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Polymer Bulletin
Erschienen in: Polymer Bulletin 2/2020

23.04.2019 | Original Paper

Plasma-initiated polymerization of N-isopropylacrylamide and functionalized with dopamine for the adhesion to Hela cells

verfasst von: Xu Yang, Zhaojie Sun, Jingru Gao, Chunhui Yang, Dongyan Tang

Erschienen in: Polymer Bulletin | Ausgabe 2/2020

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Abstract

Temperature-responsive films of poly(N-isopropylacrylamide) (PNIPAM) were facilely fabricated by one-step plasma-initiated polymerization and then functionalized by self-polymerization of dopamine on the surface. High retention of the monomer structure and temperature-responsive properties in PNIPAM films were confirmed. After plasma-initiated polymerization, PNIPAM films formed protrusions and ridges surfaces. Moreover, cross-linker of N,N′-methylenebisacrylamide with different dosage was introduced into the systems to effectively modulate the roughness of PNIPAM films and to supply better adhesive surface. Furthermore, in cell culture, satisfactory survival rate of the attached Hela cells was obtained on PNIPAM films, and the cell viability was improved further on PNIPAM/PDA films. The results indicated that such films might be applicable in medical treatment and tissue engineering, due to their adjusted adhesion ability and less toxicity to cells.
Vorheriger Artikel The role of gold nanoparticles in the structural and electrical properties of Cs/PVP blend
Nächster Artikel Synthetic talc as catalyst and filler for waterborne polyurethane-based nanocomposite synthesis

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Metadaten
Titel
Plasma-initiated polymerization of N-isopropylacrylamide and functionalized with dopamine for the adhesion to Hela cells
verfasst von
Xu Yang
Zhaojie Sun
Jingru Gao
Chunhui Yang
Dongyan Tang
Publikationsdatum
23.04.2019
Verlag
Springer Berlin Heidelberg
Erschienen in
Polymer Bulletin / Ausgabe 2/2020
Print ISSN: 0170-0839
Elektronische ISSN: 1436-2449
DOI
https://doi.org/10.1007/s00289-019-02784-1

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