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2024 | OriginalPaper | Buchkapitel

2. Strategies for Quality Control of Polysaccharides in Chinese Medicines

verfasst von : Shaoping Li, Jing Zhao, Chiwai Ip

Erschienen in: Quality Control of Chinese Medicines

Verlag: Springer Nature Singapore

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Abstract

Polysaccharides with multiple biological activities are usually considered as one of the major bioactive compounds in Chinese medicines (CMs). At present, the development of drugs and functional foods related to polysaccharides has attracted a great deal of attention due to their great potential effects and diverse action mechanisms. However, quality control of polysaccharides is the bottleneck and challenge due to their complexity and chemical diversity. Actually, the bioactivities of polysaccharides are closely related to their molecular structures. In order to ensure their safety and efficacy, the development of novel approaches based on the molecular structures for the improvement of quality control of polysaccharides is significantly important. Therefore, in this article, the relationship between biological activities and chemical structures, as well as the action mechanisms of polysaccharides from CMs were summarized first. Furthermore, saccharide mapping, a novel strategy for quality control of bioactive polysaccharides from CMs, was introduced and the application and perspectives were also discussed.

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Literatur
1.
Zurück zum Zitat S.P. Li, D.T. Wu, G.P. Lv, J. Zhao, Carbohydrates analysis in herbal glycomics. Trends Analyt. Chem. 52, 155–169 (2013)CrossRef S.P. Li, D.T. Wu, G.P. Lv, J. Zhao, Carbohydrates analysis in herbal glycomics. Trends Analyt. Chem. 52, 155–169 (2013)CrossRef
2.
Zurück zum Zitat D.J. Hu, K.L. Cheong, J. Zhao, S.P. Li, Chromatography in characterization of polysaccharides from medicinal plants and fungi. J. Sep. Sci. 36, 1–19 (2013)PubMedCrossRef D.J. Hu, K.L. Cheong, J. Zhao, S.P. Li, Chromatography in characterization of polysaccharides from medicinal plants and fungi. J. Sep. Sci. 36, 1–19 (2013)PubMedCrossRef
3.
Zurück zum Zitat X. Zhao, B.F. Li, C.H. Xue, L.P. Sun, Effect of molecular weight on the antioxidant property of low molecular weight alginate from Laminaria japonica. J. Appl. Phycol. 24, 295–300 (2012)CrossRef X. Zhao, B.F. Li, C.H. Xue, L.P. Sun, Effect of molecular weight on the antioxidant property of low molecular weight alginate from Laminaria japonica. J. Appl. Phycol. 24, 295–300 (2012)CrossRef
4.
Zurück zum Zitat L.Q. Sun, C. Wang, Q.J. Shi, C.H. Ma, Preparation of different molecular weight polysaccharides from Porphyridium cruentum and their antioxidant activities. Int. J. Biol. Macromol. 45, 42–47 (2009)CrossRef L.Q. Sun, C. Wang, Q.J. Shi, C.H. Ma, Preparation of different molecular weight polysaccharides from Porphyridium cruentum and their antioxidant activities. Int. J. Biol. Macromol. 45, 42–47 (2009)CrossRef
5.
Zurück zum Zitat H.J. Zhang, W.J. Mao, F. Fang, H.Y. Li, H.H. Sun, Y. Chen, X.H. Qi, Chemical characteristics and anticoagulant activities of a sulfated polysaccharide and its fragments from Monostroma latissimum. Carbohydr. Polym. 71, 428–434 (2008)CrossRef H.J. Zhang, W.J. Mao, F. Fang, H.Y. Li, H.H. Sun, Y. Chen, X.H. Qi, Chemical characteristics and anticoagulant activities of a sulfated polysaccharide and its fragments from Monostroma latissimum. Carbohydr. Polym. 71, 428–434 (2008)CrossRef
6.
Zurück zum Zitat C.M. Yang, Y.J. Zhou, R.J. Wang, M.L. Hu, Anti-angiogenic effects and mechanisms of polysaccharides from Antrodia cinnamomea with different molecular weights. J. Ethnopharmacol. 123, 407–412 (2009)CrossRef C.M. Yang, Y.J. Zhou, R.J. Wang, M.L. Hu, Anti-angiogenic effects and mechanisms of polysaccharides from Antrodia cinnamomea with different molecular weights. J. Ethnopharmacol. 123, 407–412 (2009)CrossRef
7.
Zurück zum Zitat Y.Y. Zhang, S. Li, X.H. Wang, L.N. Zhang, P.C.K. Cheung, Advances in lentinan: Isolation, structure, chain conformation and bioactivities. Food Hydrocoll. 25, 196–206 (2011)CrossRef Y.Y. Zhang, S. Li, X.H. Wang, L.N. Zhang, P.C.K. Cheung, Advances in lentinan: Isolation, structure, chain conformation and bioactivities. Food Hydrocoll. 25, 196–206 (2011)CrossRef
8.
Zurück zum Zitat R. Russell, M. Paterson, Ganoderma - A therapeutic fungal biofactory. Phytochemistry 67, 1985–2001 (2006)CrossRef R. Russell, M. Paterson, Ganoderma - A therapeutic fungal biofactory. Phytochemistry 67, 1985–2001 (2006)CrossRef
9.
Zurück zum Zitat S. Nie, H. Zhang, W. Li, M. Xie, Current development of polysaccharides from Ganoderma: Isolation, structure and bioactivities. Bioact Carbohydr Diet Fibre. 1, 10–20 (2013)CrossRef S. Nie, H. Zhang, W. Li, M. Xie, Current development of polysaccharides from Ganoderma: Isolation, structure and bioactivities. Bioact Carbohydr Diet Fibre. 1, 10–20 (2013)CrossRef
10.
Zurück zum Zitat Q. Luo, Y.Z. Cai, J. Yan, M. Sun, H. Corke, Hypoglycemic and hypolipidemic effects and antioxidant activity of fruit extracts from Lycium barbarum. Life Sci. 76, 137–149 (2004)PubMedCrossRef Q. Luo, Y.Z. Cai, J. Yan, M. Sun, H. Corke, Hypoglycemic and hypolipidemic effects and antioxidant activity of fruit extracts from Lycium barbarum. Life Sci. 76, 137–149 (2004)PubMedCrossRef
11.
Zurück zum Zitat L. Gan, S.H. Zhang, X.L. Yang, H.B. Xu, Immunomodulation and antitumor activity by a polysaccharide-protein complex from Lycium barbarum. Int. Immunopharmacol. 4, 563–569 (2004)CrossRef L. Gan, S.H. Zhang, X.L. Yang, H.B. Xu, Immunomodulation and antitumor activity by a polysaccharide-protein complex from Lycium barbarum. Int. Immunopharmacol. 4, 563–569 (2004)CrossRef
12.
Zurück zum Zitat R.J. Redgwell, D. Curti, J.K. Wang, J.M. Dobruchowska, G.J. Gerwig, J.P. Kamerling, P. Bucheli, Cell wall polysaccharides of Chinese Wolfberry (Lycium barbarum): Part 2. Characterisation of arabinogalactan-proteins. Carbohydr. Polym. 84, 1075–1083 (2011)CrossRef R.J. Redgwell, D. Curti, J.K. Wang, J.M. Dobruchowska, G.J. Gerwig, J.P. Kamerling, P. Bucheli, Cell wall polysaccharides of Chinese Wolfberry (Lycium barbarum): Part 2. Characterisation of arabinogalactan-proteins. Carbohydr. Polym. 84, 1075–1083 (2011)CrossRef
13.
Zurück zum Zitat H. Amagase, N.R. Farnsworth, A review of botanical characteristics, phytochemistry, clinical relevance in efficacy and safety of Lycium barbarum fruit (Goji). Food Res. Int. 44, 1702–1717 (2011)CrossRef H. Amagase, N.R. Farnsworth, A review of botanical characteristics, phytochemistry, clinical relevance in efficacy and safety of Lycium barbarum fruit (Goji). Food Res. Int. 44, 1702–1717 (2011)CrossRef
14.
Zurück zum Zitat P.C. Lin, D.T. Wu, J. Xie, J. Zhao, S.P. Li, Characterization and comparison of bioactive polysaccharides from the tubers of Gymnadenia conopsea. Food Hydrocoll. 43, 199–206 (2015)CrossRef P.C. Lin, D.T. Wu, J. Xie, J. Zhao, S.P. Li, Characterization and comparison of bioactive polysaccharides from the tubers of Gymnadenia conopsea. Food Hydrocoll. 43, 199–206 (2015)CrossRef
15.
Zurück zum Zitat Y.Y. Wang, K.H. Khoo, S.T. Chen, C.C. Lin, C.H. Wong, C.H. Lin, Studies on the immuno-modulating and antitumor activities of Ganoderma lucidum (Reishi) polysaccharides: Functional and proteomic analyses of a fucose-containing glycoprotein fraction responsible for the activities. Bioorg. Med. Chem. 10, 1057–1062 (2002)CrossRef Y.Y. Wang, K.H. Khoo, S.T. Chen, C.C. Lin, C.H. Wong, C.H. Lin, Studies on the immuno-modulating and antitumor activities of Ganoderma lucidum (Reishi) polysaccharides: Functional and proteomic analyses of a fucose-containing glycoprotein fraction responsible for the activities. Bioorg. Med. Chem. 10, 1057–1062 (2002)CrossRef
16.
Zurück zum Zitat S.F. Liao, C.H. Liang, M.Y. Ho, T.L. Hsu, T.I. Tsai, Y.S.Y. Hsieh, C.M. Tsai, S.T. Li, Y.Y. Cheng, S.M. Tsao, T.Y. Lin, Z.Y. Lin, W.B. Yang, C.T. Ren, K.I. Lin, K.H. Khoo, C.H. Lin, H.Y. Hsu, C.Y. Wu, C.H. Wong, Immunization of fucose-containing polysaccharides from Reishi mushroom induces antibodies to tumor-associated Globo H-series epitopes. Proc. Natl. Acad. Sci. U.S.A. 110, 13809–13814 (2013)PubMedPubMedCentralCrossRef S.F. Liao, C.H. Liang, M.Y. Ho, T.L. Hsu, T.I. Tsai, Y.S.Y. Hsieh, C.M. Tsai, S.T. Li, Y.Y. Cheng, S.M. Tsao, T.Y. Lin, Z.Y. Lin, W.B. Yang, C.T. Ren, K.I. Lin, K.H. Khoo, C.H. Lin, H.Y. Hsu, C.Y. Wu, C.H. Wong, Immunization of fucose-containing polysaccharides from Reishi mushroom induces antibodies to tumor-associated Globo H-series epitopes. Proc. Natl. Acad. Sci. U.S.A. 110, 13809–13814 (2013)PubMedPubMedCentralCrossRef
17.
Zurück zum Zitat L. Zhang, X.L. Li, X.J. Xu, F.B. Zeng, Correlation between antitumor activity, molecular weight, and conformation of lentinan. Carbohydr. Res. 340, 1515–1521 (2005)CrossRef L. Zhang, X.L. Li, X.J. Xu, F.B. Zeng, Correlation between antitumor activity, molecular weight, and conformation of lentinan. Carbohydr. Res. 340, 1515–1521 (2005)CrossRef
18.
Zurück zum Zitat S.S. Li, Y.P. Jin, C.L. Yao, Y.P. Wang, Research achievements on structures and activities of polysaccharides from Panax ginseng. China J Chin Mater Med. 39, 4709–4715 (2014) S.S. Li, Y.P. Jin, C.L. Yao, Y.P. Wang, Research achievements on structures and activities of polysaccharides from Panax ginseng. China J Chin Mater Med. 39, 4709–4715 (2014)
19.
Zurück zum Zitat Y.X. Sun, Structure and biological activities of the polysaccharides from the leaves, roots and fruits of Panax ginseng CA Meyer: An overview. Carbohydr. Polym. 85, 490–499 (2011)CrossRef Y.X. Sun, Structure and biological activities of the polysaccharides from the leaves, roots and fruits of Panax ginseng CA Meyer: An overview. Carbohydr. Polym. 85, 490–499 (2011)CrossRef
20.
Zurück zum Zitat X.N. Yu, B. Cui, G.X. Ren, Progress in research on polysaccharides from American ginseng. Food Sci. 35, 301–305 (2014) X.N. Yu, B. Cui, G.X. Ren, Progress in research on polysaccharides from American ginseng. Food Sci. 35, 301–305 (2014)
21.
Zurück zum Zitat L.J. Wang, X.N. Yu, X.S. Yang, Y. Li, Y. Yao, E.M.K. Lui, G.X. Ren, Structural and anti-inflammatory characterization of a novel neutral polysaccharide from North American ginseng (Panax quinquefolius). Int. J. Biol. Macromol. 74, 12–17 (2015)CrossRef L.J. Wang, X.N. Yu, X.S. Yang, Y. Li, Y. Yao, E.M.K. Lui, G.X. Ren, Structural and anti-inflammatory characterization of a novel neutral polysaccharide from North American ginseng (Panax quinquefolius). Int. J. Biol. Macromol. 74, 12–17 (2015)CrossRef
22.
Zurück zum Zitat M.L. Jin, K. Zhao, Q.S. Huang, C.L. Xu, P. Shang, Isolation, structure and bioactivities of the polysaccharides from Angelica sinensis (Oliv.) Diels: A review. Carbohydr. Polym. 89, 713–722 (2012) M.L. Jin, K. Zhao, Q.S. Huang, C.L. Xu, P. Shang, Isolation, structure and bioactivities of the polysaccharides from Angelica sinensis (Oliv.) Diels: A review. Carbohydr. Polym. 89, 713–722 (2012)
23.
Zurück zum Zitat M. Jin, Q. Huang, K. Zhao, P. Shang, Biological activities and potential health benefit effects of polysaccharides isolated from Lycium barbarum L. Int. J. Biol. Macromol. 54, 16–23 (2013)CrossRef M. Jin, Q. Huang, K. Zhao, P. Shang, Biological activities and potential health benefit effects of polysaccharides isolated from Lycium barbarum L. Int. J. Biol. Macromol. 54, 16–23 (2013)CrossRef
24.
Zurück zum Zitat H.Y. Wang, M. Li, Advances on pharmacological activities of polysaccharides from Dendrobium species. Global Tradit. Chin. Med. 7, 817–820 (2014) H.Y. Wang, M. Li, Advances on pharmacological activities of polysaccharides from Dendrobium species. Global Tradit. Chin. Med. 7, 817–820 (2014)
25.
Zurück zum Zitat X. Xing, S.W. Cui, S. Nie, G.O. Phillips, H. Douglas Goff, Q. Wang, A review of isolation process, structural characteristics, and bioactivities of water-soluble polysaccharides from Dendrobium plants. Bioact. Carbohydr. Diet Fibre. 1, 131–147 (2013)CrossRef X. Xing, S.W. Cui, S. Nie, G.O. Phillips, H. Douglas Goff, Q. Wang, A review of isolation process, structural characteristics, and bioactivities of water-soluble polysaccharides from Dendrobium plants. Bioact. Carbohydr. Diet Fibre. 1, 131–147 (2013)CrossRef
26.
Zurück zum Zitat C.L. Jiang, C. Tang, Y. Qiang, H.Y. Suo, L. Li, Immunoregulation Effect of Astragalus Polysaccharides. Food Sci. 34, 327–332 (2013) C.L. Jiang, C. Tang, Y. Qiang, H.Y. Suo, L. Li, Immunoregulation Effect of Astragalus Polysaccharides. Food Sci. 34, 327–332 (2013)
27.
Zurück zum Zitat M. Jin, K. Zhao, Q. Huang, P. Shang, Structural features and biological activities of the polysaccharides from Astragalus membranaceus. Int. J. Biol. Macromol. 64, 257–266 (2014)CrossRef M. Jin, K. Zhao, Q. Huang, P. Shang, Structural features and biological activities of the polysaccharides from Astragalus membranaceus. Int. J. Biol. Macromol. 64, 257–266 (2014)CrossRef
28.
Zurück zum Zitat X.L. Chang, B.Y. Chen, Y.M. Feng, Water-soluble polysaccharides isolated from skin juice, gel juice and flower of Aloe vera Miller. J. Taiwan Inst. Chem. Eng. 42, 197–203 (2011)CrossRef X.L. Chang, B.Y. Chen, Y.M. Feng, Water-soluble polysaccharides isolated from skin juice, gel juice and flower of Aloe vera Miller. J. Taiwan Inst. Chem. Eng. 42, 197–203 (2011)CrossRef
29.
Zurück zum Zitat G.D. Sierra-Garcia, R. Castro-Rios, A. Gonzalez-Horta, J. Lara-Arias, A. Chavez-Montes, Acemannan, an extracted polysaccharide from Aloe vera: A literature review. Nat. Prod. Commun. 9, 1217–1221 (2014) G.D. Sierra-Garcia, R. Castro-Rios, A. Gonzalez-Horta, J. Lara-Arias, A. Chavez-Montes, Acemannan, an extracted polysaccharide from Aloe vera: A literature review. Nat. Prod. Commun. 9, 1217–1221 (2014)
30.
Zurück zum Zitat T.D. Li, Y. Luo, J.G. Li, Research Progress on Biological Activity of Aloe vera L Polysaccharide. J. Anhui Agric. Sci. 37, 2033–2035 (2009) T.D. Li, Y. Luo, J.G. Li, Research Progress on Biological Activity of Aloe vera L Polysaccharide. J. Anhui Agric. Sci. 37, 2033–2035 (2009)
31.
Zurück zum Zitat X.Y. Wu, G.H. Mao, T. Zhao, J.L. Zhao, F. Li, L.H. Liang, L.Q. Yang, Isolation, purification and in vitro anti-tumor activity of polysaccharide from Ginkgo biloba sarcotesta. Carbohydr. Polym. 86, 1073–1076 (2011)CrossRef X.Y. Wu, G.H. Mao, T. Zhao, J.L. Zhao, F. Li, L.H. Liang, L.Q. Yang, Isolation, purification and in vitro anti-tumor activity of polysaccharide from Ginkgo biloba sarcotesta. Carbohydr. Polym. 86, 1073–1076 (2011)CrossRef
32.
Zurück zum Zitat J.F. Yang, D.Y. Zhou, Z.Y. Liang, A new polysaccharide from leaf of Ginkgo biloba L. Fitoterapia 80, 43–47 (2009)PubMedCrossRef J.F. Yang, D.Y. Zhou, Z.Y. Liang, A new polysaccharide from leaf of Ginkgo biloba L. Fitoterapia 80, 43–47 (2009)PubMedCrossRef
33.
Zurück zum Zitat L.Q. Yang, Z.Q. Xu, X.Y. Wu, Q. Liu, J. Chen, J. Liu, Research Progress on Polysaccharides from Ginkgo biloba L. Food Sci. 25, 372–375 (2004) L.Q. Yang, Z.Q. Xu, X.Y. Wu, Q. Liu, J. Chen, J. Liu, Research Progress on Polysaccharides from Ginkgo biloba L. Food Sci. 25, 372–375 (2004)
34.
Zurück zum Zitat C.J. Shi, Y.D. Zhou, J.B. Zhang, G. Tian, Researches of polysaccharides from Achyrnthes bidentata. Chin. J. New Drugs 15, 1330–1334 (2006) C.J. Shi, Y.D. Zhou, J.B. Zhang, G. Tian, Researches of polysaccharides from Achyrnthes bidentata. Chin. J. New Drugs 15, 1330–1334 (2006)
35.
Zurück zum Zitat C. Wang, D. Hua, C. Yan, Structural characterization and antioxidant activities of a novel fructan from Achyranthes bidentata Blume, a famous medicinal plant in China. Ind. Crops Prod. 70, 427–434 (2015)CrossRef C. Wang, D. Hua, C. Yan, Structural characterization and antioxidant activities of a novel fructan from Achyranthes bidentata Blume, a famous medicinal plant in China. Ind. Crops Prod. 70, 427–434 (2015)CrossRef
36.
Zurück zum Zitat J. Zhao, J. Xie, L.Y. Wang, S.P. Li, Advanced development in chemical analysis of Cordyceps. J. Pharm. Biomed. Anal. 87, 271–289 (2014)PubMedCrossRef J. Zhao, J. Xie, L.Y. Wang, S.P. Li, Advanced development in chemical analysis of Cordyceps. J. Pharm. Biomed. Anal. 87, 271–289 (2014)PubMedCrossRef
37.
Zurück zum Zitat J.K. Yan, W.Q. Wang, J.Y. Wu, Recent advances in Cordyceps sinensis polysaccharides: Mycelial fermentation, isolation, structure, and bioactivities: A review. J. Funct. Foods 6, 33–47 (2014)PubMedCrossRef J.K. Yan, W.Q. Wang, J.Y. Wu, Recent advances in Cordyceps sinensis polysaccharides: Mycelial fermentation, isolation, structure, and bioactivities: A review. J. Funct. Foods 6, 33–47 (2014)PubMedCrossRef
38.
Zurück zum Zitat Z.T. Xu, X.U. Chen, Z.F. Zhong, L.D. Chen, Y.T. Wang, Ganoderma lucidum polysaccharides: Immunomodulation and potential anti-tumor activities. Am. J. Chin. Med. 39, 15–27 (2011)PubMedCrossRef Z.T. Xu, X.U. Chen, Z.F. Zhong, L.D. Chen, Y.T. Wang, Ganoderma lucidum polysaccharides: Immunomodulation and potential anti-tumor activities. Am. J. Chin. Med. 39, 15–27 (2011)PubMedCrossRef
39.
Zurück zum Zitat T. Cui, Y. Chisti, Polysaccharopeptides of Coriolus versicolor: Physiological activity, uses, and production. Biotechnol. Adv. 21, 109–122 (2003)CrossRef T. Cui, Y. Chisti, Polysaccharopeptides of Coriolus versicolor: Physiological activity, uses, and production. Biotechnol. Adv. 21, 109–122 (2003)CrossRef
40.
Zurück zum Zitat F.F. Wang, L.M. Hao, S.R. Jia, Q. Chen, S. Niu, Review on Polysaccharide from Coriolus versicolor. Food Ferment. Ind. 38, 148–151 (2012) F.F. Wang, L.M. Hao, S.R. Jia, Q. Chen, S. Niu, Review on Polysaccharide from Coriolus versicolor. Food Ferment. Ind. 38, 148–151 (2012)
41.
Zurück zum Zitat Q.G. Zou, L. Zhu, W. Wang, B.R. Xiang, Research progress on Coriolus versicolor glycopeptides. Chin. Tradit. Pat. Med. 25, 578–580 (2003) Q.G. Zou, L. Zhu, W. Wang, B.R. Xiang, Research progress on Coriolus versicolor glycopeptides. Chin. Tradit. Pat. Med. 25, 578–580 (2003)
42.
Zurück zum Zitat G.Y. Lu, L.F. Fan, Z.F. Zhang, H.J. Pan, Development of research on lentinan. Acta Agric. Zhejiangensis 21, 183–188 (2009) G.Y. Lu, L.F. Fan, Z.F. Zhang, H.J. Pan, Development of research on lentinan. Acta Agric. Zhejiangensis 21, 183–188 (2009)
43.
Zurück zum Zitat D.H. Ngo, S.K. Kim, Sulfated polysaccharides as bioactive agents from marine algae. Int. J. Biol. Macromol. 62, 70–75 (2013)CrossRef D.H. Ngo, S.K. Kim, Sulfated polysaccharides as bioactive agents from marine algae. Int. J. Biol. Macromol. 62, 70–75 (2013)CrossRef
44.
Zurück zum Zitat K. Senthilkumar, P. Manivasagan, J. Venkatesan, S.K. Kim, Brown seaweed fucoidan: Biological activity and apoptosis, growth signaling mechanism in cancer. Int. J. Biol. Macromol. 60, 366–374 (2013)CrossRef K. Senthilkumar, P. Manivasagan, J. Venkatesan, S.K. Kim, Brown seaweed fucoidan: Biological activity and apoptosis, growth signaling mechanism in cancer. Int. J. Biol. Macromol. 60, 366–374 (2013)CrossRef
45.
Zurück zum Zitat L.C. Wang, X.Y. Wang, H. Wu, R. Liu, Overview on biological activities and molecular characteristics of sulfated polysaccharides from marine green algae in recent years. Mar. Drugs 12, 4984–5020 (2014)PubMedPubMedCentralCrossRef L.C. Wang, X.Y. Wang, H. Wu, R. Liu, Overview on biological activities and molecular characteristics of sulfated polysaccharides from marine green algae in recent years. Mar. Drugs 12, 4984–5020 (2014)PubMedPubMedCentralCrossRef
46.
Zurück zum Zitat G.C.F. Chan, W.K. Chan, D.M.Y. Sze, The effects of beta-glucan on human immune and cancer cells. J. Hematol. Oncol. 2, 25 (2009)CrossRef G.C.F. Chan, W.K. Chan, D.M.Y. Sze, The effects of beta-glucan on human immune and cancer cells. J. Hematol. Oncol. 2, 25 (2009)CrossRef
47.
Zurück zum Zitat B. Schwartz, Y. Hadar, Possible mechanisms of action of mushroom-derived glucans on inflammatory bowel disease and associated cancer. Ann. Transl. Med. 2, 19 (2014)PubMedPubMedCentral B. Schwartz, Y. Hadar, Possible mechanisms of action of mushroom-derived glucans on inflammatory bowel disease and associated cancer. Ann. Transl. Med. 2, 19 (2014)PubMedPubMedCentral
48.
Zurück zum Zitat H.L. Liu, L. Zhou, S.S. Shi, Y. Wang, X.Y. Ni, F. Xiao, S.C. Wang, P. Li, K. Ding, Oligosaccharide G19 inhibits U-87 MG human glioma cells growth in vitro and in vivo by targeting epidermal growth factor (EGF) and activating p53/p21 signaling. Glycobiology 24, 748–765 (2014)PubMedCrossRef H.L. Liu, L. Zhou, S.S. Shi, Y. Wang, X.Y. Ni, F. Xiao, S.C. Wang, P. Li, K. Ding, Oligosaccharide G19 inhibits U-87 MG human glioma cells growth in vitro and in vivo by targeting epidermal growth factor (EGF) and activating p53/p21 signaling. Glycobiology 24, 748–765 (2014)PubMedCrossRef
49.
Zurück zum Zitat H.J. Zhao, H.Y. Liu, Y. Chen, X.L. Xin, J. Li, Y.T. Hou, Z.H. Zhang, X.W. Zhang, C.Y. Me, M.Y. Geng, J. Ding, Oligomannurarate sulfate, a novel heparanase inhibitor simultaneously targeting basic fibroblast growth factor, combats tumor angiogenesis and metastasis. Cancer Res. 66, 8779–8787 (2006)PubMedCrossRef H.J. Zhao, H.Y. Liu, Y. Chen, X.L. Xin, J. Li, Y.T. Hou, Z.H. Zhang, X.W. Zhang, C.Y. Me, M.Y. Geng, J. Ding, Oligomannurarate sulfate, a novel heparanase inhibitor simultaneously targeting basic fibroblast growth factor, combats tumor angiogenesis and metastasis. Cancer Res. 66, 8779–8787 (2006)PubMedCrossRef
50.
Zurück zum Zitat H. Qiu, B. Yang, Z.C. Pei, Z. Zhang, K. Ding, WSS25 inhibits growth of xenografted hepatocellular cancer cells in nude mice by disrupting angiogenesis via blocking bone morphogenetic protein (BMP)/Smad/Id1 signaling. J. Biol. Chem. 285, 32638–32646 (2010)PubMedPubMedCentralCrossRef H. Qiu, B. Yang, Z.C. Pei, Z. Zhang, K. Ding, WSS25 inhibits growth of xenografted hepatocellular cancer cells in nude mice by disrupting angiogenesis via blocking bone morphogenetic protein (BMP)/Smad/Id1 signaling. J. Biol. Chem. 285, 32638–32646 (2010)PubMedPubMedCentralCrossRef
51.
Zurück zum Zitat F. Xiao, H. Qiu, L. Zhou, X.K. Shen, L.P. Yang, K. Ding, WSS25 inhibits Dicer, downregulating microRNA-210, which targets Ephrin-A3, to suppress human microvascular endothelial cell (HMEC-1) tube formation. Glycobiology 23, 524–535 (2013)PubMedCrossRef F. Xiao, H. Qiu, L. Zhou, X.K. Shen, L.P. Yang, K. Ding, WSS25 inhibits Dicer, downregulating microRNA-210, which targets Ephrin-A3, to suppress human microvascular endothelial cell (HMEC-1) tube formation. Glycobiology 23, 524–535 (2013)PubMedCrossRef
52.
Zurück zum Zitat F. Xiao, H. Qiu, H. Cui, X. Ni, J. Li, W. Liao, L. Lu, K. Ding, MicroRNA-885-3p inhibits the growth of HT-29 colon cancer cell xenografts by disrupting angiogenesis via targeting BMPR1A and blocking BMP/Smad/Id1 signaling. Oncogene 34, 1968–1978 (2015)PubMedCrossRef F. Xiao, H. Qiu, H. Cui, X. Ni, J. Li, W. Liao, L. Lu, K. Ding, MicroRNA-885-3p inhibits the growth of HT-29 colon cancer cell xenografts by disrupting angiogenesis via targeting BMPR1A and blocking BMP/Smad/Id1 signaling. Oncogene 34, 1968–1978 (2015)PubMedCrossRef
53.
Zurück zum Zitat X.K. Shen, J.P. Fang, X.F. Lv, Z.C. Pei, Y. Wang, S.S. Jiang, K. Ding, Heparin Impairs Angiogenesis through Inhibition of MicroRNA-10b. J. Biol. Chem. 286, 26616–26627 (2011)PubMedPubMedCentralCrossRef X.K. Shen, J.P. Fang, X.F. Lv, Z.C. Pei, Y. Wang, S.S. Jiang, K. Ding, Heparin Impairs Angiogenesis through Inhibition of MicroRNA-10b. J. Biol. Chem. 286, 26616–26627 (2011)PubMedPubMedCentralCrossRef
54.
Zurück zum Zitat A.B.C. Samuelsen, J. Schrezenmeir, S.H. Knutsen, Effects of orally administered yeast-derived beta-glucans: A review. Mol. Nutr. Food Res. 58, 183–193 (2014)CrossRef A.B.C. Samuelsen, J. Schrezenmeir, S.H. Knutsen, Effects of orally administered yeast-derived beta-glucans: A review. Mol. Nutr. Food Res. 58, 183–193 (2014)CrossRef
55.
Zurück zum Zitat F.Y. Avci, X.M. Li, M. Tsuji, D.L. Kasper, Carbohydrates and T cells: A sweet twosome. Semin. Immunol. 25, 146–151 (2013)CrossRef F.Y. Avci, X.M. Li, M. Tsuji, D.L. Kasper, Carbohydrates and T cells: A sweet twosome. Semin. Immunol. 25, 146–151 (2013)CrossRef
57.
Zurück zum Zitat N. Cerf-Bensussan, V. Gaboriau-Routhiau, The immune system and the gut microbiota: Friends or foes? Nat. Rev. Immunol. 10, 735–744 (2010)CrossRef N. Cerf-Bensussan, V. Gaboriau-Routhiau, The immune system and the gut microbiota: Friends or foes? Nat. Rev. Immunol. 10, 735–744 (2010)CrossRef
58.
59.
Zurück zum Zitat A.W. Paton, R. Morona, J.C. Paton, Designer probiotics for prevention of enteric infections. Nat. Rev. Microbiol. 4, 193–200 (2006)CrossRef A.W. Paton, R. Morona, J.C. Paton, Designer probiotics for prevention of enteric infections. Nat. Rev. Microbiol. 4, 193–200 (2006)CrossRef
60.
Zurück zum Zitat V. Tremaroli, F. Backhed, Functional interactions between the gut microbiota and host metabolism. Nature 489, 242–249 (2012)PubMedCrossRef V. Tremaroli, F. Backhed, Functional interactions between the gut microbiota and host metabolism. Nature 489, 242–249 (2012)PubMedCrossRef
61.
Zurück zum Zitat N.M. Koropatkin, E.A. Cameron, E.C. Martens, How glycan metabolism shapes the human gut microbiota. Nat. Rev. Immunol. 10, 323–335 (2012) N.M. Koropatkin, E.A. Cameron, E.C. Martens, How glycan metabolism shapes the human gut microbiota. Nat. Rev. Immunol. 10, 323–335 (2012)
62.
Zurück zum Zitat H.J. Flint, K.P. Scott, S.H. Duncan, P. Louis, E. Forano, Microbial degradation of complex carbohydrates in the gut. Gut. Microbes. 3, 289–306 (2012)PubMedPubMedCentralCrossRef H.J. Flint, K.P. Scott, S.H. Duncan, P. Louis, E. Forano, Microbial degradation of complex carbohydrates in the gut. Gut. Microbes. 3, 289–306 (2012)PubMedPubMedCentralCrossRef
63.
Zurück zum Zitat N. Kamada, S.U. Seo, G.Y. Chen, G. Nunez, Role of the gut microbiota in immunity and inflammatory disease. Nat. Rev. Immunol. 13, 321–335 (2013)CrossRef N. Kamada, S.U. Seo, G.Y. Chen, G. Nunez, Role of the gut microbiota in immunity and inflammatory disease. Nat. Rev. Immunol. 13, 321–335 (2013)CrossRef
64.
Zurück zum Zitat A.C. Weymouth-Wilson, The role of carbohydrates in biologically active natural products. Nat. Prod. Rep. 14, 99–110 (1997)PubMedCrossRef A.C. Weymouth-Wilson, The role of carbohydrates in biologically active natural products. Nat. Prod. Rep. 14, 99–110 (1997)PubMedCrossRef
65.
Zurück zum Zitat M. Veverka, T. Dubaj, J. Gallovic, V. Jorik, E. Veverkova, M. Micusik, P. Simon, Beta-glucan complexes with selected nutraceuticals: Synthesis, characterization, and stability. J Funct Foods. 8, 309–318 (2014)CrossRef M. Veverka, T. Dubaj, J. Gallovic, V. Jorik, E. Veverkova, M. Micusik, P. Simon, Beta-glucan complexes with selected nutraceuticals: Synthesis, characterization, and stability. J Funct Foods. 8, 309–318 (2014)CrossRef
66.
Zurück zum Zitat M. Numata, S. Shinkai, Supramolecular wrapping chemistry’ by helix-forming polysaccharides: a powerful strategy for generating diverse polymeric nano-architectures. Chem. Commun. 47, 1961–1975 (2011)CrossRef M. Numata, S. Shinkai, Supramolecular wrapping chemistry’ by helix-forming polysaccharides: a powerful strategy for generating diverse polymeric nano-architectures. Chem. Commun. 47, 1961–1975 (2011)CrossRef
67.
Zurück zum Zitat L.Q. Yang, L.M. Zhang, Chemical structural and chain conformational characterization of some bioactive polysaccharides isolated from natural sources. Carbohydr. Polym. 76, 349–361 (2009)CrossRef L.Q. Yang, L.M. Zhang, Chemical structural and chain conformational characterization of some bioactive polysaccharides isolated from natural sources. Carbohydr. Polym. 76, 349–361 (2009)CrossRef
68.
Zurück zum Zitat H.T. Hu, Y.X. Wang, Z. Juan, D. Jing, Product Analysis of Plantago asiatica L. polysaccharide by acid hydrolysis. Food Sci. 35, 60–64 (2014) H.T. Hu, Y.X. Wang, Z. Juan, D. Jing, Product Analysis of Plantago asiatica L. polysaccharide by acid hydrolysis. Food Sci. 35, 60–64 (2014)
69.
Zurück zum Zitat T. Liang, Q. Fu, H.X. Xin, F.B. Li, Y. Jin, X.M. Liang, Structural characterization of Astragalus polysaccharides using partial acid hydrolysis-hydrophilic interaction liquid chromatography-mass spectrometry. Chin. J. Chroma. 32, 1306–1312 (2014)CrossRef T. Liang, Q. Fu, H.X. Xin, F.B. Li, Y. Jin, X.M. Liang, Structural characterization of Astragalus polysaccharides using partial acid hydrolysis-hydrophilic interaction liquid chromatography-mass spectrometry. Chin. J. Chroma. 32, 1306–1312 (2014)CrossRef
70.
Zurück zum Zitat H.Z. Guo, F. Wu, W.Q. Zhang, F.L. Liu, Identification of traditional Chinese medicines by oligosaccharide electrophoresis analysis assisted with cluster analysis. Chin. J. Chroma. 31, 1001–1004 (2013)CrossRef H.Z. Guo, F. Wu, W.Q. Zhang, F.L. Liu, Identification of traditional Chinese medicines by oligosaccharide electrophoresis analysis assisted with cluster analysis. Chin. J. Chroma. 31, 1001–1004 (2013)CrossRef
71.
Zurück zum Zitat J.M. Francois, A simple method for quantitative determination of polysaccharides in fungal cell walls. Nat. Protoc.Protoc. 1, 2995–3000 (2006)CrossRef J.M. Francois, A simple method for quantitative determination of polysaccharides in fungal cell walls. Nat. Protoc.Protoc. 1, 2995–3000 (2006)CrossRef
72.
Zurück zum Zitat J.H. Zhao, H.X. Li, W.P. Xi, W. An, L.L. Niu, Y.L. Cao, H.F. Wang, Y.J. Wang, Y. Yin, Changes in sugars and organic acids in wolfberry (Lycium barbarum L.) fruit during development and maturation. Food Chem. 173, 718–724 (2015) J.H. Zhao, H.X. Li, W.P. Xi, W. An, L.L. Niu, Y.L. Cao, H.F. Wang, Y.J. Wang, Y. Yin, Changes in sugars and organic acids in wolfberry (Lycium barbarum L.) fruit during development and maturation. Food Chem. 173, 718–724 (2015)
73.
Zurück zum Zitat Z.Y. Guo, L. Han, M. Yang, L.M. Liu, W.Q. Zou, Discussion on the quantitative determination of polysaccharides in Chinese medicine. Chin. Tradit. Pat. Med. 36, 2172–2176 (2014) Z.Y. Guo, L. Han, M. Yang, L.M. Liu, W.Q. Zou, Discussion on the quantitative determination of polysaccharides in Chinese medicine. Chin. Tradit. Pat. Med. 36, 2172–2176 (2014)
74.
Zurück zum Zitat O. Dahlman, A. Jacobs, A. Liljenberg, A.I. Olsson, Analysis of carbohydrates in wood and pulps employing enzymatic hydrolysis and subsequent capillary zone electrophoresis. J. Chromatogr. AChromatogr. A 891, 157–174 (2000)CrossRef O. Dahlman, A. Jacobs, A. Liljenberg, A.I. Olsson, Analysis of carbohydrates in wood and pulps employing enzymatic hydrolysis and subsequent capillary zone electrophoresis. J. Chromatogr. AChromatogr. A 891, 157–174 (2000)CrossRef
75.
Zurück zum Zitat J. Guan, S.P. Li, Discrimination of polysaccharides from traditional Chinese medicines using saccharide mapping-Enzymatic digestion followed by chromatographic analysis. J. Pharm. Biomed. Anal. 51, 590–598 (2010)PubMedCrossRef J. Guan, S.P. Li, Discrimination of polysaccharides from traditional Chinese medicines using saccharide mapping-Enzymatic digestion followed by chromatographic analysis. J. Pharm. Biomed. Anal. 51, 590–598 (2010)PubMedCrossRef
76.
Zurück zum Zitat S.P. Li, G.J. Qualitative, quantitative analysis method for polyoses, Administration CNIP, (eds.), Li (China, Zhong Ping, 2009), pp.1–20 S.P. Li, G.J. Qualitative, quantitative analysis method for polyoses, Administration CNIP, (eds.), Li (China, Zhong Ping, 2009), pp.1–20
77.
Zurück zum Zitat K.L. Cheong, D.T. Wu, J. Zhao, S.P. Li, A rapid and accurate method for quantitative estimation of natural polysaccharides and their fractions using high performance size exclusion chromatography coupled with multi angle laser light scattering and refractive index detector. J. Chromatogr. A 1400, 98–106 (2015)CrossRef K.L. Cheong, D.T. Wu, J. Zhao, S.P. Li, A rapid and accurate method for quantitative estimation of natural polysaccharides and their fractions using high performance size exclusion chromatography coupled with multi angle laser light scattering and refractive index detector. J. Chromatogr. A 1400, 98–106 (2015)CrossRef
78.
Zurück zum Zitat D.T. Wu, J. Xie, L.Y. Wang, Y.J. Ju, G.P. Lv, F. Leong, J. Zhao, S.P. Li, Characterization of bioactive polysaccharides from Cordyceps militaris produced in China using saccharide mapping. J. Funct. Foods. 9, 315–323 (2014)CrossRef D.T. Wu, J. Xie, L.Y. Wang, Y.J. Ju, G.P. Lv, F. Leong, J. Zhao, S.P. Li, Characterization of bioactive polysaccharides from Cordyceps militaris produced in China using saccharide mapping. J. Funct. Foods. 9, 315–323 (2014)CrossRef
79.
Zurück zum Zitat D.T. Wu, W.Z. Li, J. Chen, Q.X. Zhong, Y.J. Ju, J. Zhao, A. Bzhelyansky, S.P. Li, An evaluation system for characterization of polysaccharides from the fruiting body of Hericium erinaceus and identification of its commercial product. Carbohydr. Polym. 124, 201–207 (2015)CrossRef D.T. Wu, W.Z. Li, J. Chen, Q.X. Zhong, Y.J. Ju, J. Zhao, A. Bzhelyansky, S.P. Li, An evaluation system for characterization of polysaccharides from the fruiting body of Hericium erinaceus and identification of its commercial product. Carbohydr. Polym. 124, 201–207 (2015)CrossRef
80.
Zurück zum Zitat D.T. Wu, Y.J. Ju, J.F. Lu, J. Zhao, S.P. Li, Characterization and comparison of polysaccharides from dictyophora indusiata using saccharide mapping. Food Sci. 35, 66–70 (2014) D.T. Wu, Y.J. Ju, J.F. Lu, J. Zhao, S.P. Li, Characterization and comparison of polysaccharides from dictyophora indusiata using saccharide mapping. Food Sci. 35, 66–70 (2014)
81.
Zurück zum Zitat D.T. Wu, K.L. Cheong, L.Y. Wang, G.P. Lv, Y.J. Ju, K. Feng, J. Zhao, S.P. Li, Characterization and discrimination of polysaccharides from different species of Cordyceps using saccharide mapping based on PACE and HPTLC. Carbohydr. Polym. 103, 100–109 (2014)CrossRef D.T. Wu, K.L. Cheong, L.Y. Wang, G.P. Lv, Y.J. Ju, K. Feng, J. Zhao, S.P. Li, Characterization and discrimination of polysaccharides from different species of Cordyceps using saccharide mapping based on PACE and HPTLC. Carbohydr. Polym. 103, 100–109 (2014)CrossRef
82.
Zurück zum Zitat K.L. Cheong, D.T. Wu, D.J. Hu, J. Zhao, K.Y. Cao, C.F. Qiao, B.X. Han, S.P. Li, Comparison and characterization of the glycome of Panax species by high-performance thin-layer chromatography. JPC-J. Planar. Chromat. 27, 449–453 (2014)CrossRef K.L. Cheong, D.T. Wu, D.J. Hu, J. Zhao, K.Y. Cao, C.F. Qiao, B.X. Han, S.P. Li, Comparison and characterization of the glycome of Panax species by high-performance thin-layer chromatography. JPC-J. Planar. Chromat. 27, 449–453 (2014)CrossRef
83.
Zurück zum Zitat D.T. Wu, J. Xie, D.J. Hu, J. Zhao, S.P. Li, Characterization of polysaccharides from Ganoderma spp. using saccharide mapping. Carbohydr. Polym. 97, 398–405 (2013) D.T. Wu, J. Xie, D.J. Hu, J. Zhao, S.P. Li, Characterization of polysaccharides from Ganoderma spp. using saccharide mapping. Carbohydr. Polym. 97, 398–405 (2013)
84.
Zurück zum Zitat Y.W. Chen, D.J. Hu, K.L. Cheong, J. Li, J. Xie, J. Zhao, S.P. Li, Quality evaluation of lentinan injection produced in China. J. Pharm. Biomed. Anal. 78–79, 176–182 (2013)PubMedCrossRef Y.W. Chen, D.J. Hu, K.L. Cheong, J. Li, J. Xie, J. Zhao, S.P. Li, Quality evaluation of lentinan injection produced in China. J. Pharm. Biomed. Anal. 78–79, 176–182 (2013)PubMedCrossRef
85.
Zurück zum Zitat J. Xie, J. Zhao, D.J. Hu, J.A. Duan, Y.P. Tang, S.P. Li, Comparison of polysaccharides from two species of Ganoderma. Molecules 17, 740–752 (2012)PubMedPubMedCentralCrossRef J. Xie, J. Zhao, D.J. Hu, J.A. Duan, Y.P. Tang, S.P. Li, Comparison of polysaccharides from two species of Ganoderma. Molecules 17, 740–752 (2012)PubMedPubMedCentralCrossRef
86.
Zurück zum Zitat J. Xu, J. Guan, X.J. Chen, J. Zhao, S.P. Li, Comparison of polysaccharides from different Dendrobium using saccharide mapping. J. Pharm. Biomed. Anal. 55, 977–983 (2011)PubMedCrossRef J. Xu, J. Guan, X.J. Chen, J. Zhao, S.P. Li, Comparison of polysaccharides from different Dendrobium using saccharide mapping. J. Pharm. Biomed. Anal. 55, 977–983 (2011)PubMedCrossRef
87.
Zurück zum Zitat J. Guan, J. Zhao, K. Feng, D.J. Hu, S.P. Li, Comparison and characterization of polysaccharides from natural and cultured Cordyceps using saccharide mapping. Anal. Bioanal. Chem. 399, 3465–3474 (2011)CrossRef J. Guan, J. Zhao, K. Feng, D.J. Hu, S.P. Li, Comparison and characterization of polysaccharides from natural and cultured Cordyceps using saccharide mapping. Anal. Bioanal. Chem. 399, 3465–3474 (2011)CrossRef
88.
Zurück zum Zitat G.E. Morlock, G. Sabir, Comparison of two orthogonal liquid chromatographic methods for quantitation of sugars in food. J. Liq. Chromatogr. Relat. Technol. 34, 902–919 (2011)CrossRef G.E. Morlock, G. Sabir, Comparison of two orthogonal liquid chromatographic methods for quantitation of sugars in food. J. Liq. Chromatogr. Relat. Technol. 34, 902–919 (2011)CrossRef
89.
Zurück zum Zitat F. Goubet, B. Morriswood, P. Dupree, Analysis of methylated and unmethylated polygalacturonic acid structure by polysaccharide analysis using carbohydrate gel electrophoresis. Anal. Biochem. 321, 174–182 (2003)CrossRef F. Goubet, B. Morriswood, P. Dupree, Analysis of methylated and unmethylated polygalacturonic acid structure by polysaccharide analysis using carbohydrate gel electrophoresis. Anal. Biochem. 321, 174–182 (2003)CrossRef
90.
Zurück zum Zitat D.T. Wu, K.L. Cheong, Y. Deng, P.C. Lin, F. Wei, X.J. Lv, Z.R. Long, J. Zhao, S.C. Ma, S.P. Li, Characterization and comparison of polysaccharides from Lycium barbarum in China using saccharide mapping based on PACE and HPTLC. Carbohydr Polym. (2015) D.T. Wu, K.L. Cheong, Y. Deng, P.C. Lin, F. Wei, X.J. Lv, Z.R. Long, J. Zhao, S.C. Ma, S.P. Li, Characterization and comparison of polysaccharides from Lycium barbarum in China using saccharide mapping based on PACE and HPTLC. Carbohydr Polym. (2015)
91.
Zurück zum Zitat J. Zhao, G.P. Lv, Y.W. Chen, S.P. Li, Advanced development in analysis of phytochemicals from medicine and food dual purposes plants used in China. J. Chromatogr. A 1218, 7453–7475 (2011)CrossRef J. Zhao, G.P. Lv, Y.W. Chen, S.P. Li, Advanced development in analysis of phytochemicals from medicine and food dual purposes plants used in China. J. Chromatogr. A 1218, 7453–7475 (2011)CrossRef
92.
Zurück zum Zitat J. Yang, Y.W. Chen, N.I. Leong, J. Zhao, J.A. Duan, Y.P. Tang, S.P. Li, Quality evaluation of different products derived from Ganoderma. J. Med. Plant. Res. 6, 1969–1974 (2012) J. Yang, Y.W. Chen, N.I. Leong, J. Zhao, J.A. Duan, Y.P. Tang, S.P. Li, Quality evaluation of different products derived from Ganoderma. J. Med. Plant. Res. 6, 1969–1974 (2012)
93.
Zurück zum Zitat T.M.C.C. Filisetticozzi, N.C. Carpita, Measurement of uronic-acids without Interference from Neutral Sugars. Anal. Biochem.Biochem. 197, 157–162 (1991)CrossRef T.M.C.C. Filisetticozzi, N.C. Carpita, Measurement of uronic-acids without Interference from Neutral Sugars. Anal. Biochem.Biochem. 197, 157–162 (1991)CrossRef
94.
Zurück zum Zitat J. Xu, S.L. Li, R.Q. Yue, C.H. Ko, J.M. Hu, J. Liu, H.M. Ho, T. Yi, Z.Z. Zhao, J. Zhou, P.C. Leung, H.B. Chen, Q.B. Han, A novel and rapid HPGPC-based strategy for quality control of saccharide-dominant herbal materials: Dendrobium officinale, a case study. Anal. Bioanal. Chem. 406, 6409–6417 (2014)CrossRef J. Xu, S.L. Li, R.Q. Yue, C.H. Ko, J.M. Hu, J. Liu, H.M. Ho, T. Yi, Z.Z. Zhao, J. Zhou, P.C. Leung, H.B. Chen, Q.B. Han, A novel and rapid HPGPC-based strategy for quality control of saccharide-dominant herbal materials: Dendrobium officinale, a case study. Anal. Bioanal. Chem. 406, 6409–6417 (2014)CrossRef
95.
Zurück zum Zitat L.E. Rasmussen, A.S. Meyer, Size exclusion chromatography for the quantitative profiling of the enzyme-catalyzed hydrolysis of xylo-oligosaccharides. J. Agric. Food Chem. 58, 762–769 (2010)PubMedCrossRef L.E. Rasmussen, A.S. Meyer, Size exclusion chromatography for the quantitative profiling of the enzyme-catalyzed hydrolysis of xylo-oligosaccharides. J. Agric. Food Chem. 58, 762–769 (2010)PubMedCrossRef
96.
Zurück zum Zitat E. Gomez-Ordonez, A. Jimenez-Escrig, P. Ruperez, Molecular weight distribution of polysaccharides from edible seaweeds by high-performance size-exclusion chromatography (HPSEC). Talanta 93, 153–159 (2012)PubMedCrossRef E. Gomez-Ordonez, A. Jimenez-Escrig, P. Ruperez, Molecular weight distribution of polysaccharides from edible seaweeds by high-performance size-exclusion chromatography (HPSEC). Talanta 93, 153–159 (2012)PubMedCrossRef
97.
Zurück zum Zitat L.Y. Wang, K.L. Cheong, D.T. Wu, L.Z. Meng, J. Zhao, S.P. Li, Fermentation optimization for the production of bioactive polysaccharides from Cordyceps sinensis fungus UM01. Int. J. Biol. Macromol. 79, 180–185 (2015)CrossRef L.Y. Wang, K.L. Cheong, D.T. Wu, L.Z. Meng, J. Zhao, S.P. Li, Fermentation optimization for the production of bioactive polysaccharides from Cordyceps sinensis fungus UM01. Int. J. Biol. Macromol. 79, 180–185 (2015)CrossRef
98.
Zurück zum Zitat Y. Deng, J. Zhao, S.P. Li, Quantitative estimation of enzymatic released specific oligosaccharides from Hericium erinaceus polysaccharides using CE-LIF. J. Pharm. Anal. 13, 201–208 (2023)PubMedCrossRef Y. Deng, J. Zhao, S.P. Li, Quantitative estimation of enzymatic released specific oligosaccharides from Hericium erinaceus polysaccharides using CE-LIF. J. Pharm. Anal. 13, 201–208 (2023)PubMedCrossRef
99.
Zurück zum Zitat Y. Deng, L.X. Chen, B.J. Zhu, J. Zhao, S.P. Li, A quantitative method for polysaccharides based on endo-enzymatic released specific oligosaccharides: A case of Lentinus edodes. Int. J. Biol. Macromol. 205, 15–22 (2022)CrossRef Y. Deng, L.X. Chen, B.J. Zhu, J. Zhao, S.P. Li, A quantitative method for polysaccharides based on endo-enzymatic released specific oligosaccharides: A case of Lentinus edodes. Int. J. Biol. Macromol. 205, 15–22 (2022)CrossRef
Metadaten
Titel
Strategies for Quality Control of Polysaccharides in Chinese Medicines
verfasst von
Shaoping Li
Jing Zhao
Chiwai Ip
Copyright-Jahr
2024
Verlag
Springer Nature Singapore
DOI
https://doi.org/10.1007/978-981-99-9871-5_2

    Marktübersichten

    Die im Laufe eines Jahres in der „adhäsion“ veröffentlichten Marktübersichten helfen Anwendern verschiedenster Branchen, sich einen gezielten Überblick über Lieferantenangebote zu verschaffen.