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2020 | OriginalPaper | Buchkapitel

15. Nanozymes for Antimicrobes: Precision Biocide

verfasst von : Zhuobin Xu, Dandan Li, Zhiyue Qiu, Lizeng Gao

Erschienen in: Nanozymology

Verlag: Springer Singapore

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Abstract

Nanozymes have been used to dealing with microbes and remarkable advances have been made in various areas. Nanozymes with peroxidase-activity such as CeO₂ nanoparticles are used for colorimetric sensing of bacteria when integrated with detection antibody, which is much more rapid and lower-cost than traditional methods. Oxidase-mimic nanozymes such as Au nanoparticles (AuNP) are able to generate reactive oxide species (ROS) for killing bacteria. Plenty of nanozymes with peroxidase-activity, such as magnetic iron oxide, grapheme quantum dots have been used for combating bacteria, biofilms as well as practical wound disinfection and healing, through catalyzing H₂O₂ into highly toxic hydroxyl radical that can degrade the biofilm matrix and effectively kill the bacteria. Recently, a new generation of hybrid nanozymes, such as Au nanoparticles-graphitic carbon nitride (Au/g-C₃N₄), graphene quantum dot–Ag nanoparticles (GQD/AgNP), has been constructed with synergistically improved catalytic efficiency for more outstanding bactericidal performance. Apart from medical applications, nanozymes also have been used in industrial area. V₂O₅ nanowires and CeO_2−x nanorods acting like natural haloperoxidase can prevent marine biofouling through catalyzing the oxidation of bromide ions with hydrogen peroxide to hypobromous acid, which interferes with the quorum sensing system of bacteria for thwarting biofilm development. Nanozymes are stable, biocompatible and not causing drug resistance, having great potential to be the substitution of conventional biocides.

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Vorheriges Kapitel Nanozymes for Therapeutics

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Titel: Nanozymes for Antimicrobes: Precision Biocide
verfasst von: Zhuobin Xu
Dandan Li
Zhiyue Qiu
Lizeng Gao
Verlag: Springer Singapore
Buch: Nanozymology
Print ISBN: 978-981-15-1489-0

Electronic ISBN: 978-981-15-1490-6

Copyright-Jahr: 2020
DOI: https://doi.org/10.1007/978-981-15-1490-6_15

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