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Erschienen in: Surface Engineering and Applied Electrochemistry 4/2020

01.07.2020

Validated Electrochemical Method for Simultaneous Resolution of Tyrosine, Uric Acid, and Ascorbic Acid at Polymer Modified Nano-Composite Paste Electrode

verfasst von: Chenthattil Raril, Jamballi G. Manjunatha, Doddarasinakere K. Ravishankar, Santosh Fattepur, Gurumallappa Siddaraju, Lingappa Nanjundaswamy

Erschienen in: Surface Engineering and Applied Electrochemistry | Ausgabe 4/2020

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Abstract—

In this work, an electrochemical sensor based on a poly threonine modified graphite-carbon nanotube paste electrode was developed for the investigation of tyrosine. The modification of the electrode was characterized by field emission scanning electron microscopy, cyclic voltammetry, and differential pulse voltammetry. The modified electrode shows many advantages such as simple preparation, good sensitivity, short response time, good stability and reproducibility. The developed electrode was highly selective because of the determination of tyrosine in the presence of the ascorbic acid and the uric acid. Under optimal conditions; the cyclic voltammetry provides a linear response with the concentration range from 2 × 10–6 to 2.5 × 10–5 M and 3 × 10–5 to 1.2 × 10–4 M with the limit of detection and limit of quantification values of 2.9 × 10–7 and 9.6 × 10–7 M. The developed sensor was employed for tyrosine detection in pharmaceutical sample, recoveries obtained were in a range of 99.0 to 102.80%.

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Metadaten
Titel
Validated Electrochemical Method for Simultaneous Resolution of Tyrosine, Uric Acid, and Ascorbic Acid at Polymer Modified Nano-Composite Paste Electrode
verfasst von
Chenthattil Raril
Jamballi G. Manjunatha
Doddarasinakere K. Ravishankar
Santosh Fattepur
Gurumallappa Siddaraju
Lingappa Nanjundaswamy
Publikationsdatum
01.07.2020
Verlag
Pleiades Publishing
Erschienen in
Surface Engineering and Applied Electrochemistry / Ausgabe 4/2020
Print ISSN: 1068-3755
Elektronische ISSN: 1934-8002
DOI
https://doi.org/10.3103/S1068375520040134

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