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Erschienen in: Journal of Materials Science 19/2017

27.06.2017 | Chemical routes to materials

One-pot multicomponent click synthesis of pyrazole derivatives using cyclodextrin-supported capsaicin nanoparticles as catalyst

verfasst von: Priya Arora, Jaspreet Kaur Rajput

Erschienen in: Journal of Materials Science | Ausgabe 19/2017

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Abstract

Facile and efficient methodology for one-pot multicomponent click synthesis of pyrazole derivatives by using phenyl hydrazine, malononitrile and varying degrees of substituted aldehydes has been described. As a recyclable heterogeneous catalyst, we used CPS-CDMNPs. The nanoparticles were prepared by two-step synthesis using co-precipitation and ultrasonication method for the synthesis of CDMNPs, and further capsaicin was deposited on CDMNPs by wet impregnation method. The catalyst can be recovered in a facile manner from the reaction mixture magnetically by applying magnet outside the flask. Moreover, this protocol features the shortest reaction time, simple procedure, high conversion and no tedious workup procedures.

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Metadaten
Titel
One-pot multicomponent click synthesis of pyrazole derivatives using cyclodextrin-supported capsaicin nanoparticles as catalyst
verfasst von
Priya Arora
Jaspreet Kaur Rajput
Publikationsdatum
27.06.2017
Verlag
Springer US
Erschienen in
Journal of Materials Science / Ausgabe 19/2017
Print ISSN: 0022-2461
Elektronische ISSN: 1573-4803
DOI
https://doi.org/10.1007/s10853-017-1304-2

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