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Erschienen in: Journal of Materials Engineering and Performance 8/2016

14.06.2016

Production and Characterization of a Ag- and Zn-Doped Glass-Ceramic Material and In Vitro Evaluation of Its Biological Effects

verfasst von: Fatemeh Baghbani, Fathollah Moztarzadeh, Masoud Mozafari, Majid Raz, Hamideh Rezvani

Erschienen in: Journal of Materials Engineering and Performance | Ausgabe 8/2016

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Abstract

Bioactive glasses in the system SiO2-CaO-Na2O-P2O5-MgO with different amounts of zinc (Zn) and silver (Ag) were synthesized by the sol-gel technique and characterized. The bioactivity was studied during in vitro assays: the ability of hydroxycarbonate apatite (HCA) layer to form on the glass surface was examined after contact with simulated body fluid (SBF). The x-ray diffraction, Fourier transform infrared spectroscopy, scanning electron microscopy, and inductively coupled plasma atomic emission spectrometry (ICP) studies were performed after immersion in vitro assays. Also, the antibacterial and antifungal activities of glass samples against Pseudomonas aeruginosa (ATCC 27853), E. coli (ATCC 25922), and Candida albicans were measured by the halo zone test. Introduction of zinc and silver as the trace elements induces several modifications on the observed phenomena at the glass surface and in SBF solution after immersion of the samples. The chemical durability of the glasses, the formation of the silica-rich layer, and the crystallization of the HCA layer were affected. Samples with the higher content of zinc and silver exhibited an excellent antibacterial/antifungal activity.

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Metadaten
Titel
Production and Characterization of a Ag- and Zn-Doped Glass-Ceramic Material and In Vitro Evaluation of Its Biological Effects
verfasst von
Fatemeh Baghbani
Fathollah Moztarzadeh
Masoud Mozafari
Majid Raz
Hamideh Rezvani
Publikationsdatum
14.06.2016
Verlag
Springer US
Erschienen in
Journal of Materials Engineering and Performance / Ausgabe 8/2016
Print ISSN: 1059-9495
Elektronische ISSN: 1544-1024
DOI
https://doi.org/10.1007/s11665-016-2156-7

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