Skip to main content
Erschienen in: Journal of Nanoparticle Research 2/2014

01.02.2014 | Research Paper

Structural, stability, magnetic, and toxicity studies of nanocrystalline iron oxide and cobalt ferrites for biomedical applications

verfasst von: B. Peeples, V. Goornavar, C. Peeples, D. Spence, V. Parker, C. Bell, D. Biswal, G. T. Ramesh, A. K. Pradhan

Erschienen in: Journal of Nanoparticle Research | Ausgabe 2/2014

Einloggen

Aktivieren Sie unsere intelligente Suche, um passende Fachinhalte oder Patente zu finden.

search-config
loading …

Abstract

Iron oxide and cobalt ferrite magnetic nanoparticles (MNPs) of 5–15 nm range have been synthesized by the co-precipitation method, and the magnetic MNPs are functionalized by 3-aminopropyl triethoxy silane and citric acid. The crystalline quality of the MNPs was confirmed using X-ray diffraction, verifying the spinel structure. Spectroscopy study confirmed the presence of the corresponding functional groups on MNP surfaces and thermogravimetric analysis further confirmed functionalization. Coercivity and saturation magnetization exhibited superior superparamagnetic properties. Toxicity studies compared the dose dependent toxicity of both pure iron oxide and cobalt ferrite samples. The toxicity of surface functionalized MNPs showed the potential for use in biomedicine.

Sie haben noch keine Lizenz? Dann Informieren Sie sich jetzt über unsere Produkte:

Springer Professional "Wirtschaft+Technik"

Online-Abonnement

Mit Springer Professional "Wirtschaft+Technik" erhalten Sie Zugriff auf:

  • über 102.000 Bücher
  • über 537 Zeitschriften

aus folgenden Fachgebieten:

  • Automobil + Motoren
  • Bauwesen + Immobilien
  • Business IT + Informatik
  • Elektrotechnik + Elektronik
  • Energie + Nachhaltigkeit
  • Finance + Banking
  • Management + Führung
  • Marketing + Vertrieb
  • Maschinenbau + Werkstoffe
  • Versicherung + Risiko

Jetzt Wissensvorsprung sichern!

Springer Professional "Technik"

Online-Abonnement

Mit Springer Professional "Technik" erhalten Sie Zugriff auf:

  • über 67.000 Bücher
  • über 390 Zeitschriften

aus folgenden Fachgebieten:

  • Automobil + Motoren
  • Bauwesen + Immobilien
  • Business IT + Informatik
  • Elektrotechnik + Elektronik
  • Energie + Nachhaltigkeit
  • Maschinenbau + Werkstoffe




 

Jetzt Wissensvorsprung sichern!

Literatur
Zurück zum Zitat Amiri S, Shokrollahi H (2013) The role of cobalt ferrite magnetic nanoparticles in medical science. Mater Sci Eng 33:1–8CrossRef Amiri S, Shokrollahi H (2013) The role of cobalt ferrite magnetic nanoparticles in medical science. Mater Sci Eng 33:1–8CrossRef
Zurück zum Zitat Ayyappan S (2010) Influence of Co2+ ion concentration on the size, magnetic properties, and purity of CoFe2O4 spinel ferrite nanoparticles. J Phys Chem C 114:6334–6341CrossRef Ayyappan S (2010) Influence of Co2+ ion concentration on the size, magnetic properties, and purity of CoFe2O4 spinel ferrite nanoparticles. J Phys Chem C 114:6334–6341CrossRef
Zurück zum Zitat Habib AH, Ondeck CL, Chaudhary P, Bockstaller, McHenry ME (2008) Evaluation of iron-cobalt/ferrite core-shell nanoparticles for cancer thermotherapy. J Appl Phys 103:07A307-1CrossRef Habib AH, Ondeck CL, Chaudhary P, Bockstaller, McHenry ME (2008) Evaluation of iron-cobalt/ferrite core-shell nanoparticles for cancer thermotherapy. J Appl Phys 103:07A307-1CrossRef
Zurück zum Zitat Lee IL, Li PS, Yu WL, Shen HH (2012) Synthesis and interfacing of biocompatible iron oxide nanoparticles through the ferroxidase activity of Helicobacter pylori ferritin. Biofabrication 4:045001CrossRef Lee IL, Li PS, Yu WL, Shen HH (2012) Synthesis and interfacing of biocompatible iron oxide nanoparticles through the ferroxidase activity of Helicobacter pylori ferritin. Biofabrication 4:045001CrossRef
Zurück zum Zitat Manna P, Narang KK, Manna SK (2005) 1,2,4-Thiadiazolidine derivative inhibits nuclear transcription factor-κB and its dependent denes activation but induces apoptosis. Int J Cancer 113:549–560CrossRef Manna P, Narang KK, Manna SK (2005) 1,2,4-Thiadiazolidine derivative inhibits nuclear transcription factor-κB and its dependent denes activation but induces apoptosis. Int J Cancer 113:549–560CrossRef
Zurück zum Zitat Manna SK, Sarkar S, Barr J, Wise K, Barrera EV, Jejelowo O, Rice-Ficht AC, Ramesh GT (2007) Single-walled carbon nanotube induces oxidative stress and activates nuclear transcription factor-κB in human keratinocytes. Nano Lett 5:1676–1684CrossRef Manna SK, Sarkar S, Barr J, Wise K, Barrera EV, Jejelowo O, Rice-Ficht AC, Ramesh GT (2007) Single-walled carbon nanotube induces oxidative stress and activates nuclear transcription factor-κB in human keratinocytes. Nano Lett 5:1676–1684CrossRef
Zurück zum Zitat Sharma CS, Sarkar S, Periyakaruppan A, Barr J, Wise K, Thomas R, Wilson BL, Ramesh GT (2007) Single-walled carbon nanotubes induces oxidative stress in rat lung epithelial cells. J Nanosci Nanotechnol 7:2466–2472CrossRef Sharma CS, Sarkar S, Periyakaruppan A, Barr J, Wise K, Thomas R, Wilson BL, Ramesh GT (2007) Single-walled carbon nanotubes induces oxidative stress in rat lung epithelial cells. J Nanosci Nanotechnol 7:2466–2472CrossRef
Zurück zum Zitat Shen L, Laibinis PE, Hatton TA (1999) Bilayer surfactant stabilized magnetic fluids: synthesis and interactions at interface. Langmuir 15:447–453CrossRef Shen L, Laibinis PE, Hatton TA (1999) Bilayer surfactant stabilized magnetic fluids: synthesis and interactions at interface. Langmuir 15:447–453CrossRef
Zurück zum Zitat Si-Feng S, Jing-Fu J, Xiao-Kui G, Ya-Ping Z, De-Sheng C, Yong-Yuan G, Tao C, Xian-Long Z (2012) Biocompatibility of chitosan-coated iron oxide nanoparticles with osteoblast cells. Int J Nanomed 7:5593–5602 Si-Feng S, Jing-Fu J, Xiao-Kui G, Ya-Ping Z, De-Sheng C, Yong-Yuan G, Tao C, Xian-Long Z (2012) Biocompatibility of chitosan-coated iron oxide nanoparticles with osteoblast cells. Int J Nanomed 7:5593–5602
Zurück zum Zitat Stone V, Johnston H, Clift MJ (2007) Air pollution, ultrafine and nanoparticle toxicology: cellular and molecular interactions. IEEE Trans Nanobiosci 6:331–340CrossRef Stone V, Johnston H, Clift MJ (2007) Air pollution, ultrafine and nanoparticle toxicology: cellular and molecular interactions. IEEE Trans Nanobiosci 6:331–340CrossRef
Zurück zum Zitat Su X, Zhan X, Tang F, Yao J, Wu J (2010) Magnetic nanoparticles in brain disease diagnosis and targeting drug delivery. Curr Nanosci 1:37–46 Su X, Zhan X, Tang F, Yao J, Wu J (2010) Magnetic nanoparticles in brain disease diagnosis and targeting drug delivery. Curr Nanosci 1:37–46
Zurück zum Zitat Teeguarden JG, Hinderliter PM, Orr G, Thrall BD, Pounds JG (2007) Particokinetics in vitro: dosimetry considerations for in vitro nanoparticle toxicity assessments. Toxicol Sci 95:300–312CrossRef Teeguarden JG, Hinderliter PM, Orr G, Thrall BD, Pounds JG (2007) Particokinetics in vitro: dosimetry considerations for in vitro nanoparticle toxicity assessments. Toxicol Sci 95:300–312CrossRef
Zurück zum Zitat Vazquez-Vazquez C, Lopez-Quintela M, Bujan-Nunez M, Rivas J (2011) Finite size and surface effects on the magnetic properties of cobalt ferrite nanoparticles. J Nanopart Res 13:1663–1676CrossRef Vazquez-Vazquez C, Lopez-Quintela M, Bujan-Nunez M, Rivas J (2011) Finite size and surface effects on the magnetic properties of cobalt ferrite nanoparticles. J Nanopart Res 13:1663–1676CrossRef
Zurück zum Zitat Wahajuddin AS, Arora S (2012) Superparamagnetic iron oxide nanoparticles: magnetic nanoplatforms as drug carriers. Int J of Nanomed 7:3445–3471CrossRef Wahajuddin AS, Arora S (2012) Superparamagnetic iron oxide nanoparticles: magnetic nanoplatforms as drug carriers. Int J of Nanomed 7:3445–3471CrossRef
Zurück zum Zitat Wu W, Chen B, Cheng J, Wang J, Xu W, Lui L, Xia G, Wei H, Wang X, Yang M, Yang L, Zhang Y, Xu C, Li J (2010) Biocompatibility of Fe3O4/DNR magnetic nanoparticles in the treatment of hematologic Malignancies. Int J Nanomed 5:1079–1085 Wu W, Chen B, Cheng J, Wang J, Xu W, Lui L, Xia G, Wei H, Wang X, Yang M, Yang L, Zhang Y, Xu C, Li J (2010) Biocompatibility of Fe3O4/DNR magnetic nanoparticles in the treatment of hematologic Malignancies. Int J Nanomed 5:1079–1085
Zurück zum Zitat Zolnik B, Gonzalez-Fernandez A, Sadrieh N, Dobrovolskaia M (2010) Nanoparticles and the immune system. Endocrinology 15:458–465CrossRef Zolnik B, Gonzalez-Fernandez A, Sadrieh N, Dobrovolskaia M (2010) Nanoparticles and the immune system. Endocrinology 15:458–465CrossRef
Metadaten
Titel
Structural, stability, magnetic, and toxicity studies of nanocrystalline iron oxide and cobalt ferrites for biomedical applications
verfasst von
B. Peeples
V. Goornavar
C. Peeples
D. Spence
V. Parker
C. Bell
D. Biswal
G. T. Ramesh
A. K. Pradhan
Publikationsdatum
01.02.2014
Verlag
Springer Netherlands
Erschienen in
Journal of Nanoparticle Research / Ausgabe 2/2014
Print ISSN: 1388-0764
Elektronische ISSN: 1572-896X
DOI
https://doi.org/10.1007/s11051-014-2290-9

Weitere Artikel der Ausgabe 2/2014

Journal of Nanoparticle Research 2/2014 Zur Ausgabe

    Marktübersichten

    Die im Laufe eines Jahres in der „adhäsion“ veröffentlichten Marktübersichten helfen Anwendern verschiedenster Branchen, sich einen gezielten Überblick über Lieferantenangebote zu verschaffen.