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Erschienen in:
2003 | OriginalPaper | Buchkapitel
Universal Biochip Readout of Directed Hamiltonian Path Problems
verfasst von : David Harlan Wood, Catherine L. Taylor Clelland, Carter Bancroft
Erschienen in: DNA Computing
Verlag: Springer Berlin Heidelberg
Enthalten in: Professional Book Archive
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A universal design for a biochip that reads out DNA encoded graphs is enhanced by a readout technique that may resolve multiple solutions of Hamiltonian path problems. A single laboratory step is used. DNA encoded graphs are labeled with many quantum dot barcodes and then hybridized to the universal biochip. Optical readouts, one for each barcode, yield multiple partial readouts that may isolate individual paths. Computer heuristics then seek additional individual paths.