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Erschienen in:

01.04.2012

The impact of menopause on health-related quality of life: results from the STRIDE longitudinal study

verfasst von: Rachel Hess, Rebecca C. Thurston, Ron D. Hays, Chung-Chou H. Chang, Stacey N. Dillon, Roberta B. Ness, Cindy L. Bryce, Wishwa N. Kapoor, Karen A. Matthews

Erschienen in: Quality of Life Research | Ausgabe 3/2012

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Abstract

Purpose

We examine the impact of menopausal status, beyond menopausal symptoms, on health-related quality of life (HRQoL).

Methods

Seven hundred thirty-two women aged 40–65, regardless of health condition or menopausal status, were enrolled from single general internal medicine practice. Women completed annual questionnaires including HRQoL, and menopausal status and symptoms.

Results

The physical health composite of the RAND-36 is lower in late peri (45.6, P < .05), early post (45.4, P < .05), and late postmenopausal women (44.6, P < .01), and those who report a hysterectomy (44.2, P < .01) compared to premenopausal women (47.1), with effect sizes of Cohen’s d = .12-.23. The mental health composite of the RAND-36 is lower in late peri (44.7, P < .01), early post (44.9, P < .01), and late postmenopausal women (45.0, P < .05) and those who report a hysterectomy (44.2, P < .01) compared to premenopausal women (46.8), with effect sizes of Cohen’s d = .15–.20. Findings are comparable adjusted for menopausal symptom frequency and bother.

Conclusions

Over a 5-year follow-up period, we found a negative impact of menopause on some domains of HRQoL, regardless of menopausal symptoms. Clinicians should be aware of this relationship and work to improve HRQoL, rather than expect it to improve spontaneously when menopausal symptoms resolve.

Vorheriger Artikel Factors associated with quality of life in older adults in the United States

Nächster Artikel Asthma-like symptoms in the first year of life and health-related quality of life at age 12 months: the Generation R study

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Titel: The impact of menopause on health-related quality of life: results from the STRIDE longitudinal study
verfasst von: Rachel Hess
Rebecca C. Thurston
Ron D. Hays
Chung-Chou H. Chang
Stacey N. Dillon
Roberta B. Ness
Cindy L. Bryce
Wishwa N. Kapoor
Karen A. Matthews
Publikationsdatum: 01.04.2012
Verlag: Springer Netherlands
Erschienen in: Quality of Life Research / Ausgabe 3/2012
Print ISSN: 0962-9343
Elektronische ISSN: 1573-2649
DOI: https://doi.org/10.1007/s11136-011-9959-7

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Abstract

Purpose

Methods

Results

Conclusions

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