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Erschienen in:
Engineering in Translational Medicine: An Introduction Kapitel lesen Erstes Kapitel lesen

2014 | OriginalPaper | Buchkapitel

6. Structure, Function, and Development of Blood Vessels: Lessons for Tissue Engineering

verfasst von : Hamisha Ardalani, Amir H. Assadi, William L. Murphy

Erschienen in: Engineering in Translational Medicine

Verlag: Springer London

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Abstract

The establishment of blood vessel networks is a matter of life and death for tissues and organisms. Failure to form a functional vascular network causes early death of embryos, and also dysfunction of endothelial cells (ECs) contributes to many diseases, including stroke, thrombosis, and atherosclerosis. Furthermore, there is a considerable clinical need for alternatives to the autologous vein and artery tissues used for vascular reconstructive surgeries such as lower limb bypass, arteriovenous shunts, and repairs of congenital defects to the pulmonary outflow tract. So far, synthetic materials, particularly in small-diameter applications, have not matched the efficacy of native tissues.

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Vorheriges Kapitel Tissue Engineering Applications for Peripheral Nerve Repair
Nächstes Kapitel Engineering Gene-Activated Matrices for the Repair of Articular Cartilage Defect
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Metadaten
Titel
Structure, Function, and Development of Blood Vessels: Lessons for Tissue Engineering
verfasst von
Hamisha Ardalani
Amir H. Assadi
William L. Murphy
Copyright-Jahr
2014
Verlag
Springer London
Buch
Engineering in Translational Medicine

Print ISBN: 978-1-4471-4371-0

Electronic ISBN: 978-1-4471-4372-7

Copyright-Jahr: 2014

DOI
https://doi.org/10.1007/978-1-4471-4372-7_6

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