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01.04.2017 | Review

Synthesis and bio-applications of targeted magnetic-fluorescent composite nanoparticles

verfasst von: Hui Xia, Ruijie Tong, Yanling Song, Fang Xiong, Jiman Li, Shichao Wang, Huihui Fu, Jirui Wen, Dongze Li, Ye Zeng, Zhiwei Zhao, Jiang Wu

Erschienen in: Journal of Nanoparticle Research | Ausgabe 4/2017

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Abstract

Magnetic-fluorescent nanoparticles have a tremendous potential in biology. As the benefits of these materials gained recognition, increasing attention has been given to the conjugation of magnetic-fluorescent nanoparticles with targeting ligands. The magnetic and fluorescent properties of nanoparticles offer several functionalities, including imaging, separation, and visualization, while the presence of a targeting ligand allows for selective cell and tissue targeting. In this review, methods for the synthesis of targeted magnetic-fluorescent nanoparticles are explored, and recent applications of these nanocomposites to the detection and separation of biomolecules, fluorescent and magnetic resonance imaging, and cancer diagnosis and treatment will be summarized. As these materials are further optimized, targeted magnetic-fluorescent nanoparticles hold great promise for the diagnosis and treatment of some diseases.

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Titel: Synthesis and bio-applications of targeted magnetic-fluorescent composite nanoparticles
verfasst von: Hui Xia
Ruijie Tong
Yanling Song
Fang Xiong
Jiman Li
Shichao Wang
Huihui Fu
Jirui Wen
Dongze Li
Ye Zeng
Zhiwei Zhao
Jiang Wu
Publikationsdatum: 01.04.2017
Verlag: Springer Netherlands
Erschienen in: Journal of Nanoparticle Research / Ausgabe 4/2017
Print ISSN: 1388-0764
Elektronische ISSN: 1572-896X
DOI: https://doi.org/10.1007/s11051-017-3833-7

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