10.1007/978-3-319-20726-1_13

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