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Journal of Nanoparticle Research
Erschienen in: Journal of Nanoparticle Research 11/2013

01.11.2013 | Research Paper

Starch-modified magnetite nanoparticles for impregnation into cartilage

verfasst von: Yulia M. Soshnikova, Svetlana G. Roman, Natalia A. Chebotareva, Olga I. Baum, Mariya V. Obrezkova, Richard B. Gillis, Stephen E. Harding, Emil N. Sobol, Valeriy V. Lunin

Erschienen in: Journal of Nanoparticle Research | Ausgabe 11/2013

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Abstract

The paper presents preparation and characterization of starch-modified Fe3O4 nanoparticles (NPs) in aqueous dispersion after impregnation into healthy and damaged types of cartilage. We show that starch-modified dispersion has a narrower size distribution than a non‐stabilized one. The average hydrodynamic radius of magnetite NPs in a dispersion used for impregnation into cartilage is (48 ± 1) nm with the width of the distribution from 5 to 200 nm. We investigate stability of aqueous magnetite NPs dispersions during storage and with increase in temperature (up to 70 °C). We find that polydisperse magnetite NPs can penetrate into cartilage and the size and concentration of impregnated particles depend on the organization of the tissue structure. The results confirm the possibility of application of magnetite NPs in diagnostics and laser treatment of degenerative cartilage deceases.
Vorheriger Artikel Preparation and characterization of silica–gold core–shell nanoparticles
Nächster Artikel Field-dependent motion of bio-functionalized magnetic nanoparticle clusters under a rotating magnetic field

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Metadaten
Titel
Starch-modified magnetite nanoparticles for impregnation into cartilage
verfasst von
Yulia M. Soshnikova
Svetlana G. Roman
Natalia A. Chebotareva
Olga I. Baum
Mariya V. Obrezkova
Richard B. Gillis
Stephen E. Harding
Emil N. Sobol
Valeriy V. Lunin
Publikationsdatum
01.11.2013
Verlag
Springer Netherlands
Erschienen in
Journal of Nanoparticle Research / Ausgabe 11/2013
Print ISSN: 1388-0764
Elektronische ISSN: 1572-896X
DOI
https://doi.org/10.1007/s11051-013-2092-5

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