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Erschienen in:
1990 | OriginalPaper | Buchkapitel
Radiation and the Cell Cycle
verfasst von : Professor Dr. Jürgen Kiefer
Erschienen in: Biological Radiation Effects
Verlag: Springer Berlin Heidelberg
Enthalten in: Professional Book Archive
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Radiation sensitivity (expressed as loss of colony forming ability or mutability) depends on the cell cycle stage in which the cells are exposed. This is found both with UV and with sparsely ionizing radiations; in many cases, the two types show a mirror-image-like relationship. Radiation also slows down the progression of cells through the cycle; this effect is reversible with low doses. The inhibition of DNA synthesis is particularly relevant in this respect and will, therefore, be discussed in more detail.