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Journal of Materials Science

Erschienen in:

01.07.2014

Preparation and physicochemical characteristics of cryogel based on gelatin and oxidised dextran

verfasst von: Dmitriy Berillo, Natalia Volkova

Erschienen in: Journal of Materials Science | Ausgabe 14/2014

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Abstract

In this study, a novel method of preparation of cryogels based on oxidised dextran (Ox.D) and gelatin (Gel) without sodium borohydride is proposed. The physico-chemical properties of obtained hydrogels were investigated. It was found that the stability of cryogels Ox.D–Gel is significantly depended on pH, and mechanical properties were improved after the freeze drying. The schemes of the reactions between Ox.D and Gel at different steps of the treatment of the material were suggested. According to ¹H-NMR data, the Amadori rearrangement occurred under the step of cryogelation. The increase of cross-linking degree through the formation of additional Schiff’s base group was observed as a result of incubation at high humidities or elevated temperature (60 °C). The obtained cryogels can be used as biocompatible and biodegradable scaffolds for proliferation of cells or other biomedical applications.

Vorheriger Artikel Preparation of electrospun nanofibers of star-shaped polycaprolactone and its blends with polyaniline

Nächster Artikel Kinetics of self-repair in inorganic glasses: modeling and experimental verification

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Titel: Preparation and physicochemical characteristics of cryogel based on gelatin and oxidised dextran
verfasst von: Dmitriy Berillo
Natalia Volkova
Publikationsdatum: 01.07.2014
Verlag: Springer US
Erschienen in: Journal of Materials Science / Ausgabe 14/2014
Print ISSN: 0022-2461
Elektronische ISSN: 1573-4803
DOI: https://doi.org/10.1007/s10853-014-8186-3

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