Susceptibility Pattern of Vibrio cholerae isolated from surface water sources in Makurdi Local Government to commonly used antibiotics

Cholera is a deadly disease that has affected people globally with high rate of occurrence in Nigeria annually. The study examined the susceptibility of the infectious agent; Vibrio cholerae isolated from surface water sources in Makurdi Local Government to commonly used antibiotics. Sixteen (16) surface waters samples obtained from streams, ponds, and river were subjected to bacteriological analyses for identification of Vibrio cholerae and confirmed by biochemical analyses and Gram stain reactions. The result of the antibiotics susceptibility test showed that Vibrio cholerae was resistant to Nalidixic acid (0) followed by Augmentin (0–20 mm), Streptomycin (5–20 mm), Ceporex (0–18 mm), and Amplicin (0–20 mm). However, they were susceptible to Tarivid (12–28 mm), Reflacine (16–26 mm), Ciproflox (10–30 mm), Gentamycin (12–23 mm), and Septrin (8–20 mm). The result shows that pathogenic, toxigenic, and antibiotic resistant Vibrio cholerae are present and persist in aquatic environments. This is of serious public health implication and poses great challenges to Vibrio cholera control programs and health of the surface water consumers.