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Polymer Bulletin

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01.12.2013 | Original Paper

Radiation synthesis, characterisation and antimicrobial application of novel copolymeric silver/poly(2-hydroxyethyl methacrylate/itaconic acid) nanocomposite hydrogels

verfasst von: M. Micic, T. Vukasinovic Milic, M. Mitric, B. Jokic, E. Suljovrujic

Erschienen in: Polymer Bulletin | Ausgabe 12/2013

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Abstract

Silver nanoparticles were fabricated via in situ reduction of silver nitrate embedded in swollen P(HEMA/IA) hydrogel, using gamma radiolysis method. Copolymeric hydrogels based on 2-hydroxyethyl methacrylate (HEMA) and itaconic acid (IA), previously synthesised by gamma radiation for wound dressing application, were used as a carrier and a stabilising agent, while ethyl alcohol was used as a free radical scavenger. The influence of different P(HEMA/IA) hydrogels and silver salt concentrations on the size and distribution of nanoparticles was investigated. The Ag/P(HEMA/IA) nanocomposites were characterised by high resolution scanning electron microscopy, energy dispersive spectroscopy, wide-angle X-ray diffraction, UV-Vis spectroscopy and swelling measurements. Escherichia coli (Gram-negative bacterium), Staphylococcus aureus (Gram-positive bacterium) and Candida albicans (fungus) were used to prove the antimicrobial properties of Ag/P(HEMA/IA) nanocomposites. The inhibition kinetics of bacteria growth was investigated by measuring the colony-forming unit. The antimicrobial effectiveness of the Ag/P(HEMA/IA) hydrogel nanocomposite was demonstrated even at small silver concentrations. P(HEMA/IA) hydrogels containing nanosilver particles was found suitable to be used as wound dressing.

Vorheriger Artikel Preparation and properties of partially hydrolyzed cross-linked guar gum

Nächster Artikel l-Lysine-derived optically active poly(hydrazide-imide)s: synthesis, characterization and their application in removal of heavy metal ions

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Titel: Radiation synthesis, characterisation and antimicrobial application of novel copolymeric silver/poly(2-hydroxyethyl methacrylate/itaconic acid) nanocomposite hydrogels
verfasst von: M. Micic
T. Vukasinovic Milic
M. Mitric
B. Jokic
E. Suljovrujic
Publikationsdatum: 01.12.2013
Verlag: Springer Berlin Heidelberg
Erschienen in: Polymer Bulletin / Ausgabe 12/2013
Print ISSN: 0170-0839
Elektronische ISSN: 1436-2449
DOI: https://doi.org/10.1007/s00289-013-1026-9

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